Self-sampling versus health care professional-guided swab collection for SARS-CoV-2 testingSARS-CoV-2 테스트를 위한 자가 샘플링 대 의료 전문가 안내 면봉 수집Original Paper Published on 2021-05-102022-09-10 Journal: Infection [Category] MERS, SARS, 치료기술, [키워드] anti-SARS-CoV-2 approach asked calculated Care Concordance correlated COVID-19 diagnostic reliability diagnostics disease effective evaluate evaluated Factors had more Health Health care in viral Increasing indicated Infection maintain multivariate analyses Multivariate analysis negative test Oropharyngeal oropharyngeal swab oropharyngeal swabs participant Participants PCR testing performed Personal protective equipment positive Predictive Probability questionnaire reduce reliability Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR testing SARS-CoV-2 positive individuals SARS-CoV-2 testing SARS-CoV-2-infected patient Self-sampling sensitivity supplementary material Swab symptom onset test results Viral was collected was performed [DOI] 10.1007/s15010-021-01614-9 PMC 바로가기 [Article Type] Original Paper
Comparing Nasopharyngeal Swab and Early Morning Saliva for the Identification of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 식별을 위한 비인두 면봉과 이른 아침 타액 비교Article Published on 2021-05-042022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Asymptomatic Chain Reaction collected Concordance coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 cycle threshold detection rate envelope exposure to healthcare Healthcare workers identification Isolation male participant morning nasopharyngeal Nasopharyngeal swab NP swab NPs pandemic participant polymerase chain polymerase chain reaction positive PPE processed quarantine RdRP RdRp gene real time Real time reverse transcription polymerase chain reaction recruited reduce respiratory reverse transcription RNA-dependent RNA polymerase RT-PCR Saliva saliva specimen saliva specimens sample collection SARS-CoV-2 SARS-CoV-2 surveillance significantly lower single center specimen specimen collection specimens surveillance testing Taking tested Transmissibility virus was performed [DOI] 10.1093/cid/ciaa1156 PMC 바로가기 [Article Type] Article
Usability and Acceptability of Home-based Self-testing for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibodies for Population Surveillance인구 감시를 위한 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 항체에 대한 자가 진단의 유용성 및 수용 가능성Article Published on 2021-05-042022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, [키워드] acceptability acute respiratory syndrome Adults antibody Blood can be used carried clinician Concordance coronavirus coronavirus 2 COVID-19 England feasible feedback Guidance home home-testing IMPROVE Interpretation lateral flow lateral flow immunoassay LFIA limitation MOST National Participants Population provided Public Questionnaires rapid response reported respiratory SARS-CoV-2 Usability Volunteer was obtained [DOI] 10.1093/cid/ciaa1178 PMC 바로가기 [Article Type] Article
In vitro safety “clinical trial” of the cardiac liability of drug polytherapyArticle Published on 2021-05-032022-10-04 Journal: Clinical and translational science [Category] SARS, 임상, [키워드] accelerate antioxidant arrhythmia authorization biologic Biomarker Chronic exposure clinical measurements clinical trial clinical trials clinician Concordance contractile coronavirus disease COVID‐19 decrease drug drug response Drug screening Effect elicited Emergency FDA food HCQ heart muscle help Hydroxychloroquine include increase in Infection monotherapy morphology MPS outcomes Patient Phase I platform pluripotent stem cells Potential predicted QT interval QT prolongation Repurposed drugs Safe SARS‐CoV‐2 serum tissue treat trials was measured [DOI] 10.1111/cts.13038 PMC 바로가기 [Article Type] Article
U-survival for prognostic prediction of disease progression and mortality of patients with COVID-19Article Published on 2021-04-292022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] Analysis automated bootstrap can be used Chest CT image Concordance confidence interval coronavirus disease COVID-19 COVID-19 patients COVID-19 positive patient COVID-19 progression deep learning Disease progression Disease-free survival group healthcare service hospitals introduced Kaplan–Meier survival curve Laboratory management methodology Mortality Patient patients with COVID-19 predictor prognostic Prognostic markers rapid increase significantly higher stratified survival tomography viral infection [DOI] 10.1038/s41598-021-88591-z PMC 바로가기 [Article Type] Article
Evaluation of High-Throughput SARS-CoV-2 Serological Assays in a Longitudinal Cohort of Patients with Mild COVID-19: Clinical Sensitivity, Specificity, and Association with Virus Neutralization Test경증 COVID-19 환자의 세로 코호트에서 처리량 SARS-CoV-2 혈청학적 분석 평가: 임상 민감도, 특이도 및 바이러스 중화 테스트와의 연관성Article Published on 2021-04-292022-09-11 Journal: Clinical Chemistry [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] Antibody Response Antibody titers Area association AUC best can not clinical clinical sensitivity clinical specificity collected Concordance Course COVID-19 detect DiaSorin disease evaluated except for functional greater health-care Health-care workers healthcare worker IgA IgG IgM longitudinal lowest mild patient mild patients neutralization test Neutralizing antibodies neutralizing antibody neutralizing antibody titers Neutralizing titer ranged RBD Receptor binding domain ROC Curve RT-PCR S protein SARS-CoV-2 sensitivity sera serological Serological assay serological assays Serological tests serum Siemens specificity specimen subset Test the RBD the S protein Total Virus neutralization virus neutralization test VNT with COVID-19 [DOI] 10.1093/clinchem/hvaa336 PMC 바로가기 [Article Type] Article
Evaluation of RT-qPCR and Loop-Mediated Isothermal Amplification (LAMP) Assays for the Detection of SARS-CoV-2 in ArgentinaArticle Published on 2021-04-282022-10-31 Journal: Genes [Category] COVID-19, SARS, [키워드] amplified analyzed calculate calibrated clinical samples clinical sensitivity clinical specificity Concordance Consensus contribute detection diagnosis of SARS-CoV-2 diagnostic difference evaluate evaluated greater information isothermal amplification limit of detection log molecular N gene Pan polymerase chain positive provided ranged RdRp gene reference method RT-LAMP RT-qPCR SARS-CoV-2 sensitivity specificity Standard target gene the SARS-CoV-2 Variation was used WHO World Health Organization [DOI] 10.3390/genes12050659 PMC 바로가기 [Article Type] Article
Disparities of SARS-CoV-2 Nucleoprotein-Specific IgG in Healthcare Workers in East London, UKMedicine Published on 2021-04-272022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Abbott anti-Nucleocapsid IgG antibody Antibody detection Architect Asian black category central London Concordance conducted COVID-19 COVID-19 symptom declining demonstrated determine diagnostic disparity East Effects enrolled enrolment Ethnicity evaluate evaluated Follow-up greater HCW healthcare healthcare worker Healthcare workers hospital hypertension IgG independent predictor Laboratory tests London marker MONITOR NHS Older age participant Participants persistence plasma sample point-of-care positive Prevalence Rapid test Reinfection representing retained risk factor Risk factors SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-CoV-2 IgG antibody SARS-COV-2 infection Sero-surveillance seroconverted severe COVID-19 illness spread of COVID-19 Trust worker [DOI] 10.3389/fmed.2021.642723 PMC 바로가기 [Article Type] Medicine
Serological Tests in the Detection of SARS-CoV-2 AntibodiesArticle Published on 2021-04-092022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] activities analyzed anti-SARS-CoV-2 antibodies antibodies antibody Cohort Concordance concordance rate contagious detect detection develop Early detection exhibited FIVE greater Health healthcare healthcare personnel highest Humoral immunity IgM/IgG Immunity individual Infection joint lowest management PCR performed polymerase reflected resources Retrospective study SARS-CoV-2 Sensitivity and specificity Serological assay serological test Serological testing Serological tests Spain Test tested translate Treatment vulnerable patients while [DOI] 10.3390/diagnostics11040678 PMC 바로가기 [Article Type] Article
Self-sampling of capillary blood for SARS-CoV-2 serologySARS-CoV-2 혈청학을 위한 모세혈관 자가 샘플링Article Published on 2021-04-082022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI analysed Analysis antibody Blood blood collection capillary capillary blood capillary blood samples Cohen’s kappa coefficient collected Concordance COVID-19 detect Diagnosis Dried blood spots eight Epidemiology feasible Filter Paper heparin IgG ELISA immune response immunology Infectious diseases Laboratory Large-scale testing Lateral flow tests lithium Lithium heparin nine not affect participant plasma powerful tool reference standard room temperature SARS-CoV-2 sensitivity serological assessment Serological testing serology storage temperature Transmission venepuncture venous venous blood viral infection [DOI] 10.1038/s41598-021-86008-5 PMC 바로가기 [Article Type] Article