A patient with end-stage renal disease who recovered from coronavirus disease 2019 then received a kidney transplant2019년 코로나바이러스 질병에서 회복된 후 신장 이식을 받은 말기 신장 질환 환자Case Reports Published on 2021-08-012022-09-11 Journal: Transplant immunology [Category] Coronavirus, SARS, 치료제, [키워드] antibody Chest computed tomography Clinical course complications Computed tomography coronavirus disease Coronavirus disease 2019 COVID-19 described End End stage renal disease End-stage renal disease ESRD feasible IgG IgG titer immunosuppressive indicated kidney kidney transplant Kidney transplantation Laboratory results management Patient PCR profiles recovering from COVID-19 regimen renal renal disease subsequent Symptoms the patient [DOI] 10.1016/j.trim.2021.101395 PMC 바로가기 [Article Type] Case Reports
Mortality of patients with solid and haematological cancers presenting with symptoms of COVID-19 with vs without detectable SARS-COV-2: a French nationwide prospective cohort study검출 가능한 SARS-COV-2 유무에 따른 COVID-19 증상을 보이는 고형암 및 혈액암 환자의 사망률: 프랑스 전국 전향 코호트 연구Article Published on 2021-08-012022-09-11 Journal: British Journal of Cancer [Category] SARS, 임상, 치료기술, 치료법, [키워드] 28-day mortality age anticancer Cancer cancer centre cancer patient Cancer patients cancers cause of death clinical clinical symptom Clinical symptoms COVID COVID-19 COVID-19 case COVID-19 diagnosis COVID-19 negative COVID-19 positive patient COVID-19 positive patients COVID-19 symptom COVID-19 symptoms CT-scan death detectable diabete diabetes diagnosed enrolled Follow-up French Gender Haematological cancer high risk hospital immunosuppressive inclusion criteria independent risk factor independent risk factors lymphopenia median metastatic disease Mortality occurred over Patient patients positive positive patients presenting prospective cohort prospective cohort study receiving Registered repeated reported RT-PCR SARS-CoV-2 RT-PCR SARS-CoV2 suspicion symptoms of COVID-19 Treatment Trial [DOI] 10.1038/s41416-021-01452-4 PMC 바로가기 [Article Type] Article
Regulation of Inflammatory Cytokine Storms by Mesenchymal Stem Cells간엽줄기세포에 의한 염증성 사이토카인 폭풍의 조절Review Published on 2021-07-292022-09-12 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, [키워드] Affect Anti-inflammatory anti-inflammatory properties candidate cellular and molecular clinical trial complex coronavirus disease COVID-19 Cytokine storm syndrome death described develop disease Diseases Efficacy Factor immune regulation immune system Immunity immunosuppressive Inflammation Inflammatory factor Inflammatory response Interaction mechanism mesenchymal stem cell Mesenchymal stem cells molecular MSC MSCs Pathogenesis Pathways Sepsis shown STEM stem cell Stem cell therapy storm therapeutic Treatment vital role [DOI] 10.3389/fimmu.2021.726909 PMC 바로가기 [Article Type] Review
Long-Term Evolution of SARS-CoV-2 in an Immunocompromised Patient with Non-Hodgkin Lymphoma비호지킨 림프종을 가진 면역저하 환자에서 SARS-CoV-2의 장기적 진화Research Article Published on 2021-07-282022-09-10 Journal: mSphere [Category] MERS, SARS, 변종, 진단, 치료기술, 치료제, [키워드] A222V accelerated accumulated accumulation adaptive Administered alterations Amino acid amino acid change Antigen Community Convalescent plasma therapy convergent evolution COVID-19 Deletion epidemiological evaluate Evolution Evolution of SARS-CoV-2 Genome Genome sequencing identify immune evasion Immune status Immunocompromised Immunocompromised host immunocompromised individual immunocompromised individuals Immunocompromised patient Immunocompromised patients immunosuppressive immunosuppressive therapy infected individuals Infection long-term infection mitigate MONITOR Mutation mutations Non-Hodgkin Lymphoma occurred pandemic virus pathway Patient polymorphism Protein recent reported risk SARS-CoV-2 SARS-CoV-2 evolution SARS-COV-2 infection SARS-CoV-2 infections scenario shown single-nucleotide Single-nucleotide polymorphisms SNPs spike Spike protein Support survival the SARS-CoV-2 therapy Transmission Trigger variant variants variants of concern Viral Viral genome sequencing virus virus spike protein was performed [DOI] 10.1128/mSphere.00244-21 PMC 바로가기 [Article Type] Research Article
High-dose intravenous immunoglobulins might modulate inflammation in COVID-19 patients고용량 정맥 면역 글로불린은 COVID-19 환자의 염증을 조절할 수 있습니다Research Article Published on 2021-07-282022-09-10 Journal: Life Science Alliance [Category] SARS, 바이오마커, 진단, [키워드] Activation administration analyzed C5a chemokine chemokines clinical evolution complement Complement activation Course COVID-19 COVID-19 patient COVID-19 patients cytokine Cytokines Factor Fatty acid FIVE hepatic growth factor High-dose high-dose IVIg hospitalized COVID-19 patient Hyperinflammatory hyperinflammatory status IL-10 IL-5 IL-7 immune response immune responses immunoglobulins immunomodulator immunomodulators immunomodulatory properties immunomodulatory property immunosuppressive IMPROVE individual individuals Inflammation Inflammatory Inflammatory biomarker inflammatory biomarkers intestinal Intravenous immunoglobulin IVIG Macrophage modulate modulating patients plasma sample plasma samples Protein reduced Respiratory function restored shown treated Treatment treatment initiation Tumor tumor necrosis tumor necrosis factor [DOI] 10.26508/lsa.202001009 PMC 바로가기 [Article Type] Research Article
COVID-19 severity and mortality in multiple sclerosis are not associated with immunotherapy: Insights from a nation-wide Austrian registryResearch Article Published on 2021-07-272022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] adjusted Adjusting age anticipated Cohort Course COVID-19 COVID-19 pandemic COVID-19 severity Diagnosis diagnosis of COVID-19 died Evidence female Immunosuppressant immunosuppressive Impact insight Mild Mortality multiple sclerosis Multivariable models objective Odds ratio outcome pandemic Patient patients with COVID-19 predicted Prevalence proportion provide R 2 Result risk Risk factors SARS-CoV-2 severity significantly Treatment was determined with COVID-19 [DOI] 10.1371/journal.pone.0255316 PMC 바로가기 [Article Type] Research Article
Efficacy of Different Types of Therapy for COVID-19: A Comprehensive ReviewReview Published on 2021-07-272022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] affected Analysis analyzed Antiviral antiviral drug antiviral therapy Clinical improvement Comprehensive conditions control groups Coronavirus infection COVID-19 Critical Cytokines Data analysis decrease Dexamethasone disease Efficacy immune immune therapy immunosuppressive intravenous immunoglobulin IgG Mortality mortality rate New coronavirus not differ Patient patients with COVID-19 plasma regimen review SARS-CoV-2 shown significantly Standard therapy target therapy treated Treatment Type viral life cycle [DOI] 10.3390/life11080753 PMC 바로가기 [Article Type] Review
Adversity in early life and pregnancy are immunologically distinct from total life adversity: macrophage-associated phenotypes in women exposed to interpersonal violence초기 생애 및 임신의 역경은 전체 삶의 역경과 면역학적으로 구별됩니다: 대인관계 폭력에 노출된 여성의 대식세포 관련 표현형Article Published on 2021-07-202022-09-10 Journal: Translational Psychiatry [Category] SARS, 바이오마커, 유전자 메커니즘, [키워드] Adjusting age Anti-inflammatory anti-inflammatory cytokine CD14 CD14+ monocyte CD14+ monocytes cDNA library childhood Chronic diseases Cohort CRP cytokine Cytokines demographics early childhood early life adversity endotoxin evaluate examined exposure to Gene Expression Health Human behaviour IL-10 IL-1ra IL-1ß IL-4 IL-6 Illumina HiSeq immune immune mechanism immunologically immunosuppressive Inflammatory life Monocytes phenotype Physiology plasticity Predictive markers Pregnancy Primary outcome pro-inflammatory Psychopathology retrospective RNA sequencing seeking Sensitivity and specificity Sepsis serum severe COVID-19 socioeconomic status TNF-a Tolerance trauma Treatment women [DOI] 10.1038/s41398-021-01498-1 PMC 바로가기 [Article Type] Article
Efficacy and safety of an inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac): interim results of a double-blind, randomised, placebo-controlled, phase 3 trial in Turkey비활성화된 전체 비리온 SARS-CoV-2 백신(CoronaVac)의 효능 및 안전성: 터키에서 이중 맹검, 무작위, 위약 대조, 3상 시험의 중간 결과Clinical Trial Published on 2021-07-172022-09-12 Journal: Lancet (London, England) [Category] Fulltext, SARS, 임상, 진단, [키워드] 1:1 95% CI adverse event adverse events antibody test result bleeding disorders blood product clinical trial Cohort component CoronaVac COVID-19 criteria dose double-blind Efficacy Efficacy and safety enrolled exclusion fatality fatigue follow-up period Frequency health-care humoral hydroxide Immunoglobulin immunosuppressive inactivated individual intention-to-treat intention-to-treat population intramuscularly IQR Local median Negative PCR nine Older outcome Pain participant PCR-confirmed per 1000 person-years per protocol Phase 3 phase 3 trial Placebo placebo-controlled protocol provided randomised Randomly recruited Registered reported safety analysis safety profile SARS-CoV-2 screened second dose shown Steroids symptomatic the placebo group the vaccine therapy Tolerability trials Turkey Vaccine virion virus Volunteer whole-virion SARS-CoV-2 vaccine yielding [DOI] 10.1016/S0140-6736(21)01429-X PMC 바로가기 [Article Type] Clinical Trial
Clinical Characteristics of Hospitalized COVID-19 Patients Who Received at Least One Dose of COVID-19 VaccineArticle Published on 2021-07-132022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Absolute lymphocyte count analyzed Blood Breakthrough infection C-reactive protein clinical Clinical course clinical trial close monitoring COVID-19 COVID-19 patient COVID-19 vaccine death Efficacy European fatal COVID-19 Features Fever first dose FIVE fraction Frequency healthcare higher risk highlight Hospitalization Hospitalized immune response immunosuppressive interleukin-6 lung involvement Medicines non-responders oxygen saturation Patient procalcitonin Received recipient recipients SARS-CoV-2 second dose severe COVID-19 significant difference subject symptomatic infections the vaccine union vaccinated individuals vaccination Vaccine vaccine dose [DOI] 10.3390/vaccines9070781 PMC 바로가기 [Article Type] Article