interleukin-6 – Page 18 – Communicable Diseases Research

Identification of tear-based protein and non-protein biomarkers: Its application in diagnosis of human diseases using biosensors

Review article

Published on 2021-12-012022-10-05
Journal: International journal of biological macromolecules [Category] SARS, 바이오마커,

Cirrhosis-Associated RAS-Inflammation-Coagulation Axis Anomalies: Parallels to Severe COVID-19

Article

Published on 2021-12-012022-10-30
Journal: Journal of Personalized Medicine [Category] COVID-19,

[키워드] abnormal coagulation abnormality ACE acute respiratory distress acute respiratory distress syndrome Angiotensin-converting enzyme Antigen axis C-reactive protein characterized cirrhosis coagulation parameter correlated COVID patient COVID-19 COVID-19 patients CRP D-dimer Endothelial dysfunction exhibited fibrinolysis healthy subject IL-6 Increased increased risk Inflammation interleukin-6 investigated Liver disease Mild nine parameter Patient patients patients with COVID-19 portal hypertension RAS RAS activity renin-angiotensin-system severe COVID-19 severity significantly syndrome systemic inflammation upregulation venous vWF
[DOI] 10.3390/jpm11121264 PMC 바로가기 [Article Type] Article

Hemoperfusion and blood purification strategies in patients with COVID-19: A systematic review

COVID-19 환자의 혈액 관류 및 혈액 정화 전략: 체계적인 검토

Article

Published on 2021-12-012022-09-11
Journal: Artificial organs [Category] 바이오마커, 치료제,

[키워드] Admission antagonist approach article artificial liver asymptomatic infection Blood Blood purification Case series case sery Characteristics clinical evidence clinical trials conducted control group coronavirus coronavirus disease Coronavirus disease-19 Corticosteroid Corticosteroids COVID-19 COVID-19 patient cytokine cytokine removal Cytosorb database decrease described Evidence FIVE hemoadsorption Hemoperfusion IL-6 Inflammation intensive care intensive care unit interleukin interleukin-6 Methodological quality Mortality MOST outcome oXiris Patient patients Population pro-inflammatory state Prospective Randomized receptor receptor antagonists reduced reported Severe case severe cases Support supported supportive therapies supportive therapy suppression systematic review therapy Toraymyxin Treatment Variability Ventilation
[DOI] 10.1111/aor.14078 PMC 바로가기 [Article Type] Article

Assessing the potential correlation of polymorphisms in the IL6R with relative IL6 elevation in severely ill COVID-19 patients’

중증 COVID-19 환자에서 IL6R의 다형성과 상대적 IL6 상승의 잠재적 상관 관계 평가

Clinical Trial

Published on 2021-12-012022-09-11
Journal: Cytokine [Category] 바이오마커, 변종, 임상,

[키워드] Affect affecting Analysis Assessing association baseline Baseline assessment baseline level blood sample Blood samples clinical response Clinical studies clinical study clinical variable collected Combination Control correlation COVID-19 COVID-19 patient COVID-19 patients COVID19 COVID19 patients cytokine level cytokine levels Cytokine storm defined determine elevated Elevation Genetic Genetic variant genetic variants Glucose help highest hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient hospitalized patients identify IL-6 IL-6 inhibition IL-6 level IL-6 levels IL6 IL6R interleukin-6 Interpretation mild COVID-19 patient Mortality norm not seen outcome oxygen P-value p-value < 0.01 Participants pathophysiology patient population patients Phase 3 Placebo plasma Plasma levels Pneumonia polymorphism randomized study receiving Regulatory report robust rs2228145 Sequencing analysis serum severe and mild COVID-19 patients severe COVID-19 severe patients severity shown significantly significantly increased supplemental oxygen support tested the patient tradipitant Treatment unlikely variant variants were measured while WHO whole genome Whole genome sequencing
[DOI] 10.1016/j.cyto.2021.155662 PMC 바로가기 [Article Type] Clinical Trial

Sight-threatening intraocular infection in patients with COVID-19 in India

인도의 COVID-19 환자에서 시력을 위협하는 안내 감염

Article

Published on 2021-12-012022-09-12
Journal: Indian journal of ophthalmology [Category] SARS, 진단,

[키워드] Admission age analyzed Antibiotics antiviral drug biopsy caused Comorbidities COVID-19 COVID-19 patient COVID-19-related complication Culture discharge eight endogenous endophthalmitis Epidemiology eye eyes feature fungi hospital Hospitalization Immunosuppressive agents India Infection inhibitor intensive care unit interleukin-6 Intraocular intraocular infection. laboratory-confirmed low molecular weight majority male management microbiologically Microscopy nine ocular ophthalmic outcomes Patient patients patients died patients with COVID-19 PCR positive presenting progressed south India Standard of care supplemental oxygen Symptoms systemic corticosteroid the median Tocilizumab Treatment vitreous
[DOI] 10.4103/ijo.IJO_1474_21 PMC 바로가기 [Article Type] Article

Clinical investigation of intestinal fatty acid-binding protein (I-FABP) as a biomarker of SARS-CoV-2 infection

SARS-CoV-2 감염의 바이오마커로서의 장지방산결합단백(I-FABP)의 임상적 조사

Article

Published on 2021-12-012022-09-11
Journal: International Journal of Infectious Diseases [Category] 바이오마커,

[키워드] Admission Biomarker Brazil C-reactive protein characteristic clinical Clinical characteristics collected Concentration correlation COVID-19 COVID-19 disease COVID-19 disease severity COVID-19 patient COVID-19 patients Critically ill Critically ill patient critically ill patients cytokine cytokine level cytokine levels Cytokines damage demonstrated disease severity enrolled Enterocyte enterocytes epithelial cells exacerbated exhibit fatty Fatty acid gastrointestinal tract Hospital stay hospitalisation IL-6 Illness severity infected patient infected patients Inflammation Inflammatory response interferon interleukin interleukin-6 intestinal intestinal epithelial cells intestinal epithelial cells. Laboratory laboratory findings lesion lesions less nonsurvivor nonsurvivors Patient plasma poor prognosis Prognosis Protein receiver operating characteristic receiver operating characteristic curve recorded SARS-CoV-2 SARS-COV-2 infection suggested Urine
[DOI] 10.1016/j.ijid.2021.09.051 PMC 바로가기 [Article Type] Article

Dynamic assessment of interleukin-6 during hemodialysis and mortality in coronavirus disease-19

Observational Study

Published on 2021-12-012022-10-05
Journal: Therapeutic apheresis and dialysis : official peer [Category] SARS, 임상,

Case Report: Tocilizumab for Acute Kidney Graft Dysfunction in Patient Affected by COVID-19

Medicine

Published on 2021-11-252022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

[키워드] acute kidney Acute kidney injury acute respiratory syndrome adopted affected cause characterized contributing to coronavirus coronavirus disease COVID-19 Critical cytokine Cytokine release syndrome develop dysfunction elevated Graft graft dysfunction higher risk humanized monoclonal antibody Hyperactivation IL-6 immune immune system Immunosuppression Infection Inflammatory response interleukin-6 kidney kidney transplant management morbidity and mortality pandemic Patient receptor recipient rejection rheumatoid arthritis SARS-CoV-2 SARS-COV-2 infection solid organ systemic inflammation the WHO therapy Tocilizumab tocilizumab administration transplantation
[DOI] 10.3389/fmed.2021.732792 PMC 바로가기 [Article Type] Medicine

Plasma gp96 is a Novel Predictive Biomarker for Severe COVID-19

혈장 gp96은 심한 covid-19에 대한 새로운 예측 바이오 마커입니다.

Research Article

Published on 2021-11-242022-08-31
Journal: Microbiology Spectrum [Category] MERS, SARS, 바이오마커, 진단,

[키워드] acute respiratory illness analyzed coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients COVID‐19 Critical DAMPs danger-associated molecular pattern danger-associated molecular patterns disease disease severity effective elevated evaluate Fever Heat shock heat shock protein heat shock proteins hospital Hospitalization Hsps IL-6 IMPROVE indicated Injury interleukin interleukin-6 less Mild monocyte Monocytes non-COVID-19 patient Non-COVID-19 patients novel outcome oxidative stress patients patients with COVID-19 plasma plasma concentration plasma concentrations plasma gp96 poor prognosis positively correlated predicted Predictive predictive biomarker prognostic biomarker Protein released respiratory Respiratory illness respiratory impairment respiratory symptoms severe coronavirus disease severe COVID-19 Severe patient severe patients significantly significantly higher Viral viral infection with COVID-19
[DOI] 10.1128/Spectrum.00597-21 PMC 바로가기 [Article Type] Research Article

Blood Purification in Severe and Critical COVID-19 Patients: A Case Series of 5 Patients

Public Health

Published on 2021-11-172022-10-31
Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS,

[키워드] Acute kidney injury acute respiratory syndrome age AKI ameliorated analyzed blood gas analysis Blood purification BNP boost Brain caused Characteristics clinical Complication complications Concentration Continuous coronavirus coronavirus disease COVID-19 Critical critical COVID-19 patients discharged disease early stage evaluate the effect Fluid management hemodiafiltration hemofiltration HFNC hospital ICU Identifier IL-6 Inflammatory cytokine Inflammatory cytokine storm intensive care interferon-alpha interleukin-6 Laboratory lactate dehydrogenase LDH lymphocyte male measure nasal NIV non-invasive ventilation oxygen Oxygenation oxygenation index patients patients with COVID-19 peptide progression purification SARS-CoV-2 Serum level Sery Shock significantly Standard of care supportive care survived Symptom therapy TNT transferred Treatment university Ventilation were recorded worldwide pandemic
[DOI] 10.3389/fpubh.2021.741125 PMC 바로가기 [Article Type] Public Health