Potential treatment – Page 18 – Communicable Diseases Research

COVID-19 and ocular implications: an update

Review

Published on 2020-09-042022-10-29
Journal: Journal of Ophthalmic Inflammation and Infection [Category] COVID-19,

The COVIRL002 Trial-Tocilizumab for management of severe, non-critical COVID-19 infection: A structured summary of a study protocol for a randomised controlled trial

Letter

Published on 2020-09-032022-10-29
Journal: Trials [Category] Coronavirus, SARS,

[키워드] 1:1 48 hours absence Admission all-cause mortality Arm blinded chest imaging clinical commenced Confirmed COVID-19 criteria CRP D-dimer Data analysis database death defined demonstrated determine disease dissemination dose Efficacy element eligible participant enrolled EudraCT Evidence evidence of evidenced facilitate ferritin fibrinogen hospital humanized monoclonal antibody hyper-inflammation IL-6 IL6 immunology independent Infection inflammatory state infused inhibit interleukin-6 intravenous tocilizumab intubation investigators Ireland LDH low dose management Mater moderate to severe multicentre non-invasive ventilation number objective Older open label outcome PaO participant Patient patients with COVID-19 PCR-confirmed COVID-19 performed positive PCR Potential treatment primary endpoint Primary outcome progression protocol pulmonary randomisation randomised randomised controlled trial Randomised trial receive recruited reduced Registered reported Respiratory failure Respiratory function Sample size SARS-CoV2 infection single dose Stage stage 2 Standard Standard dose status Study protocol subject subjects subsequent systemic inflammation target temperature Therapeutics Tocilizumab treatment group Trial ULN university Ventilation website
[DOI] 10.1186/s13063-020-04680-w PMC 바로가기 [Article Type] Letter

The HMOX1 Pathway as a Promising Target for the Treatment and Prevention of SARS-CoV-2 of 2019 (COVID-19)

Review

Published on 2020-09-032022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19,

Cytokine Storm in COVID-19: “When You Come Out of the Storm, You Won’t Be the Same Person Who Walked in”

Immunology

Published on 2020-09-022022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS,

Could the antipsychotic chlorpromazine be a potential treatment for SARS-CoV-2?

항정신병제인 클로르프로마진이 SARS-CoV-2의 잠재적 치료제가 될 수 있습니까?

Article

Published on 2020-09-012022-09-11
Journal: Schizophrenia research [Category] 신약개발,

[키워드] Abstract chlorpromazine clathrin Clathrin-mediated endocytosis Potential treatment Replication SARS-CoV-2 sedative Sedative medication Viral viral replication
[DOI] 10.1016/j.schres.2020.07.015 PMC 바로가기 [Article Type] Article

Research Progress of Genetic Structure, Pathogenic Mechanism, Clinical Characteristics, and Potential Treatments of Coronavirus Disease 2019

Pharmacology

Published on 2020-08-272022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

Quality Assessment of the Chinese Clinical Trial Protocols Regarding Treatments for Coronavirus Disease 2019

Pharmacology

Published on 2020-08-272022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

[키워드] 2019 novel coronavirus allocation concealment assessment autonomous baseline China Chinese clinical clinical trial clinically conducted coronavirus disease Coronavirus disease 2019 COVID-19 cross-sectional analysis description effective Effectiveness Efficacy and safety eligibility criteria evaluate exclusion criteria finding high risk indicated Intervention investigator knowledge majority Medicine Methodological quality methodology ongoing trial Open-label outcome measures patients with COVID-19 Potential treatment protocol protocols Quality random Randomized controlled trial Randomized Controlled Trial protocol RCT recruitment regions registry remained Result risk robust screened selection bia sequence Spread Standard study inclusion subject Therapies therapy translation Treatment treatments for COVID-19 Trial trial protocol
[DOI] 10.3389/fphar.2020.01330 PMC 바로가기 [Article Type] Pharmacology

Convalescent Plasma Therapy and Its Effects On COVID-19 Patient Outcomes: A Systematic Review of Current Literature

Infectious Disease

Published on 2020-08-032022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] biochemical parameter carried Case series clinical symptom conducted convalescent plasma Convalescent plasma therapy Corona virus coronavirus disease COVID 19 COVID-19 COVID-19 patient critically ill patients current Ebola Effect Efficacy evaluate Evidence global pandemic group IMPROVE improvement Infection Influenza information limitation literature MERS-CoV Middle East MOST notable observational studies outbreak outcomes Patient patient mortality patients plasma Potential treatment radiological randomization randomized control trial respiratory review Started systematic review therapy therapy for COVID-19 Topic treating COVID-19 viruses with COVID-19
[DOI] 10.7759/cureus.9535 PMC 바로가기 [Article Type] Infectious Disease

Apelin-potential therapy for COVID-19?

Short communication

Published on 2020-08-012022-10-05
Journal: Journal of molecular and cellular cardiology [Category] SARS, 신약개발,

[키워드] ACE ACE2 acute lung injury agonist ANG-II Angiotensin-converting enzyme Apelin AT1R blockade Complication COVID-19 drug drugs elevated host cell IMPROVE Lung injury Patient penetration Potential treatment receptor renin-angiotensin system the SARS-CoV-2 therapeutic strategy therapy with COVID-19
[DOI] 10.1016/j.yjmcc.2020.06.007 [Article Type] Short communication

Hydroxychloroquine effects on psoriasis: A systematic review and a cautionary note for COVID-19 treatment

Review article

Published on 2020-08-012022-10-05
Journal: Journal of the American Academy of Dermatology [Category] SARS, 치료법,