OverCOVID: an integrative web portal for SARS-CoV-2 bioinformatics resourcesOverCOVID: SARS-CoV-2 생물정보학 리소스를 위한 통합 웹 포털Article Published on 2021-03-192022-09-10 Journal: Journal of Integrative Bioinformatics [Category] SARS, 유전자 메커니즘, [키워드] accelerate addition available data bioinformatics bioinformatics resources Biology biology of SARS-CoV-2 caused Clinical data Clinical research coronavirus COVID-19 database databases facilitate Frame genomic Health help information Interaction Novel coronavirus novel coronavirus SARS-CoV-2 Other portal produced proteomic provided Research researcher resource SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 strains scientist [DOI] 10.1515/jib-2020-0046 PMC 바로가기 [Article Type] Article
Evolutionary and genomic analysis of four SARS-CoV-2 isolates circulating in March 2020 in Sri Lanka; Additional evidence on multiple introduction and further transmissionShort Paper Published on 2021-03-162022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Asia Belgium circulating circulation Cluster collected conducted coronavirus coronavirus disease COVID-19 disease transmission England Epidemics epidemiological Epidemiological study Europe Evidence Evolution France Genetic genomic Genomic analysis Germany help highest India Italy Local Measures molecular Molecular epidemiology molecular evolution North America pandemic Patient Phylogenetic analysis Phylogeny positive patient provide reported SARS-CoV-2 SARS-CoV-2 isolate SARS-CoV-2 strain sequence South Africa Sri Lanka strain Transmission virus Wuhan, China [DOI] 10.1017/S0950268821000583 PMC 바로가기 [Article Type] Short Paper
Th1 skewed immune response of whole virion inactivated SARS CoV 2 vaccine and its safety evaluationArticle Published on 2021-03-102022-10-30 Journal: iScience [Category] COVID-19, [키워드] Abstract adjuvants agonist aluminum animal model Antibody Response Antigen BSL-3 facility carried CD4 clinical trial Concentration concentrations elevated gel humans hydroxide IFN-γ immune response Immunity immunogenicity immunology inactivated Inactivated vaccine mice Microbiology NAb titer Neutralizing antibody titer platform product profiles purified response robust Safe SARS CoV SARS-CoV-2 strain SARS-CoV-2 vaccine significantly skewed Support T lymphocyte response Th1 TLR7/8 Vaccine Vero Cell virion Virology [DOI] 10.1016/j.isci.2021.102298 PMC 바로가기 [Article Type] Article
Phytochemicals against SARS-CoV as potential drug leads잠재적 약물 리드로서 SARS-CoV에 대한 파이토케미컬Article Published on 2021-03-012022-09-11 Journal: Biomedical journal [Category] SARS, 신약개발, [키워드] accelerate against SARS-CoV Analysis analyzed antiinflammatory antimalarial drug Antimalarial drugs Antiviral antiviral drug antiviral drugs assays cellular Cluster cluster analysis coronavirus CoV cysteine derivatives develop Developing drug Drug development drugs followed by health emergency Herbal herbal medicine in vitro information Lopinavir LOPINAVIR AND RITONAVIR MERS molecular docking natural natural products Pandemics pharmaceutical industry phytochemical protease reported researcher Ritonavir Safe SARS-CoV-2 SARS-CoV-2 strain Scientific community selected strain systematic review target [DOI] 10.1016/j.bj.2020.12.002 PMC 바로가기 [Article Type] Article
Introduction into the Marseille geographical area of a mild SARS-CoV-2 variant originating from sub-Saharan Africa: An investigational study사하라 사막 이남의 아프리카에서 기원한 온화한 SARS-CoV-2 변종의 마르세유 지리적 지역 소개: 조사 연구Article Published on 2021-03-012022-09-11 Journal: Travel medicine and infectious disease [Category] SARS, 변종, 치료기술, [키워드] addition characterized China clade clinical feature Combination COVID-19 COVID-19 incidence COVID-19 patient COVID-19 patients disease Epidemic Europe France French Genes Genome genome sequence Genome sequences genomes infecting involved Maghreb Marseille Marseille-1 Mild Mutation North Nsp12 NSP2 Nsp3 ORF3a ORF8 outbreak Outbreaks Patient qPCR reached remained SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 variant sequenced significantly Strains suggested transferred Travel Univariate analysis variant Viral viral variant virus [DOI] 10.1016/j.tmaid.2021.101980 PMC 바로가기 [Article Type] Article
Geographical reconstruction of the SARS-CoV-2 outbreak in Lombardy (Italy) during the early phase초기 단계 동안 롬바르디아(이탈리아)에서 SARS-CoV-2 발생의 지리적 재구성Article Published on 2021-03-012022-09-11 Journal: Journal of medical virology [Category] SARS, 유전자 메커니즘, [키워드] aligned Analysis Bergamo Brescia Characteristics circulation clade clades clinical CLOCK Cluster Complete conducted country COVID-19 case COVID-19 cases early phase Epidemic epidemiological epidemiological surveillance full length Genetic genetic variability Genome genomic sequence GISAID database highest highlight hospital Hypothesis initial involved isolate isolates Italian Italy lombardy M gene male mapped Microbiology molecular Mutation outbreak Pandemics Patient patient identification Phylogenetic Phylogenetic analysis Pneumonia positive prevalence of COVID-19 reported SARS Coronavirus SARS-CoV-2 strain Spread Surveillance the SARS-CoV-2 transmission of SARS-CoV-2 Viral genome assembly Virology virus [DOI] 10.1002/jmv.26447 PMC 바로가기 [Article Type] Article
In Silico , In Vitro and In Cellulo Models for Monitoring SARS-CoV-2 Spike/Human ACE2 Complex, Viral Entry and Cell FusionSARS-CoV-2 스파이크/인간 ACE2 복합체, 바이러스 진입 및 세포 융합 모니터링을 위한 In Silico, In Vitro 및 In Cellulo 모델Article Published on 2021-02-252022-09-10 Journal: Viruses [Category] MERS, 변종, 치료기술, 치료제, [키워드] ACE2 ACE2 receptor acute respiratory syndrome acute respiratory syndrome coronavirus angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antiviral agent Antiviral agents approach approaches assays association binding biochemical BLI Cell Cell fusion cell line cell surface cellular cellular processe cellular processes Clinical research complex Contact coronavirus coronavirus disease Coronavirus disease 2019 COVID COVID-19 detect determine etiologic agent expressing flow cytometry fusion help house in silico in vitro Infection Interaction kinetic Lentiviral vector Model modulation MONITOR monitoring pandemic parameter pseudotyped Replication Research respiratory responsible SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spike protein Spike Protein S Spike/ACE2 complex the cell the SARS-CoV-2 therapeutic target transduction assay variant Viral viral entry viral spike protein viral spike protein S virus virus entry [DOI] 10.3390/v13030365 PMC 바로가기 [Article Type] Article
Isolation of SARS-CoV-2 strains carrying a nucleotide mutation, leading to a stop codon in the ORF 6 proteinORF 6 단백질에서 정지 코돈으로 이어지는 뉴클레오티드 돌연변이를 지닌 SARS-CoV-2 균주의 분리Case Reports Published on 2021-02-182022-09-10 Journal: Emerging Microbes & Infections [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Amino acid amino acids antibodies Antiviral antiviral activity C terminus Complete coronavirus Course COVID-19 COVID-19 pathogenesis COVID-19 patients Deletion detrimental dual GenBank database genome sequence GISAID homology homology analysis hospital host response IFN in vitro interferon isolate Italian Lineage Mutation Neutralizing activity not affect nucleotide ORF ORF6 other coronaviruses physician Protein respiratory responsible SARS-CoV-2 SARS-CoV-2 infected patients SARS-CoV-2 strain sequence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 stop codon Swab the disease the patient the SARS-CoV-2 unique Viral viral pathogenesis viral replication [DOI] 10.1080/22221751.2021.1884003 PMC 바로가기 [Article Type] Case Reports
A comprehensive profile of genomic variations in the SARS-CoV-2 isolates from the state of Telangana, India인도 텔랑가나 주에서 분리된 SARS-CoV-2의 게놈 변이에 대한 포괄적인 프로필Research Article Published on 2021-02-152022-09-10 Journal: The Journal of General Virology [Category] MERS, SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition an area clade clades collected coronavirus COVID-19 Critical death defined dominant draft expected function genomic genomic variant genomic variants genomic variation globe Host host immune system immune India infecting Interaction isolate knowledge mode Mutation mutations pandemic Phylodynamic analysis Research respiratory SARS-CoV-2 SARS-CoV-2 strain subclades subgroup the SARS-CoV-2 Transmission unique variant Viral Viral protein virus [DOI] 10.1099/jgv.0.001562 PMC 바로가기 [Article Type] Research Article
VOC 202012/01 Variant Is Effectively Neutralized by Antibodies Produced by Patients Infected before Its Diffusion in ItalyVOC 202012/01 변종 이탈리아에서 확산되기 전에 감염된 환자가 생산한 항체에 의해 효과적으로 중화Communication Published on 2021-02-112022-09-01 Journal: Viruses [Category] MERS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody appearance Apulia B.1.1.7 caused circulating coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Donor English evaluate expected health emergency Intervention Italy Lineage lineage B.1 Lineage B.1.1.7 Mutation mutations Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing titer occur pandemic Patient produced Region respiratory SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 VOC 202012/01 variant sera severe acute respiratory syndrome Coronavirus strain subject tested These data United Kingdom variant variants virus viruses VOC 202012/01 [DOI] 10.3390/v13020276 PMC 바로가기 [Article Type] Communication