Cross-protective immunity following coronavirus vaccination and coronavirus infectionResearch Article Published on 2021-12-152023-07-01 Journal: The Journal of Clinical Investigation [Category] SARS, [키워드] Adaptive immunity Cellular immune response COVID-19 Vaccines [DOI] 10.1172/JCI151969 PMC 바로가기 [Article Type] Research Article
Protein-Based Nanoparticle Vaccines for SARS-CoV-2Review Published on 2021-12-142022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Antigen presentation antigenic caused Cellular immune response clinical trial Coronavirus-2 displaying domain domains elicit Emergency use Final Healthcare system humoral immune stimulation investigated nanomedicine nanoparticle nanovaccine pandemic pathogenesis of SARS-CoV-2 protein nanoparticles protein-based nanotechnology Rapid RBD SARS-CoV-2 Spike protein Vaccine Vaccines [DOI] 10.3390/ijms222413445 PMC 바로가기 [Article Type] Review
Immunogenicity after Second ChAdOx1 nCoV-19 (AZD1222) Vaccination According to the Individual Reactogenicity, Health Status and LifestyleArticle Published on 2021-12-132022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acquisition adverse effect age antibody assays AZD1222 blood sample BMI body mass cellular Cellular immune response cellular immunity ChAdOx1 nCoV-19 chill collected correlated correlation creatinine ELISA female had no Health Health status humoral Humoral immunity identify IgG Immunity immunogenicity individual intensity investigated muscle mass neutralizing antibody Questionnaires Rash reactogenicity reflect response SARS-CoV-2 SARS-CoV-2 neutralizing antibody second second dose Sex Side effects status vaccination Vaccine Vaccines virus neutralization test were used [DOI] 10.3390/vaccines9121473 PMC 바로가기 [Article Type] Article
A Highly Conserved Peptide Vaccine Candidate Activates Both Humoral and Cellular Immunity Against SARS-CoV-2 Variant Strains고도로 보존된 펩타이드 백신 후보는 SARS-CoV-2 변종 균주에 대한 체액 및 세포 면역 모두를 활성화합니다Immunology Published on 2021-12-072022-09-11 Journal: Frontiers in Immunology [Category] SARS, 변종, 진단, [키워드] activated activating acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Against amino acids antibody antigenic peptide B cell B cells B-cell epitopes B.1.617.2 BALB/c mice binding candidate CD8 Cellular immune response cellular immunity circulating conserved convalescent serum coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cross-protection dominant Efficacy Epitopes functional generate humoral humoral immune response immunization immunized Immunological memory induce key amino acid key amino acids L452R mechanism mice mutants Neutralizing peptide Point mutation Protective provide RBD-specific antibody RBD9.1 Receptor-binding domain respiratory SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sequence sera severe acute respiratory syndrome Coronavirus specific antibodies strain Strains sustained T cell T cells T-cell T-cell Response the receptor-binding domain unique Vaccine vaccine candidate vaccine candidates [DOI] 10.3389/fimmu.2021.789905 PMC 바로가기 [Article Type] Immunology
Perspective of HLA-G Induced Immunosuppression in SARS-CoV-2 InfectionImmunology Published on 2021-12-062022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, SARS, [키워드] acute respiratory syndrome antibody production antiviral immune response Apoptosis B cell caused CD8 Cell Cellular immune response coronavirus COVID-19 COVID-19 disease dendritic cell disease disease severity expression HLA-G Host Human identify immune attack Immune cell immune inhibitory Immune receptor immune responses Immune suppression immunopathological induce induced inhibit inhibitory receptor Interaction KIR knowledge leukocyte Ligand macrophages maturation natural killer NK cell outcomes patients with COVID-19 progression provoke public health receptors regulatory cell SARS-CoV-2 SARS-COV-2 infection T cell the disease transcript upregulated viral clearance viral infections [DOI] 10.3389/fimmu.2021.788769 PMC 바로가기 [Article Type] Immunology
The Humoral Immune Response to BNT162b2 Vaccine Is Associated With Circulating CD19+ B Lymphocytes and the Naïve CD45RA to Memory CD45RO CD4+ T Helper Cells Ratio in Hemodialysis Patients and Kidney Transplant RecipientsImmunology Published on 2021-12-032022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, SARS, [키워드] alteration analyzed anti-SARS-CoV2 antibodies antibody production Antibody Response Antibody titer association B cell B cells B lymphocyte baseline BNT162b2 CD19+ CD19+ B lymphocytes CD4+ CD45RA CD45RO Cellular immune response circulating correlation dose first dose flow cytometry fraction helper Hemodialysis humoral Immunosuppressed in both group in both groups kidney transplant recipient kidney transplant recipients lymphocyte material memory memory CD4+CD45RO+ T helper cells naïve CD4+CD45RA+ T helper cells naïve Patient positive correlation provide Ratio recipient response Result SARS-CoV-2 vaccination SARS-CoV2 second dose seronegative seropositive subpopulation T cell T helper cell Transplant vaccination vaccination efficacy vaccine dose vaccine-induced antibody response [DOI] 10.3389/fimmu.2021.760249 PMC 바로가기 [Article Type] Immunology
Immune Response after SARS-CoV-2 Vaccination in Kidney Transplant Patients신장 이식 환자에서 SARS-CoV-2 백신 접종 후 면역 반응Article Published on 2021-12-032022-09-12 Journal: Medicina [Category] SARS, 진단, [키워드] Adequacy anti-SARS-CoV-2 antibody Antibody Response antibody response against Antibody titer Antibody titers Better binding antibody unit binding antibody units BNT162b2 CD19 CD19+ CD4/CD8 CD8+ cell CD8+ cells Cell Cellular immune response coefficient conducted correlated COVID-19 COVID-19 vaccination COVID-19 vaccine develop dose evaluate Factor Follow-up hemoglobin humoral Humoral and cellular immune responses immune responses Immunosuppression increase Kidney function kidney transplant Kidney transplantation leucocyte Logistic regression analysis material medication multivariate Multivariate binary logistic regression analysis mycophenolate mycophenolate mofetil objective of BNT162b2 Patient patients Pfizer-BioNTech positive correlation Predictive Prospective Study responders response Result SARS-CoV-2 seropositive significant negative correlation Spearman Spearman’s correlation Transplant vaccination Vaccine [DOI] 10.3390/medicina57121327 PMC 바로가기 [Article Type] Article
Humoral and cellular immune response and safety of two-dose SARS-CoV-2 mRNA-1273 vaccine in solid organ transplant recipients고형장기 이식 수혜자에 대한 2회 접종 SARS-CoV-2 mRNA-1273 백신의 체액 및 세포 면역 반응 및 안전성Article Published on 2021-12-012022-09-12 Journal: American journal of transplantation : official jou [Category] MERS, SARS, 진단, [키워드] anti-RBD antibody Antibody testing approved board CD4+ CD4+ T cell CD8+ T cell Cell Cellular immune response clinical research/practice Combination COVID-19 develop dose doses enrolled Ethics flow-cytometry high risk highlighting immunized Infection infection and infectious agents - viral infectious agent Infectious disease IRB mRNA-1273 COVID-19 vaccine mRNA-1273 vaccine network neutralization assays neutralizing antibody Organ transplant Patient patient population positive provided recipient response responses Safe SARS-CoV-2 serum severe disease Solid solid organ transplant sub-cohort subset T cell assays T cell response university vaccination Vaccine were assessed [DOI] 10.1111/ajt.16766 PMC 바로가기 [Article Type] Article
Immunogenicity, safety and reactogenicity of a heterogeneous booster following the CoronaVac inactivated SARS-CoV-2 vaccine in patients with SLE: a case seriesSLE 환자에서 CoronaVac 비활성화 SARS-CoV-2 백신에 따른 이종 부스터의 면역원성, 안전성 및 반응성: 사례 시리즈Article Published on 2021-12-012022-09-12 Journal: RMD Open [Category] SARS, 진단, [키워드] Autoimmune booster booster dose case sery Cellular immune response CoronaVac country COVID-19 COVID-19 pandemic disease elicited Emergency use heterogeneous heterogenous humoral immune response immunogenicity Immunosuppressed immunosuppressive immunosuppressive medications IMPROVE inactivated Inactivated vaccine inactive initial lupus erythematosus mRNA Patient reactogenicity SARS-CoV-2 vaccination SARS-CoV-2 vaccine SLE Support systemic systemic lupus erythematosus therapy vaccination Vaccine Viral vector Viral vector vaccine [DOI] 10.1136/rmdopen-2021-002019 PMC 바로가기 [Article Type] Article
Evaluation of the QuantiFERON SARS-CoV-2 interferon-ɣ release assay in mRNA-1273 vaccinated health care workersmRNA-1273 백신을 접종한 의료 종사자의 QuantiFERON SARS-CoV-2 인터페론-ɣ 방출 분석 평가Article Published on 2021-12-012022-09-11 Journal: Journal of virological methods [Category] SARS, 변종, 진단, [키워드] cellular Cellular and humoral immunity Cellular immune response cellular immune responses cellular immunity clinical medicine Cohort concern COVID-19 current diagnostic evaluate evaluated focus Health care Health care worker health care workers hepatitis B humoral Humoral immunity Humoral response immune responses indicate INF-ɣ Laboratory mRNA mRNA-1273 mRNA-1273 vaccine novel peptide peptide pool Qiagen QuantiFERON responders SARS-CoV-2 SARS-CoV-2 vaccines serology vaccination Vaccinations VOCs [DOI] 10.1016/j.jviromet.2021.114295 PMC 바로가기 [Article Type] Article