Controlled trial – Page 19 – Communicable Diseases Research

[Low dose radiotherapy for COVID-19 pneumopathy: Biological rationale and literature review]

[COVID-19 폐렴에 대한 저선량 방사선 치료: 생물학적 근거 및 문헌 고찰]

Review

Published on 2021-07-012022-09-11
Journal: Cancer radiothérapie : journal de la Société franç [Category] 임상,

Cytokine adsorption in patients with severe COVID-19 pneumonia requiring extracorporeal membrane oxygenation (CYCOV): a single centre, open-label, randomised, controlled trial

Randomized Controlled Trial

Published on 2021-07-012022-10-04
Journal: The Lancet. Respiratory Medicine [Category] 임상,

Progesterone in Addition to Standard of Care vs Standard of Care Alone in the Treatment of Men Hospitalized With Moderate to Severe COVID-19: A Randomized, Controlled Pilot Trial

Article

Published on 2021-07-012022-10-05
Journal: Chest [Category] SARS, 임상, 치료법,

[키워드] 95% CI addition administration approach assigned baseline Clinical outcome clinical status Clinical status score conducted control group control subject control subjects Controlled Controlled trial COVID-19 disease dose effective enrolled Hospital stay Hospitalized hypoxemic IMPROVE improve clinical outcome Length median men moderate Open-label outcomes Patient Primary outcome progesterone Randomized Randomly receive receiving required Safe Secondary outcomes Serious Adverse Event seven-point ordinal scale severe COVID-19 severity of illness Sex Sex difference sex difference in COVID-19 outcomes sex difference in COVID-19 outcomes. Standard Standard of care subcutaneous injection subcutaneously supplemental oxygen therapeutic intervention treated Treatment Two patient women
[DOI] 10.1016/j.chest.2021.02.024 PMC 바로가기 [Article Type] Article

A randomized double-blind controlled trial of convalescent plasma in adults with severe COVID-19

중증 COVID-19가 있는 성인의 회복기 혈장에 대한 무작위 이중 맹검 대조 시험

Clinical Trial

Published on 2021-07-012022-09-11
Journal: The Journal of Clinical Investigation [Category] SARS, 변종, 임상, 진단, 치료기술,

[키워드] 28-day mortality 95% CI 95% confidence interval adults hospitalized analyzed anti-SARS-CoV-2 baseline Brazil clinical scale clinical status conducted Controlled trial controlled trials convalescent plasma coronavirus disease Coronavirus disease 2019 COVID-19 Critical double-blind Efficacy enrolled escape mutants Evidence evidence of foundation genomic sequencing Hospitalized hypoxia infused intention-to-treat intention-to-treat population IQR median titer mutant Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples neutralization neutralizing antibody New York City no evidence of Ordinal Scale participant plasma Primary outcome randomization Randomized Randomized controlled trial Randomized controlled trials receive remained Rio de Janeiro severe coronavirus disease severe COVID-19 significantly significantly lower subset Support survival survivor treat USA
[DOI] 10.1172/JCI150646 PMC 바로가기 [Article Type] Clinical Trial

Sleep Apnea and Fetal Growth Restriction (SAFER) study: protocol for a pragmatic randomised clinical trial of positive airway pressure as an antenatal therapy for fetal growth restriction in maternal obstructive sleep apnoea

수면 무호흡증 및 태아 성장 제한(SAFER) 연구: 산모 폐쇄성 수면 무호흡증의 태아 성장 제한에 대한 산전 요법으로서 기도 양압에 대한 실용적인 무작위 임상 시험 프로토콜

Article

Published on 2021-06-292022-09-11
Journal: BMJ Open [Category] SARS, 임상,

[키워드] Admission age Anomaly Antenatal APGAR score approved Birth weight Care cause center clinical trial complications Controlled trial COVID-19 Desaturation enrolment Ethics fetal FGR gestation gestational age growth hypothesise IMPROVE include institutional review board institutional review boards intensive care intention-to-treat analysis intrauterine infection Jerusalem maternal medicine morbidity and mortality mother multicentre Neonatal neonatal intensive care unit New York Obstructive obstructive sleep apnoea OSA outcome outcomes oxygen participant perinatology positive airway pressure Pragmatic pregnancies Pregnancy pregnant women Primary outcome proceed protocol questionnaire randomised registration number restriction risk risk factor screened second trimester secondary outcome Secondary outcomes Sleep sleep apnea sleep apnoea Sleep medicine Stage stage 2 standard care Stillbirth therapy Treatment Ultrasound undergo university Washington
[DOI] 10.1136/bmjopen-2021-049120 PMC 바로가기 [Article Type] Article

Effectiveness of digital interventions to improve household and community infection prevention and control behaviours and to reduce incidence of respiratory and/or gastro-intestinal infections: a rapid systematic review

Research Article

Published on 2021-06-212022-10-28
Journal: BMC Public Health [Category] COVID-19, MERS, SARS,

[키워드] analyses analysis plan antibiotic article Behaviour Behaviour change Behavioural medicine behavioural outcomes Bia Care children China Community community health Controlled Controlled trial COVID-19 determine Digital Digital medicine disease Effectiveness eHealth evaluate Evidence gastrointestinal infections Germ handwashing Health hospital hygiene hygiene behaviour hygiene behaviours IMPROVE improvement incidence inclusion criteria Infection infection control Infection prevention information Infrastructure Intervention kindergartens lack measure Measures mechanism mode Novel coronavirus objective outcomes parent PsycINFO randomisation Randomised controlled trials reduce reduced reported required Result Risk of bias searched selective setting Seven severity supplementary material Support systematic review Transmission transmitted Trial trials was used website WeChat were excluded
[DOI] 10.1186/s12889-021-11150-8 PMC 바로가기 [Article Type] Research Article

Assessing the efficacy and safety of hydroxychloroquine as outpatient treatment of COVID-19: a randomized controlled trial

COVID-19의 외래 환자 치료로서 하이드록시클로로퀸의 효능 및 안전성 평가: 무작위 대조 시험

Randomized Controlled Trial

Published on 2021-06-182022-09-11
Journal: CMAJ open [Category] SARS, 임상, 치료제,

[키워드] 95% confidence interval Assessing assigned Chain Reaction Community Composite conducted Contact contact with Controlled trial COVID-19 COVID-19 pandemic death determine determined by did not reduce direct contact disposition effect of treatment Efficacy and safety eligible enrolment Evidence expected First wave Follow-up hazard ratio Hospitalization hospitalizations hospitalized patient hospitalized patients Hydroxychloroquine hydroxychloroquine group hydroxychloroquine treatment identification individual Invasive mechanical ventilation matching placebo mechanical ventilation Mortality outcome outcomes Outpatient outpatients participant Participants patients PCR test Placebo placebo group polymerase chain polymerase chain reaction positive RT-PCR Prevent prevented Primary outcome priority raised Randomized controlled trial Randomly reduced resulting reverse transcription reverse transcription polymerase chain reaction Ribonucleic acid RT-PCR Safety SARS-COV-2 infection secondary Secondary outcomes Serious Adverse Event Serious Adverse Events severe COVID-19 study drug survived symptom duration symptom onset the placebo group therapy Treatment Trial viral ribonucleic acid with COVID-19
[DOI] 10.9778/cmajo.20210069 PMC 바로가기 [Article Type] Randomized Controlled Trial

Toujie Quwen granule used with conventional western therapy for coronavirus disease 2019 A protocol for systematic review and meta-analysis

Coronavirus Disease 2019에 대한 기존의 서양 요법과 함께 사용되는 Toujie Quwen 과립은 체계적인 검토 및 메타 분석을위한 프로토콜

3800

Published on 2021-06-182022-08-31
Journal: Medicine [Category] meta-analysis, SARS, 치료제,

[키워드] 2019 novel coronavirus 2019-nCoV Analysis assessment CBM Chinese Clinical studies clinical study clinical trial CNKI Cochrane Library conducted Controlled trial controlled trials coronavirus disease Coronavirus disease 2019 COVID-19 database development Efficacy and safety English Epidemic Evidence exclusion criteria include Inclusion inclusion and exclusion criteria Infectious disease International Meta-analysis Novel coronavirus platform protocol Randomized controlled trial RCTs registration number researcher searched statistical analysis systematic review therapy therapy for COVID-19 Toujie Quwen granule used to evaluate VIP Web of Science
[DOI] 10.1097/MD.0000000000026370 PMC 바로가기 [Article Type] 3800

Partner-delivered HIV self-test kits with and without financial incentives in antenatal care and index patients with HIV in Malawi: a three-arm, cluster-randomised controlled trial

Articles

Published on 2021-06-152022-10-30
Journal: The Lancet. Global health [Category] COVID-19,

[키워드] 95% CI adjusted administration ANC antenatal care approach ART assigned Cluster Clusters Cohort computer-generated Contact Controlled trial diagnosed Diagnosis distribution eligible eligible patient enrolment finding funding geometric Government Health HIV HIV testing identify IMPROVE incidence rate initiative intention to treat Intervention lockdowns male nine occurred offered offset Open-label Patient patients patients with HIV Pragmatic Pregnancy Primary outcome proportion random Randomly receiving recruited Registered reported resulting risk secondary significantly more standard care standard care group Standard of care tested the mean Trial with HIV women
[DOI] 10.1016/S2214-109X(21)00175-3 PMC 바로가기 [Article Type] Articles

Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial

Randomized Controlled Trial

Published on 2021-06-122022-10-05
Journal: Lancet (London, England) [Category] SARS, 임상,

[키워드] 1:1 absence allergic reaction analysed Analysis anticoagulation assigned Bayer bleeding blinded Brazil clinical outcomes clinically Coalition Concentration Controlled trial COVID-19 COVID-19 symptom D-dimer death duration of hospitalisation Efficacy Efficacy and safety elevated Follow-up Hierarchical hospital hospitalised IMPROVE improve clinical outcome In-hospital initial intention-to-treat population intravenous medication multicentre not different occurred one patient Open-label Oral anticoagulants outcome Patient patients per day Pragmatic primary analysis Prophylactic prophylactic anticoagulation prothrombotic state randomisation randomised Randomly receive reflect Registered risk screened Seven supplemental oxygen therapeutic therapeutic anticoagulation unfractionated heparin with COVID-19 withdrawal of consent
[DOI] 10.1016/S0140-6736(21)01203-4 PMC 바로가기 [Article Type] Randomized Controlled Trial