Opportunistic mycoses in COVID-19 patients/survivors: Epidemic inside a pandemicCOVID-19 환자/생존자의 기회주의적 진균: 전염병 내부의 전염병Review Published on 2021-11-012022-09-12 Journal: Journal of infection and public health [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] Aspergillus being black Candida Clinicians Co-infection Corticosteroid Corticosteroids COVID-19 develop disease Diseases drug fatality fungal Fungal infection fungi Health Host immune Immunocompromised Immunosuppressed individual Inflammation Intrusive fungus invasive life-threatening Mucorales Opportunistic mycose pandemic pathology patients of COVID-19 physician provide researcher Secondary infection Sepsis shown survivor therapeutic therapy threat viral infection white [DOI] 10.1016/j.jiph.2021.10.010 PMC 바로가기 [Article Type] Review
Low-dose hydrocortisone in patients with COVID-19 and severe hypoxia: The COVID STEROID randomised, placebo-controlled trialRandomized Controlled Trial Published on 2021-11-012022-10-05 Journal: Acta Anaesthesiologica Scandinavica [Category] SARS, 임상, [키워드] 95% CI adjusted assigned authority benefit blinded clinical clinical trial Corticosteroid Corticosteroids COVID COVID-19 Critically ill patient days alive drug early phase Effect enrolled estimate EudraCT European Evidence hospital discharge Hydrocortisone lack low-dose matching placebo mechanical ventilation Mortality multicentre outcome pandemic parallel-group participant patients with COVID-19 Placebo placebo group placebo-controlled placebo-controlled trial Primary outcome randomisation randomised randomised clinical trial. Randomly Sample size SARS-CoV-2 serious adverse reaction severe COVID-19 severe hypoxia stratified supplementary oxygen Support the median Trial union use of corticosteroid with COVID-19 [DOI] 10.1111/aas.13941 PMC 바로가기 [Article Type] Randomized Controlled Trial
Beneficial and harmful outcomes of tocilizumab in severe COVID-19: A systematic review and meta-analysis중증 COVID-19에서 토실리주맙의 이로운 결과와 유해한 결과: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-11-012022-09-11 Journal: Pharmacotherapy [Category] 임상, 진단, [키워드] 95% CI 95% confidence interval addition Administered administration benefit clinical trials coronavirus Corticosteroid Corticosteroids COVID-19 COVID-19 patient database Evidence greater hospitalized patient hospitalized patients ICU in-hospital mortality intensive care unit intensive care units Medline database Meta-analysis Mortality observational studies observational study occurred Odds ratio outcome Patient patients hospitalized patients with COVID-19 prevented provided random-effects model randomized clinical trial RCTs receiving reported retrospective risk SARS-CoV-2 searched Secondary infection secondary infections significantly higher Standard of care symptom onset systematic review TCZ Tocilizumab treated with COVID-19 [DOI] 10.1002/phar.2627 PMC 바로가기 [Article Type] Meta-Analysis
Remdesivir: Quo vadis?렘데시비르: 쿼바디스?Review Published on 2021-11-012022-09-11 Journal: Biochemical pharmacology [Category] SARS, 치료제, [키워드] addressed adenosine administration animal model animal models Antiviral antiviral drug approved chain Chain terminator Clinical efficacy Combination Corticosteroid Corticosteroids COVID-19 Dexamethasone dosage drug duration of treatment evaluated feature GS-5734 molecular pharmacokinetics phosphoramidate ProTide RdRP remained Remdesivir ribavirin RNA-dependent RNA polymerase route Safety SARS-CoV-2 SARS-COV-2 infection Toxicity Treatment US FDA [DOI] 10.1016/j.bcp.2021.114800 PMC 바로가기 [Article Type] Review
Tocilizumab and remdesivir in hospitalized patients with severe COVID-19 pneumonia: a randomized clinical trial중증 코로나19 폐렴으로 입원한 환자를 대상으로 한 토실리주맙과 렘데시비르: 무작위 임상시험Randomized Controlled Trial Published on 2021-11-012022-09-11 Journal: Intensive care medicine [Category] 임상, 진단, 치료제, [키워드] 7-category ordinal scale 95% CI adverse event assigned benefit clinical status Combination Corticosteroid Corticosteroids COVID-19 COVID-19 pneumonia Cox proportional hazard defined demonstrated died double-blind enrolled evaluated greater hospital discharge hospitalized patient intravenously investigator median time Multicenter trial occurred Ordinal Scale other treatment other treatments oxygen Patient patients patients hospitalized Placebo placebo-controlled Pneumonia Primary outcome provide randomization Randomized randomized clinical trial Randomly receive Remdesivir Serious Adverse Events severe COVID-19 Severe COVID-19 pneumonia supplemental oxygen Tocilizumab Trial [DOI] 10.1007/s00134-021-06507-x PMC 바로가기 [Article Type] Randomized Controlled Trial
Molecular mimicry of NMDA receptors may contribute to neuropsychiatric symptoms in severe COVID-19 casesNMDA 수용체의 분자 모방은 심각한 COVID-19 사례에서 신경 정신병 증상에 기여할 수 있습니다Review Published on 2021-10-282022-09-12 Journal: Journal of Neuroinflammation [Category] MERS, SARS, 진단, [키워드] Agitation Altered mental status antibody auditory auditory hallucination autoantibody Autoimmune Autoimmune encephalitis catatonia cerebrospinal fluid characteristic condition confirmed case confirmed cases Confusion contribute Corticosteroid COVID-19 develop diagnostics dysfunction eight Encephalitis feature Hallucination High-dose Immunoglobulin Immunomodulatory agent Immunotherapy individual Infection Inflammation memory molecular mimicry neurological Neuropsychiatric NMDA NMDA receptor Occurrence Patient performed Psychiatric receptor reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections severe COVID-19 severe SARS severe SARS-CoV-2 steroid supplementary material Symptom Symptoms systematic review treated Working memory [DOI] 10.1186/s12974-021-02293-x PMC 바로가기 [Article Type] Review
A multicenter cross-sectional French study of the impact of COVID-19 on neuromuscular diseasesResearch Published on 2021-10-262022-10-29 Journal: Orphanet Journal of Rare Diseases [Category] COVID-19, MERS, SARS, [키워드] affected carried caused clinical Cohort cohort of patient collected Corticosteroid COVID-19 COVID-19 severity cross-sectional death diabetes diabetic patient First wave form French greater had no health condition higher risk hypertension Immunosuppressant moderate multicenter network neuromuscular disease neuromuscular diseases outcome pandemic Patient patients physician prevalence of COVID-19 Prognosis reported Result risk risk factor serious complication severe COVID-19 severity significantly with COVID-19 [DOI] 10.1186/s13023-021-02090-y PMC 바로가기 [Article Type] Research
Case Report: Cyclophosphamide in COVID-19 – when an absolute contraindication is an absolute necessityCase Report Published on 2021-10-252022-10-31 Journal: F1000Research [Category] COVID-19, MERS, SARS, [키워드] abnormality Acute kidney injury acute respiratory distress alveolar alveolar haemorrhage Antibiotics antibody antibody panel carried changes in Corticosteroid Course COVID-19 COVID-19 diagnosis Cyclophosphamide cytoplasmic Diagnosis Dyspnoea Fever greater had no immunoglobulins in some initial treatment initiated intravenous kidney Kidney function knowledge Laboratory Laboratory test life-threatening lung other disease p-ANCA parameter Patient Pneumonia positive prevented pulmonary radiological Remdesivir renal retrieved SARS-CoV-2 syndrome the patient treating SARS-CoV-2 infection Treatment Vasculitis [DOI] 10.12688/f1000research.55625.2 PMC 바로가기 [Article Type] Case Report
Treatment for COVID-19—a cohort study from Northern ItalyCovid-19에 대한 치료-이탈리아 북부의 코호트 연구Observational Study Published on 2021-10-252022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 임상, 진단, 치료법, 치료제, [키워드] Antiviral Azithromycin clinical evaluation cohort study Combination Corticosteroid COVID-19 patient COVID-19 therapeutics Epidemiology heparin High dose Italy low molecular weight low molecular weight heparin lower mortality multicentre multivariable retrospective cohort study Support survival Tocilizumab Treatment viral infection [DOI] 10.1038/s41598-021-00243-4 PMC 바로가기 [Article Type] Observational Study
Disseminated Cryptococcus neoformans infection associated to COVID-19Case Report Published on 2021-10-222022-10-29 Journal: Medical Mycology Case Reports [Category] COVID-19, [키워드] coronavirus 2 Corticosteroid Corticosteroids COVID-19 Cryptococcus Cryptococcus neoformans drug Fungal infection High dose immune dysregulation Immunosuppression increase Infection Novel coronavirus opportunistic Infections Organizing pneumonia Patient respiratory risk SARS-CoV-2 severe COVID-19 Treatment [DOI] 10.1016/j.mmcr.2021.10.001 PMC 바로가기 [Article Type] Case Report