endothelial – Page 19 – Communicable Diseases Research

Cell-Free Hemoglobin Does Not Attenuate the Effects of SARS-CoV-2 Spike Protein S1 Subunit in Pulmonary Endothelial Cells

Article

Published on 2021-08-222022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, SARS,

Endothelial Dysfunction, Inflammation, and Oxidative Stress in COVID-19—Mechanisms and Therapeutic Targets

COVID-19의 내피 기능 장애, 염증 및 산화 스트레스 - 메커니즘 및 치료 목표

Review

Published on 2021-08-212022-09-12
Journal: Oxidative Medicine and Cellular Longevity [Category] MERS, SARS, 진단,

[키워드] acute respiratory distress acute respiratory distress syndrome alveolar damage cardiovascular system caused characterized clinical manifestations Coagulopathy COVID-19 COVID-19 pandemic COVID-19 pathogenesis Cytokine storm death disease endothelial Endothelial dysfunction endotheliopathy form healthcare Inflammation investigated lung lung damage mechanism Mild symptom mild symptoms New observation outbreak oxidative stress respiratory distress Respiratory distress syndrome Respiratory failure responsible SARS-CoV-2 SARS-COV-2 infection syndrome target the disease therapeutic target therapeutic targets virus with COVID-19
[DOI] 10.1155/2021/8671713 PMC 바로가기 [Article Type] Review

Temporal change in Syndecan-1 as a therapeutic target and a biomarker for the severity classification of COVID-19

Research

Published on 2021-08-162022-10-29
Journal: Thrombosis Journal [Category] COVID-19,

[키워드] Admission Analysis analyzed Biomarker Care center city classification Clinical data Coronavirus disease 2019 Course COVID-19 COVID-19 patient Critical critical COVID-19 patient critical COVID-19 patients CRP level ELISA endothelial endothelial injury Factor FIVE glycocalyx high mortality intensive care laboratory data LDH no significant difference pathogenesis of COVID-19 Platelet required Result selected severe COVID-19 severe COVID-19 patient severe respiratory failure severity severity of COVID-19 significant difference significantly significantly higher SOFA score Syndecan-1 Temporal therapeutic target two groups university Yokohama
[DOI] 10.1186/s12959-021-00308-4 PMC 바로가기 [Article Type] Research

Well-Known and Novel Players in Endothelial Dysfunction: Updates on a Notch(ed) Landscape

Review

Published on 2021-08-112022-10-28
Journal: Biomedicines [Category] COVID-19,

[키워드] ACEi Activation alteration Angiotensin converting enzyme inhibitors angiotensin II receptor blockers ANGPTL3 ARB Atherosclerosis Biomarker can be used cardiovascular disease Cardiovascular disorders cellular changes circulating Clinical practice Complication continuum Coronary heart disease coronavirus disease COVID-19 Diabetic drug dysfunction Efficacy endothelial Endothelial dysfunction endothelial function Endothelium enzyme evaluate event heart failure hypertension hypertensive patients implication inhibitor Injury Intervention landscape molecular Mortality Myocardial infarction Notch novel obese predict Prevent Prognostic factor progression pyroptosis respond severity Signaling statin subject the disease therapy thrombus formation vascular disorders viral infection
[DOI] 10.3390/biomedicines9080997 PMC 바로가기 [Article Type] Review

Sustained expression of inflammatory monocytes and activated T cells in COVID‐19 patients and recovered convalescent plasma donors

Original Article

Published on 2021-08-062022-10-30
Journal: Immunity, Inflammation and Disease [Category] COVID-19, MERS, SARS,

[키워드] activated T cell activated T cells activating acute respiratory syndrome Analysis analyzed B cell B‐cell Biliary CCR2 CD8 cellular response chemotactic convalescent plasma coronavirus coronavirus disease COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 CX3CR1 cytokine cytokine production Cytokines disease Donor endothelial expected expression flow cytometry group growth healthy individual healthy subjects IL‐6 Immune cell immune cells immune response Immunity Infection infiltration Inflammatory marker inflammatory monocyte inflammatory protein inhibitory Leptin Ligand Lung injury Macrophage main mechanism Migration Mild MIP moderate monocyte Monocyte activation Monocytes New Patient patients performed Plasma cytokine positive Protein Proteins proteomics receptor recovered patient recovered patients recruited reduction in Result Saa1 serum significant increase sustained T cells target tissue Vascular
[DOI] 10.1002/iid3.476 PMC 바로가기 [Article Type] Original Article

What cellular mechanisms are related to thromboembolic events in patients with COVID-19?

Review Article

Published on 2021-08-022022-10-30
Journal: Jornal Vascular Brasileiro [Category] COVID-19,

Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2

COVID-19의 내피 기능 장애는 즉각적인 주의가 필요합니다: SARS-CoV-2로 인한 염증에서 내피의 새로운 역할

Article

Published on 2021-08-012022-09-11
Journal: Frontiers of medicine [Category] SARS, 유전자 메커니즘,

Endothelial function provides early prognostic information in patients with COVID-19: A cohort study

내피 기능은 COVID-19 환자의 조기 예후 정보를 제공합니다: 코호트 연구

Observational Study

Published on 2021-08-012022-09-11
Journal: Respiratory medicine [Category] SARS, 바이오마커, 임상, 치료기술,

[키워드] Analysis assessment assessments blood flow cardiovascular risk Characteristics clinical clinical evaluation cohort study COVID-19 COVID-19 group cutoff point death deaths deficiency detect diagnosed diagnosed with COVID-19 diffuse intravascular coagulation discharge endothelial Endothelial dysfunction endothelial function Endothelium evaluated Flow-mediated dilation (FMD) greater Hospital stay Hospitalization Hospitalized hospitalized patient information intravascular coagulation Mortality non-COVID-19 group observational study occurred Patient patients without COVID-19 performed phenotype predict Probability prognostic prospective observational study prothrombotic provide reduction in remained significantly Vascular vascular dysfunction
[DOI] 10.1016/j.rmed.2021.106469 PMC 바로가기 [Article Type] Observational Study

Elevated plasma ICAM1 levels predict 28-day mortality in cirrhotic patients with COVID-19 or bacterial sepsis

Research article

Published on 2021-08-012022-10-05
Journal: JHEP Reports [Category] 바이오마커,

[키워드] 28-day mortality 95% CI aetiology alcohol AUC Bacterial sepsis Biomarker Biomarkers cirrhosis Coagulation COVID-19 Critically ill detrimental diagnostic dysfunction elevated endothelial endothelial injury Factor growth factor hazard ratio high plasma level hospitalized patient ICAM1 ICU ICU admission increased mortality independent indicate Infection infections Injury intensive care intercellular investigated liver Liver cirrhosis Liver disease Mortality not differ Organ failure Pathogenesis Patient patients patients with COVID-19 plasma positively correlated predict predicted predictor prognostic biomarker Prognostic value receptor recorded reduced renal reported Result Sepsis severe COVID-19 significantly SOFA subgroup of patients Vascular VEGFR1 von Willebrand factor was increased
[DOI] 10.1016/j.jhepr.2021.100303 [Article Type] Research article

Circulating Von Willebrand factor and high molecular weight multimers as markers of endothelial injury predict COVID-19 in-hospital mortality

내피 손상의 표지자로서 순환하는 폰 빌레브란트 인자와 고분자량 다량체가 COVID-19 병원 내 사망률을 예측합니다

Article

Published on 2021-08-012022-09-11
Journal: Angiogenesis [Category] MERS, SARS, 바이오마커,

[키워드] Accuracy adjusted Admission age Analysis Antigen best Biomarker BMI C-reactive protein Clinical severity Cohort coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 adult patients COVID-19 outpatient COVID-19 outpatients COVID-19 patient COVID-19 patients Cox proportional hazard model Critical critical patients cut-off D-dimer levels endothelial endothelial activation Endothelial dysfunction endothelial injury Endotheliitis enrolled excess forms hazard hospitalized patient in-hospital mortality intensive care intensive care unit IQR Kaplan-Meier estimator laboratory-confirmed Laboratory-confirmed COVID-19 marker median Microthrombosis Mild molecular weight Mortality MOST Multimers Outpatient Patient patients hospitalized predict Predictive respiratory Respiratory disease ROC Curve scaled significantly higher tested transferred von Willebrand factor vWF were measured
[DOI] 10.1007/s10456-020-09762-6 PMC 바로가기 [Article Type] Article