Detecting COVID-19 infection hotspots in England using large-scale self-reported data from a mobile application: a prospective, observational study모바일 애플리케이션의 대규모 자체 보고 데이터를 사용하여 영국의 COVID-19 감염 핫스팟 감지: 전향적, 관찰 연구Observational Study Published on 2021-01-012022-09-11 Journal: The Lancet. Public Health [Category] Fulltext, MERS, 임상, 치료제, [키워드] 95% CI age assessment assessments calculated chain change chronic chronic disease community infection community transmission complementary Council country COVID COVID Symptom Study app COVID-19 COVID-19 infection dataset Department detect Disease surveillance effective Engineering England estimate foundation Government granular healthy heart help highest highlight hotspot identify incidence incidence of COVID-19 incidence rate incidence rates increases in information Intervention Local Logistic regression Markov Markov chain Medical Research Council National observational study office ONS pandemic PCR tests Poisson Prevalence provided recorded Region reported Reproduction number resource RT-PCR RT-PCR test RT-PCR tests Science sensitivity Society spread of COVID-19 Statistics survey Swab Swab test Symptom Symptoms test results the disease Wellcome Trust Zoe Global [DOI] 10.1016/S2468-2667(20)30269-3 PMC 바로가기 [Article Type] Observational Study
Measuring the Outcomes of Maternal COVID-19-related Prenatal Exposure (MOM-COPE): study protocol for a multicentric longitudinal project산모의 COVID-19 관련 산전 노출 결과 측정(MOM-COPE): 다심적 종단 프로젝트를 위한 연구 프로토콜Article Published on 2020-12-312022-09-11 Journal: BMJ Open [Category] SARS, 유전자 메커니즘, [키워드] approved association behavioural Birth Cohort collected conception contribute coping strategies COVID-19 Critical depressive developmental DNA methylation during pregnancy Effect enrolled Epidemic Epigenetic Ethics ethics committee Europe exposure exposure to Health hotspot Infant Infants infection rate Interaction International Italy Maternal mechanism Mental mental health methodological Methylation mother National outcomes Pavia peer-reviewed perinatology Pregnancy prenatal programming protocol Psychological psychological status Psychological stress registration number Regulation respiratory Respiratory disease Result retrospective retrospective data risk saliva sample saliva samples sensitivity Spread Stress Study protocol Symptoms virus [DOI] 10.1136/bmjopen-2020-044585 PMC 바로가기 [Article Type] Article
Artificial intelligence predicts the immunogenic landscape of SARS-CoV-2 leading to universal blueprints for vaccine designs인공 지능은 백신 설계를 위한 보편적 청사진으로 이어지는 SARS-CoV-2의 면역원성 환경을 예측합니다.Article Published on 2020-12-232022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 변종, 신약개발, 유전자 메커니즘, 치료기술, 치료제, [키워드] acute respiratory syndrome coronavirus allele Analysis analyzed Antigen presentation Antigen processing and presentation Applied immunology approach artificial intelligence autoimmune responses Biotechnology broad spectrum caused Cell cells chance Combination Computational biology and bioinformatics coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 Coverage COVID-19 Data integration database develop effective epitope Epitopes help HLA HLA haplotype HLA haplotypes HLA-A HLA-B HLA-DR homology host immune system hotspot human population identify immunization immunogenic immunology Immunotherapy individual input MHC class I MHC class II Mutation NEC nonsynonymous mutation Nonsynonymous mutations Novel coronavirus occurred pandemic predict predicted predictor Protein proteome reduce reduced Region respiratory robust SARS-CoV-2 SARS-CoV-2 mutations SARS-CoV-2 proteome sequence Sequence conservation severe acute respiratory syndrome coronavirus 2 statistically significant subset surface antigen T-cell epitope T-cell epitopes Vaccine Vaccine design Vaccines Viral Virtual drug screening virus [DOI] 10.1038/s41598-020-78758-5 PMC 바로가기 [Article Type] Article
Potentially adaptive SARS-CoV-2 mutations discovered with novel spatiotemporal and explainable AI modelsResearch Published on 2020-12-232022-11-01 Journal: Genome Biology [Category] COVID-19, SARS, [키워드] adaptive adaptive mutation Algorithm Analysis build change contrary coronavirus COVID-19 COVID-19 pandemic dispersal drug expression Frequency functional Haplotype Helicase High-resolution Host hotspot identify implication information Local adaptation molecular molecular evolution Mutagenesis Mutation nsp13 Pandemics Positive selection Pro rapid expansion reduced Result RNA-dependent RNA polymerase robust SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 mutation sequence spatiotemporal spike glycoprotein Spread subsequent Surveillance These data tissue Transmission USA virus [DOI] 10.1186/s13059-020-02191-0 PMC 바로가기 [Article Type] Research
Seroprevalence of Specific Antibodies against SARS-CoV-2 from Hotspot Communities in the Dominican Republic도미니카 공화국의 핫스팟 커뮤니티에서 SARS-CoV-2에 대한 특정 항체의 혈청 유병률Articles Published on 2020-12-212022-09-12 Journal: The American Journal of Tropical Medicine and Hygi [Category] MERS, SARS, 진단, [키워드] age All participants antibody circulation Community distribution effective intervention effort healthcare highlight hotspot identify IgG IgG antibodies IgG positivity IgM IgM and IgG Infection introduced Outbreaks participant participated pathogen proportion SARS-CoV-2 serological Seroprevalence Specific subsequent Surveillance survey virus [DOI] 10.4269/ajtmh.20-0907 PMC 바로가기 [Article Type] Articles
Racial Segregation, Testing Site Access, and COVID-19 Incidence Rate in Massachusetts, USAArticle Published on 2020-12-192022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] access access to testing site American Analysis applied Asians association Care correlated COVID-19 COVID-19 cases COVID-19 incidence COVID-19 incidence rate COVID-19 infection COVID-19 infections COVID-19 outbreak COVID-19 transmission Effectiveness estimate evaluate groups Health Hispanic hotspot incidence rate Infection less Massachusett Massachusetts populations positive poverty Previous studies Racial racial segregation Rate reducing Region Regression model segregation significantly Site social distancing Spatial regression statistically susceptibility Testing USA variable variables with COVID-19 [DOI] 10.3390/ijerph17249528 PMC 바로가기 [Article Type] Article
Culture-free genome-wide locus sequence typing (GLST) provides new perspectives on Trypanosoma cruzi dispersal and infection complexity무배양 게놈 전체 유전자좌 서열 유형 지정(GLST)은 트리파노소마 크루지 분산 및 감염 복잡성에 대한 새로운 관점을 제공합니다.Research Article Published on 2020-12-162022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] agarose gel alternate allele frequency amplification amplify analyzed approach biases capture capture method Cell Chagas disease Chain Reaction city clone Co-infection collected Complete complex correlation correlations Culture detect dispersal distribution DNA Ecuador epidemiological epidemiological surveillance evaluate Ex vivo flexible frequency distributions generate Genetic Genetic polymorphism Genetic variation Genome genomes genotyping hotspot identify infecting Infection infection source Infectious disease Infectious diseases information intestinal involved library limitation lineages locus marker metagenomic minimum parasite parasites pathogen Pathogenic microorganisms Perspective polymerase chain polymerase chain reaction polymerase chain reactions polymorphism powerful tool primer principle provide purification representing Research Result sequence Sequencing single-nucleotide Single-nucleotide polymorphisms SNP Spectrum Strains subsequent subset Surveillance target target pathogen Trypanosoma Trypanosoma cruzi vector Venezuela [DOI] 10.1371/journal.pgen.1009170 PMC 바로가기 [Article Type] Research Article
Characterizing COVID-19 and Influenza Illnesses in the Real World via Person-Generated Health DataArticle Published on 2020-12-132022-10-04 Journal: Patterns [Category] 치료기술, [키워드] and tested for one domain/problem implemented activity tracker Arm cohorts Continuous data COVID-19 COVID-19 diagnosis COVID-19 patient develop diagnosed Digital health DSML 2: Proof-of-Concept: Data science output has been formulated examined Fitbit flu Frame Health highlight hotspot ILI illness illness onset include individual influenza-like illness magnitude measure median overlap overlapping Patient peaked person-generated health data physiological presenting Prevalence reported respiratory illnesses SARS-CoV-2 significant changes in significantly more Symptom symptom presentation symptoms onset viral infection while [DOI] 10.1016/j.patter.2020.100188 PMC 바로가기 [Article Type] Article
Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2오스트리아에서 발생한 슈퍼전파 사건의 게놈 역학은 SARS-CoV-2의 돌연변이 역학 및 전파 특성을 보여줍니다Research Article Published on 2020-12-092022-09-10 Journal: Science Translational Medicine [Category] MERS, SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 allele Analysis average Cluster Contact tracing Containment coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 COVID-19 pandemic defined determine disease disease control epidemiological epidemiological surveillance epidemiologically Epidemiology estimation Europe event Evidence evidence of examined First wave fixation genomic High-resolution hotspot individuals with COVID-19 Infection initial International Mutation observation pandemic performed phylogenetic analyses Phylogenetic analysis phylogenetic cluster power profile progressed provide provided reconstruction respiratory reveal SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 mutations SARS-CoV-2 particles SARS-CoV-2 transmission Sequencing severe acute respiratory syndrome Coronavirus Spread spring superspreading event superspreading events Surveillance the SARS-CoV-2 Transmission Viral Viral genome sequencing viral mutation viral spread virus virus samples virus transmission whole-genome sequencing [DOI] 10.1126/scitranslmed.abe2555 PMC 바로가기 [Article Type] Research Article
Spatiotemporal Assessment of COVID-19 Spread over Oman Using GIS TechniquesOriginal Article Published on 2020-12-082022-10-31 Journal: Earth Systems and Environment [Category] COVID-19, [키워드] \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \us acute respiratory syndrome adopted Analysis assessment autocorrelation caused Clustering confidence level coronavirus COVID-19 COVID-19 case COVID-19 infection dataset directional disease Epidemic FIVE GIS help hotspot identify impacted indicated infections Moran’s I Muscat Oman SARS-CoV-2 Spatial analysis spread of COVID-19 study period supplementary material System technique threshold Transmission Variability Z score zone [DOI] 10.1007/s41748-020-00194-2 PMC 바로가기 [Article Type] Original Article