Novel Use of Premixed Dialysate Bags during Water Supply Interruption in Acute Hospital Setting급성 병원 환경에서 물 공급 중단 시 사전 혼합된 투석액 백의 새로운 사용Article Published on 2020-12-092022-08-31 Journal: Kidney360 [Category] MERS, SARS, 치료제, [키워드] acute dialysis acute hospital addition Bag changes in clearance Critical dependent on dialysate dialysis dialysis solutions failure flow rate Hemodialysis hospital hyperkalemia indications Inpatient Inpatients interruption methodology mitigate MONITOR natural disasters novel occurred pandemic Patient patient safety pre-mixed dialysate problem Recognition recognize Regulation Safe SARS-CoV-2 pandemic setting supply the patient the SARS-CoV-2 Treatment Ultrafiltration Volume water water quality water quality for dialysis Water Supply [DOI] 10.34067/KID.0004762020 PMC 바로가기 [Article Type] Article
Multiple SARS-CoV-2 Introductions Shaped the Early Outbreak in Central Eastern Europe: Comparing Hungarian Data to a Worldwide Sequence Data-Matrix여러 SARS-CoV-2 도입으로 중부 동유럽 초기 발병 형성: 헝가리 데이터를 전세계 시퀀스 데이터 매트릭스와 비교Comparative Study Published on 2020-12-062022-09-10 Journal: Viruses [Category] MERS, SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome Analysis applied China clinical sample clinical samples collected Complete confirmed COVID-19 patients coronavirus coronavirus 2 COVID-19 patient disease Europe event Evolution full-length SARS-CoV-2 genome genomic sequence GISAID database Haplotype highly pathogenic human coronavirus Hungary Laboratory mechanism Multiple network analysis outbreak pandemic performed phylodynamics Phylogenetic Recognition respiratory SARS-CoV-2 SARS-CoV-2 genomes SARS-CoV-2 sequence SARS-CoV-2 sequences Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 situation the epidemic [DOI] 10.3390/v12121401 PMC 바로가기 [Article Type] Comparative Study
Toll-like receptors in sepsis-associated cytokine storm and their endogenous negative regulators as future immunomodulatory targets패혈증 관련 사이토카인 폭풍의 유료 유사 수용체 및 미래 면역 조절 표적으로서의 내인성 음성 조절자Review Published on 2020-12-012022-09-11 Journal: International immunopharmacology [Category] SARS, 유전자 메커니즘, [키워드] activate Activation acute infections Acute inflammation cells chemokines COVID-19 cytokine Cytokine storm Cytokines damage DAMPs death Diseases downstream signaling pathway downstream signaling pathways expressed generate Genetic Host host cells host cells) Immune cell immune cells Immune homeostasis immunomodulatory implicated include induction inflammatory conditions Inflammatory diseases Inflammatory response Innate Innate immunity interferons lead maintain MAMP MAMPs mechanism mechanisms mediators MODS molecular pattern multi-organ dysfunction multi-organ failure negative feedback negative feedback mechanisms neurons nitrogen non-immune organ dysfunction oxygen PAMPs pandemic pathogen Pathogens Pathways Pattern recognition pattern recognition receptor persistence pro-inflammatory mediator pro-inflammatory mediators PRRs reactive oxygen Recognition recognize released repair ROS Sepsis severe COVID-19 subject syndrome systemic inflammatory target the patient therapeutic drug TLR TLR signaling TLR signaling pathways TLRs Toll-like receptor Toll-like receptors [DOI] 10.1016/j.intimp.2020.107087 PMC 바로가기 [Article Type] Review
Lymphocyte Changes in Severe COVID-19: Delayed Over-Activation of STING?심각한 COVID-19의 림프구 변화: STING의 지연된 과활성화?Review Published on 2020-12-012022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커, [키워드] ACE2 activated Activation acute respiratory syndrome affected antigen presenting cell antigen presenting cells Aspirin autophagy B cell B cell response B cells CD147 CD26 CD4+ CD8+ CD8+ T cell cGAMP cGAS change contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cyclic cytokine cytokine secretion damages Delayed dinucleotide DNA DNA damage early stages Express expressed functional Gain of function Genes Host Human IL-6 immune cells induce infancy Infection inhibit inhibitor interferon IRF3 Last less lymphocyte Lymphocytes lymphopenia main receptor microbial NF-κB pathway Pneumonitis Recognition respiratory responsiveness SARS-CoV-2 severe coronavirus disease severe COVID-19 severe COVID-19 patient severe COVID-19 patients similarity SLC19A1 small molecule Small molecules stimulator STING T and B cell responses T cell T cells TBK1 TCR Th2 transfer triggered Vasculopathy [DOI] 10.3389/fimmu.2020.607069 PMC 바로가기 [Article Type] Review
COVID-19 detection in radiological text reports integrating entity recognition개체 인식을 통합하는 방사선 텍스트 보고서의 COVID-19 탐지Article Published on 2020-12-012022-09-11 Journal: Computers in biology and medicine [Category] SARS, 치료기술, [키워드] Accuracy approach automatic detection automatically baseline best can be used Chest Chest CT clinician Computed tomography COVID-19 Diagnosis disorder entity experiment help information input integration language likelihood lung involvement Lungs machine learning machine learning approaches mutual information Named entity recognition natural natural language natural language processing offer overcome Patient PCR test predict presenting processing provided radiological radiological finding Radiological report Recognition SVM text Text classification with COVID-19 [DOI] 10.1016/j.compbiomed.2020.104066 PMC 바로가기 [Article Type] Article
Healthy donor T cell responses to common cold coronaviruses and SARS-CoV-2감기 코로나바이러스와 SARS-CoV-2에 대한 건강한 기증자 T 세포 반응Clinical Trial Published on 2020-12-012022-09-11 Journal: The Journal of Clinical Investigation [Category] SARS, 임상, 치료기술, 치료법, 치료제, [키워드] 229E acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adaptive immunity Cell characterized circulating common cold common cold coronavirus common cold Coronaviruses coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Culture determine Donor donors ELISPOT ELISpot assay enzyme enzyme-linked immunospot exposure to had no HCoV HCoV-229E HCoV-NL63 HCoV-OC43 healthy donor Immunity immunology in vitro Infectious disease influence memory T memory T cell NL63 Novel coronavirus nucleocapsid protein Nucleocapsid proteins OC43 outcomes peptide peptide pool peptide pools peptides Recognition recognize reported response SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike protein seronegative severe acute respiratory syndrome Coronavirus Spike protein Spike proteins suggested T cell T cell response T cell responses T cells the spike protein virus [DOI] 10.1172/JCI143120 PMC 바로가기 [Article Type] Clinical Trial
Prevalence of readily detected amyloid blood clots in ‘unclotted’ Type 2 Diabetes Mellitus and COVID-19 plasma: a preliminary report'응고되지 않은' 제2형 당뇨병 및 COVID-19 혈장에서 쉽게 검출되는 아밀로이드 혈전의 유병률: 예비 보고서Original Investigation Published on 2020-11-172022-09-10 Journal: Cardiovascular Diabetology [Category] SARS, 치료기술, [키워드] addition amyloid analysed Analysis blood clot Coagulopathies Coagulopathy Comorbidity COVID-19 develop diabetes Early detection genotypic healthy indicated individual individuals Lungs nasopharyngeal swabs Pathologies pathology patients patients with COVID-19 physiological plasma preliminary report Recognition Result SARS-CoV-2 virus sensitivity severity significantly increased therapy Type Type 2 diabetes mellitus virus was collected [DOI] 10.1186/s12933-020-01165-7 PMC 바로가기 [Article Type] Original Investigation
Development of Patient-Derived Human Monoclonal Antibodies Against Nucleocapsid Protein of Severe Acute Respiratory Syndrome Coronavirus 2 for Coronavirus Disease 2019 Diagnosis중증 급성 호흡기 증후군의 뉴클레오캡시드 단백질에 대한 환자 유래 인간 단일클론 항체 개발 코로나바이러스 질병 2019 진단을 위한 코로나바이러스 2Immunology Published on 2020-11-132022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료법, 치료제, [키워드] acute respiratory syndrome coronavirus Against antibodies antibody Antigen binding can be used caused Clinical diagnosis complement conserved coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 development Diagnosis diagnosis of SARS-CoV-2 donors ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay epitope Epitopes evaluated Fab FIVE fragment of global public health Human human antibody immunogenic infected patients Infection information library nucleocapsid protein pandemic Peripheral blood phage display Recognition Research resource respiratory sandwich ELISA SARS-CoV-2 SARS-COV-2 infection screened severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spike protein Viral Viral antigen Viral detection [DOI] 10.3389/fimmu.2020.595970 PMC 바로가기 [Article Type] Immunology
Case Report: Pediatric Patient with COVID-19 and Multisystem Inflammatory Syndrome in ChildrenCOVID-19 Case Report Published on 2020-11-082022-10-31 Journal: Clinical Practice and Cases in Emergency Medicine [Category] COVID-19, [키워드] association characteristic children Coronavirus disease 2019 COVID-19 COVID-19 case ECMO extracorporeal membrane oxygenation facilitate Inflammatory Kawasaki disease morbidity pediatric Pediatric patients PMI presenting Recognition report risk stratification severe complication Shock Symptom syndrome unique with COVID-19 [DOI] 10.5811/cpcem.2020.8.48376 PMC 바로가기 [Article Type] COVID-19 Case Report
Host Receptors of Influenza Viruses and Coronaviruses—Molecular Mechanisms of RecognitionReview Published on 2020-10-062022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] caused coronavirus Coronaviruses CoV COVID-19 pandemic CoVs death detectable Epidemic Fatality rate H1N1 HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 host range host receptor human CoVs humans IAV IBV immunologically Infection infections Influenza influenza A virus influenza B Influenza virus influenza viruses knowledge Lineage mild respiratory naïve outbreak pandemic protein receptors Receptor binding receptors Recognition recorded sialyl glycans specificity spike glycoproteins spikes structures Subtypes variants virus virus variants viruses zoonotic [DOI] 10.3390/vaccines8040587 PMC 바로가기 [Article Type] Review