SARS-CoV-2 nucleocapsid – Page 19 – Communicable Diseases Research

SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas

Research

Published on 2021-02-032022-10-05
Journal: Nature metabolism [Category] 치료기술,

Time course of the sensitivity and specificity of anti-SARS-CoV-2 IgM and IgG antibodies for symptomatic COVID-19 in Japan

일본의 코로나19 증상에 대한 항SARS-CoV-2 IgM 및 IgG 항체의 민감도 및 특이도의 시간 경과

Article

Published on 2021-02-022022-09-01
Journal: Scientific Reports [Category] MERS, 진단, 치료기술, 치료법,

[키워드] anti-SARS-CoV-2 IgM Antibody test antibody tests chemiluminescent immunoassay CLIA coated with coronavirus Coronavirus infection coronavirus infection disease Course COVID-19 COVID-19 patients Cutoff cutoff value Day diagnosis of COVID-19 diagnosis of SARS-CoV-2 Diagnostic markers disease onset Diseases evaluate IgG IgG antibody IgG test IgG titers IgM IgM and IgG Infection Infectious diseases Japan less magnetic bead Magnetic beads much higher patient population Protein reported required respiratory respiratory syndrome coronavirus ROC analysis SARS-CoV-2 SARS-CoV-2 IgM SARS-COV-2 infection SARS-CoV-2 nucleocapsid sensitivity Sensitivity and specificity sera Spike protein subjects suggested symptom onset symptomatic the SARS-CoV-2 time titers Treatment
[DOI] 10.1038/s41598-021-82428-5 PMC 바로가기 [Article Type] Article

The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein

SARS-CoV-2 뉴클레오캡시드 인단백질은 RNA 및 막 관련 M 단백질과 상호 배타적인 축합물을 형성합니다.

Article

Published on 2021-01-212022-09-10
Journal: Nature Communications [Category] 치료법,

SARS-CoV-2 nucleocapsid protein undergoes liquid–liquid phase separation into stress granules through its N-terminal intrinsically disordered region

Correspondence

Published on 2021-01-212022-10-31
Journal: Cell Discovery [Category] COVID-19,

[키워드] Cell signalling immunology intrinsically N-terminal Protein SARS-CoV-2 nucleocapsid stress granule
[DOI] 10.1038/s41421-020-00240-3 PMC 바로가기 [Article Type] Correspondence

Eastern Cape Healthcare Workers Acquisition of SARS-CoV-2 (ECHAS): Cross-Sectional (Nested Cohort) Study Protocol

이스턴 케이프 의료 종사자 SARS-CoV-2(ECHAS) 획득: 횡단면(중첩 코호트) 연구 프로토콜

Protocol

Published on 2021-01-052022-09-10
Journal: International Journal of Environmental Research an [Category] 치료법,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 addition African Antenatal antibody antibody assay antibody levels Cape Chain Reaction Clinical characteristics Cluster CMIA Cohort cohort study Community community infection conducted Coronavirus-2 country COVID-19-related death cross-sectional cross-sectional study cumulative decay Department Eastern Cape Effectiveness Fatality rate finding HCW HCWs Health health facilities healthcare worker Healthcare workers highlight humoral immune response identify IgG antibodies IgG antibody immunoassay increased risk independent risk factor independent risk factors Infection Infection prevention infection rate logistic regression models longitudinal change longitudinal changes measure Microparticle offer pandemic participant polymerase chain polymerase chain reaction positive Prevention and control PROTECT Protein qualitative detection questionnaire recruited Regression model Reinfection respiratory reverse transcription reverse transcription polymerase chain reaction RT-PCR SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid SARS-CoV-2 RT-PCR SARS-CoV-2 serology SARS-CoV-2 seroprevalence second wave selected serology South South Africa tested the SARS-CoV-2 virulent women worker
[DOI] 10.3390/ijerph18010323 PMC 바로가기 [Article Type] Protocol

Rigid monoclonal antibodies improve detection of SARS-CoV-2 nucleocapsid protein

강성 단일클론 항체는 SARS-CoV-2 뉴클레오캡시드 단백질의 검출을 개선합니다

Article

Published on 2021-01-012022-09-11
Journal: mAbs [Category] 진단, 치료기술, 치료법,

[키워드] Affect antibody Antigen assembly biological phenomena complex conducted Critical Detection sensitivity diagnostics early diagnosis enzyme-linked immunosorbent enzyme-linked immunosorbent assay epidemiological studies Epidemiological study epitope Epitopes facilitate flexibility flexible IMPROVE juxtaposition lateral flow linear mAb mAbs mAbs polymerization monoclonal antibodies monoclonal antibody N-terminal domain NTD nucleocapsid nucleocapsid protein pathogen Pathogens point-of-care prevented Protein SARS-CoV-2 SARS-CoV-2 nucleocapsid scattering selective small-angle x-ray scattering. transmission electron microscopy Treatment X-ray scattering
[DOI] 10.1080/19420862.2021.1905978 PMC 바로가기 [Article Type] Article

Inhaled route and anti-inflammatory action of ivermectin: Do they hold promise in fighting against COVID-19?

이버멕틴의 흡입 경로 및 항염 작용: COVID-19와의 싸움에서 약속이 있습니까?

Article

Published on 2021-01-012022-08-31
Journal: Medical Hypotheses [Category] SARS, 신약개발, 치료법, 치료제,

Detection of breastmilk antibodies targeting SARS-CoV-2 nucleocapsid, spike and receptor-binding-domain antigens

Letter

Published on 2020-12-272022-10-31
Journal: Emerging Microbes & Infections [Category] COVID-19,

1 H, 13 C, and 15 N backbone chemical shift assignments of the C-terminal dimerization domain of SARS-CoV-2 nucleocapsid protein

Article

Published on 2020-12-032022-10-27
Journal: Biomolecular Nmr Assignments [Category] COVID-19,

[키워드] backbone binding Biomedical research C-terminal caused Community conserved coronavirus coronavirus 2 COVID-19 COVID19-NMR CTD Dimerization domain domain downstream drug target in viral independent International intrinsically involved linker N protein N-terminal RNA-binding domain NMR novel coronavirus SARS-CoV-2 NTD nucleic acid nucleocapsid nucleocapsid protein oligomerization outbreak pandemic Protein Protein druggability Replication respiratory Respiratory disease RNAs SARS-CoV-2 SARS-CoV-2 nucleocapsid Solution NMR-spectroscopy structural protein Support the N protein the SARS-CoV-2 Transcription Viral protein viral RNA genome
[DOI] 10.1007/s12104-020-09995-y PMC 바로가기 [Article Type] Article

1 H, 13 C, and 15 N backbone chemical shift assignments of the C-terminal dimerization domain of SARS-CoV-2 nucleocapsid protein

Article

Published on 2020-12-032022-10-27
Journal: Biomolecular Nmr Assignments [Category] Coronavirus, COVID-19, SARS,

[키워드] backbone binding Biomedical research C-terminal caused Community conserved coronavirus coronavirus 2 COVID-19 COVID19-NMR CTD Dimerization domain domain downstream drug target in viral independent International intrinsically involved linker N protein N-terminal RNA-binding domain NMR novel coronavirus SARS-CoV-2 NTD nucleic acid nucleocapsid nucleocapsid protein oligomerization outbreak pandemic Protein Protein druggability Replication respiratory Respiratory disease RNAs SARS-CoV-2 SARS-CoV-2 nucleocapsid Solution NMR-spectroscopy structural protein Support the N protein the SARS-CoV-2 Transcription Viral protein viral RNA genome
[DOI] 10.1007/s12104-020-09995-y PMC 바로가기 [Article Type] Article