Symptoms and risk factors for hospitalization of COVID-19 presented in primary care An exploratory retrospective study1차 진료실에서 제시한 코로나19 입원의 증상 및 위험인자 탐색적 후향적 연구Observational Study Published on 2022-02-112022-09-10 Journal: Wiener Klinische Wochenschrift [Category] COVID19(2023년), MERS, SARS, 임상, 치료기술, 치료제, [키워드] association Care conducted Course COVID-19 COVID‐19 criteria cross Data collection demographic data demographics Descriptive analyses Descriptive analysis disease exploratory Fisher’s exact test group help hospital Hospital admission hospital care Hospitalization Hospitalized identify Interpretation Intervention knowledge monitoring Most patient Most patients multiplicity number of symptom objective observational study outcome measure participant Patient Practitioner practitioners predictors primary care recording recruited Result Retrospective study risk factor Risk factors SARS-CoV‑2 sensitivity tests setting severe disease significance level supplementary material Symptom test results was performed were assessed [DOI] 10.1007/s00508-021-01992-y PMC 바로가기 [Article Type] Observational Study
Observed and predicted premature mortality in Australia due to non-communicable diseases: a population-based study examining progress towards the WHO 25X25 goalResearch Article Published on 2022-02-102022-10-28 Journal: BMC Medicine [Category] Coronavirus, COVID19(2023년), Fulltext, MERS, SARS, [키워드] age age and sex average calculated Cancer cardiovascular disease cause-specific mortality chronic respiratory disease chronic respiratory diseases condition conducted COVID-19 pandemic death declined diabete diabetes effort evaluate group highest male men and women Mortality mortality rate Non-communicable disease non-communicable diseases Observed occurred Older Poisson regression predict predicted Premature Premature mortality Probability reduction reduction in Registered Respiratory disease Result Sex sociodemographic factors supplementary material the WHO Variation WHO WHO 25X25 goal World Health Organization’ [DOI] 10.1186/s12916-022-02253-z PMC 바로가기 [Article Type] Research Article
Pulmonary vascular inflammation with fatal coronavirus disease 2019 (COVID-19): possible role for the NLRP3 inflammasomeResearch Published on 2022-02-102022-10-28 Journal: Respiratory Research [Category] COVID-19, MERS, [키워드] accompany Activation acute respiratory disease affected appear ARDS caspase causes changes in component coronavirus disease COVID-19 disease distress expression H&E histological histopathological features hyperinflammation Inflammation Injury lung Lung inflammation Lungs Mechanical ventilation mechanical ventilation microthrombi Microthrombosis NLRP3 NLRP3 inflammasome Non-COVID-19 not different outcome pathway pulmonary response Result SARS-COV-2 infection shown subject subjects supplementary material syndrome thrombosis Treatment Vascular Vascular change Vascular endothelium vascular inflammation vessel wall vessels [DOI] 10.1186/s12931-022-01944-8 PMC 바로가기 [Article Type] Research
Linked nosocomial COVID-19 outbreak in three facilities for people with intellectual and developmental disabilities due to SARS-CoV-2 variant B.1.1.519 with spike mutation T478K in the NetherlandsSARS-COV-2 변형으로 인한 지적 및 발달 장애가있는 사람들을위한 3 개의 시설에서 연결된 병원체 CovID-19 발생 B.1.1.519 네덜란드에 스파이크 돌연변이 T478K가있는Research Published on 2022-02-102022-09-10 Journal: BMC Infectious Diseases [Category] COVID19(2023년), Fulltext, MERS, SARS, 변종, [키워드] Asymptomatic attack attack rate B.1.1.519 variant Characteristics circulating variants clinical clinical information confirmed case COVID-19 infection developmental developmental disabilities died dominant Evidence Genotype Hospitalized increased risk index individual Infection prevention Infection prevention and control information Intellectual and developmental disability intrinsic measure Median viral load morbidity morbidity and mortality Mortality Netherland Netherlands no significant difference nosocomial COVID-19 notification Observed outbreak PCR Prevalence protocol reported Result SARS-CoV-2 SARS-CoV-2 variant Sequencing significant difference specimen spike mutation submitted subsequent supplementary material Support Surveillance T478K T478K spike mutation Travel vaccination against COVID-19 variant Viral [DOI] 10.1186/s12879-022-07121-y PMC 바로가기 [Article Type] Research
Hospital acquired COVID-19 infections amongst patients before the rollout of COVID-19 vaccinations, a scoping reviewResearch Published on 2022-02-102022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, COVID19(2023년), Fulltext, MERS, SARS, [키워드] Analysis applied approach article articles Asia Brazil Care Combination conducted country Coverage COVID-19 COVID-19 infection COVID-19 vaccinations Critical effective eligible English estimate Europe Evidence feasibility HAI healthcare healthcare worker high risk hospital Hospital acquired Hospital acquired infections hospitalised patient hospitalized patients identify implementation increased risk Infection infections Intervention literature North America not differ operative Operative surgery Patient patients peer-reviewed presenting prevented proportion protocols Psychiatric Public healthcare Quality ranged reduce reported Result selected supplementary material vaccination Vaccine Web of Science [DOI] 10.1186/s12879-022-07128-5 PMC 바로가기 [Article Type] Research
Seroprevalence of SARS-CoV-2 antibodies in social housing areas in Denmark덴마크의 사회 주택 지역에서 SARS-COV-2 항체의 혈청 유병률Research Article Published on 2022-02-102022-09-01 Journal: BMC Infectious Diseases [Category] COVID19(2023년), Fulltext, MERS, SARS, 진단, [키워드] 95% CI age antibodies Antibody test blood donor Blood donors can be used close contact concerning conducted Contact contact with COVID-19 COVID-19 pandemic Denmark ELISA assay female higher risk household Households IgG antibody increase in individual infected individuals Infection male National offered Older participant Participants point-of-care Population Prevalence prevalent preventive measure preventive measures questionnaire recommendations recruitment reported Result risk factor Risk factors risk ratio risk ratios SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 IgM SARS-CoV-2 seroprevalence selected seropositive Seropositivity Seroprevalence significantly higher significantly increased Social housing areas socioeconomic status supplementary material thought total Ig with COVID-19 [DOI] 10.1186/s12879-022-07102-1 PMC 바로가기 [Article Type] Research Article
Model-based patient matching for in-parallel pressure-controlled ventilationResearch Published on 2022-02-092022-10-28 Journal: BioMedical Engineering OnLine [Category] Coronavirus, COVID19(2023년), Fulltext, MERS, SARS, [키워드] addition approach Care clinician Co-ventilation COVID-19 infection criteria Decision support Effect evaluate implementation in silico information lack lung mechanical ventilator Model-based method obese patient Parallel ventilation Patient patients performed Research Respiratory mechanics Result resulting risk Safe subsequent supplementary material tested trials Ventilation Volume [DOI] 10.1186/s12938-022-00983-y PMC 바로가기 [Article Type] Research
Diagnostic performance and clinical feasibility of a novel one-step RT-qPCR assay for simultaneous detection of multiple severe acute respiratory syndrome coronaviruses다중 심각한 급성 호흡기 증후군 코로나 바이러스의 동시 검출을위한 새로운 1 단계 RT-QPCR 분석의 진단 성능 및 임상 적 타당성Original Article Published on 2022-02-092022-09-10 Journal: Archives of Virology [Category] COVID19(2023년), Fulltext, MERS, SARS, 변종, 치료기술, 치료제, [키워드] Acute respiratory infection acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis can be used caused cell culture supernatants Chain Reaction circulating variant clinical outcomes clinical sample coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CoVs Critical cross-reaction Diagnosis early diagnosis evaluated event feasibility genes encoding healthy individuals human CoV human CoVs humans IMPROVE in vitro infect Laboratory laboratory diagnosis limit of detection majority membrane mild respiratory symptoms mRNA multiplex RT-qPCR nasal swab Other other coronaviruses Other respiratory viruses patients with COVID-19 polymerase chain polymerase chain reaction Protein qPCR assay Quantitative reaction respiratory respiratory infection Respiratory samples respiratory symptoms respiratory viruses reverse transcription RNA RT-qPCR SARS-CoV-2 SARS-like CoV SARS-like CoVs SARS-related CoV severe acute respiratory syndrome Coronavirus sputum samples supplementary material TCID Transmission zoonotic origin [DOI] 10.1007/s00705-022-05383-0 PMC 바로가기 [Article Type] Original Article
Cost-effectiveness and cost-utility evaluation of individual vs. group transdiagnostic psychological treatment for emotional disorders in primary care (PsicAP-Costs): a multicentre randomized controlled trial protocolStudy Protocol Published on 2022-02-092022-10-27 Journal: BMC Psychiatry [Category] Coronavirus, COVID19(2023년), Fulltext, MERS, SARS, [키워드] Administered anxiety disorders approach baseline Brief psychological treatments Care Clinical practice collected contribute Cost-benefit analysis COVID-19 pandemic Depression disorder effective emotional Emotional disorders group therapy Health health system help implementation less Mental disorder mental health problems Mild moderate multicentre outcome performed prevalent primary care protocol psychological treatment psychologist Psychotropic drugs Quality of life Randomized Randomized controlled trial recruited Regulation Research resource Somatoform disorders Spain Spanish supplementary material Symptoms Tau therapy Transdiagnostic therapy treated Treatment Trial used to calculate [DOI] 10.1186/s12888-022-03726-4 PMC 바로가기 [Article Type] Study Protocol
Transcriptional landscape of circulating platelets from patients with COVID-19 reveals key subnetworks and regulators underlying SARS-CoV-2 infection: implications for immunothrombosisResearch Published on 2022-02-092022-11-01 Journal: Cell & Bioscience [Category] COVID-19, [키워드] acute respiratory syndrome affected aggregation Analysis binding Cell circulating platelet Clinical outcome Coagulopathy coding coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 patients COVID-19 progression Critical eight energy metabolism feature healthy donors Hemostasis immune response immunothrombosis implication increased mortality Interaction involved mechanism molecular mechanism multiple organ failure Pathways patients with COVID-19 performed Platelet platelet activation Platelets promoted Protein provided regulate Result reveal risk RNA RNA Polymerase II RNA sequencing SARS-CoV-2 SARS-COV-2 infection severe COVID-19 disease severity significantly subunit supplementary material therapeutic strategy thrombosis thrombotic complication thrombus formation transcription factor transcriptional Transcriptome upstream with COVID-19 [DOI] 10.1186/s13578-022-00750-5 PMC 바로가기 [Article Type] Research