A network-informed analysis of SARS-CoV-2 and hemophagocytic lymphohistiocytosis genes’ interactions points to Neutrophil extracellular traps as mediators of thrombosis in COVID-19SARS-CoV-2와 hemophagocytic lymphohistiocytosis 유전자의 상호 작용에 대한 네트워크 기반 분석은 COVID-19의 혈전증 매개체로서 호중구 세포외 트랩을 가리킵니다.Research Article Published on 2021-03-082022-09-10 Journal: PLoS Computational Biology [Category] SARS, 유전자 메커니즘, [키워드] abnormal coagulation acting Adults Algorithm Algorithms Analysis approach children circulating co-morbidities co-morbidity Coagulation concert condition consequence COVID-19 described disease Diseases Endothelium environmental condition environmental conditions Epidemic extracellular trap extracellular traps favor feature Genetic genetic information H1N1 H1N1 influenza hematologic hemophagocytic lymphohistiocytosis HLH Host host gene hyperinflammation Hypothesis identify Immune cell immune cells increase increased risk individual inflammatory condition inflammatory conditions inflammatory process inflammatory signal inflammatory signals Influenza information Interaction life-threatening likelihood manuscript mechanism mediators Metabolic disorders morbidities NET NETs network neutrophil Neutrophils Pathogenesis pathogenic pathway Pathways potential mechanism potential molecular predict presenting problem Pulmonary thromboembolism regulate responsible risk SARS-CoV-2 serious complication severe COVID-19 severely ill patient severely ill patients similarities similarity tested Thromboembolism thrombosis thrombotic thrombotic complication Thrombotic complications trajectory underlying condition underlying conditions vascular thrombosis Viral protein Viral proteins [DOI] 10.1371/journal.pcbi.1008810 PMC 바로가기 [Article Type] Research Article
COVID-19 and pneumatosis intestinalis: An early sign of intestinal ischemiaComment Published on 2021-03-012023-07-11 Journal: Digestive and liver disease : official journal of [Category] SARS, [키워드] bowel Necrosis SARS-CoV2 Thromboembolism [DOI] 10.1016/j.dld.2020.10.036 PMC 바로가기 [Article Type] Comment
Aminotransferases disorders associated with venous thromboembolic events in patients infected with COVID-19COVID-19에 감염된 환자의 정맥 혈전색전증과 관련된 아미노전이효소 장애Article Published on 2021-03-012022-09-11 Journal: Annals of hepatology [Category] MERS, SARS, 바이오마커, [키워드] Admission Aminotransferase Aminotransferases disorders analyzed Anticoagulant AST balance collected Comorbidities Comorbidity COVID-19 COVID-19 infection COVID-19 pandemic curative Day demographics Direct Direct oral anticoagulant disorder disorders distance DOAC DOACs eight elevated Elevated AST and ALT enoxaparin evaluate event Evidence Follow-up heparin incidence infected patient infected patients infected with COVID-19 laboratory parameter Laboratory parameters liver Liver disorders low molecular weight low molecular weight heparin lower limb lower limbs monitoring normalization outbreak Patient patients Perspective reported Retrospective study Thromboembolism treated venous thromboembolic Venous Thromboembolism VTE was performed [DOI] 10.1016/j.aohep.2020.10.002 PMC 바로가기 [Article Type] Article
High prevalence of occult thrombosis in cases of mild/moderate COVID-19경증/중등도 COVID-19의 경우 잠재성 혈전증의 높은 유병률Article Published on 2021-03-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 치료기술, [키워드] analyzed biochemical blood test blood tests clinical manifestations Coagulation coagulation test Computed tomography Computed tomography pulmonary angiography COVID-19 COVID-19 pneumonia CPTA CTPA distal Doppler ultrasound DVT evaluate Features incidence Inflammatory Laboratory laboratory examinations LDH limb lung Lungs Mild/moderate COVID-19 normal range parameter Patient patients with COVID-19 performed Pneumonia positive Prevalence Prognosis pulmonary angiography Research screened Screening Severe case severe cases the patient Thromboembolism thrombosis thrombotic Thrombotic complications Venous Thromboembolism VTE WBC [DOI] 10.1016/j.ijid.2020.12.042 PMC 바로가기 [Article Type] Article
Where There’s Smoke, There’s Fire: A Case Report of Turbulent Blood Flow in Lower Extremity Point-of-care Ultrasound in COVID-19COVID-19 Case Report Published on 2021-02-232022-10-31 Journal: Clinical Practice and Cases in Emergency Medicine [Category] COVID-19, [키워드] anticoagulation blood flow Coronavirus disease 2019 COVID-19 COVID-19 patient Deep venous thrombosis disease severity DVT endothelial injury Evidence extremity Flow high risk increased risk Inflammation Lower marker Microvascular damage pathology pathophysiological mechanisms Patient patients with COVID-19 Physicians Point-of-Care ultrasound predict proximal reactive report smoke Thromboembolism thrombosis Treatment Ultrasound venous Venous Thromboembolism vessel VTE [DOI] 10.5811/cpcem.2020.10.48809 PMC 바로가기 [Article Type] COVID-19 Case Report
The incidence of pulmonary thromboembolism in COVID-19 patients admitted to the intensive care unit: a meta-analysis and meta-regression of observational studiesResearch Published on 2021-02-222022-10-30 Journal: Journal of Intensive Care [Category] COVID-19, [키워드] 95% CI Analysis anticoagulation average Characteristics Cochran’s Q test complication of COVID-19 Coronavirus disease 2019 COVID-19 COVID-19 patient Critical care Critically ill patient database demographics heterogeneity ICU incidence Infection intensive care intensive care unit male Meta-analysis meta-regression objective observational study Patient performed Prophylactic proportion prothrombotic state Pulmonary thromboembolism reported Result searched supplementary material Thromboembolism was performed [DOI] 10.1186/s40560-021-00535-x PMC 바로가기 [Article Type] Research
In vitro and In silico Models to Study SARS-CoV-2 Infection: Integrating Experimental and Computational Tools to Mimic “COVID-19 Cardiomyocyte”Physiology Published on 2021-02-172022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] “COVID-19 acute coronary syndromes addition adopted Affect animal model Arrhythmias cardiac adverse events cardiac disease cardiac function Cardiomyocytes caused Characteristics clinically Comorbidity contribute COVID-19 death disease dissemination drug drug treatments Effect effort electrolyte imbalance Gender Health hiPSC-CMs Immunological response in silico in vitro Infection mechanism MIMIC MINI Model modeling myocardial injury Numerous organ over pathophysiology Perspective pluripotent stem cells predict progression question reported respiratory review SARS-CoV-2 SARS-COV-2 infection the disease Thromboembolism treat Treatment virus [DOI] 10.3389/fphys.2021.624185 PMC 바로가기 [Article Type] Physiology
Diagnostic imaging in COVID-19 pneumonia: a literature reviewCOVID-19 폐렴의 진단 영상: 문헌 검토Review Published on 2021-02-152022-09-10 Journal: Journal of Ultrasound [Category] MERS, SARS, 진단, 치료기술, [키워드] 2019-nCoV acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 approach ARDS changes China Computed tomography Contact coronavirus COVID-19 CT diagnosis of COVID-19 disease Disease progression Disinfection early diagnosis false negatives gold gold standard Health Organization HRCT ICUs identify intensive care unit intensive care units interstitial literature review manifestation Pneumonia pulmonary involvement Pulmonary thromboembolism radiologist Radiologists related disease respiratory respiratory distress Respiratory failure SARS-CoV-2 sensitivity severe acute respiratory syndrome Coronavirus Swab test syndrome Thromboembolism Triage Ultrasound US World Health Organization Wuhan [DOI] 10.1007/s40477-021-00559-x PMC 바로가기 [Article Type] Review
Thrombotic complications in 2928 patients with COVID-19 treated in intensive care: a systematic reviewArticle Published on 2021-02-142022-10-30 Journal: Journal of Thrombosis and Thrombolysis [Category] COVID-19, MERS, [키워드] addressed Anticoagulant anticoagulation clinical suspicion Cohort Complication conducted coronavirus Critical care Deep venous thrombosis demographics Diagnosis dose Embolism high mortality hospitalized patients ICU identify incidence Intensive intensive care management observational study occurred outcomes Patient patients patients with COVID-19 Prevalence Prospective trial prothrombotic state recommendation reported Severe COVID-19 Infection severe disease significantly higher supplementary material systematic review Thromboembolism Thromboprophylaxis thrombosis thrombotic complication Thrombotic complications Thrombotic events treated venous Venous thrombosis [DOI] 10.1007/s11239-021-02394-7 PMC 바로가기 [Article Type] Article
Targeting the SARS-CoV-2 3CL pro and NO/cGMP/PDE5 pathway in COVID-19: a commentary on PDE5 inhibitorsCommentary Published on 2021-02-122022-10-31 Journal: Future Cardiology [Category] COVID-19, MERS, SARS, [키워드] 3CL pro 3CLpro COVID-19 NO/cGMP pathway PDE5 PDE5 inhibitor PDE5 inhibitors SARS-CoV-2 Sildenafil Tadalafil targeting the SARS-CoV-2 Thromboembolism [DOI] 10.2217/fca-2020-0201 PMC 바로가기 [Article Type] Commentary