COVID-19 ARDS patient – Page 2 – Communicable Diseases Research

Closed-Loop Versus Conventional Mechanical Ventilation in COVID-19 ARDS

Original Research

Published on 2021-06-082022-10-29
Journal: Journal of Intensive Care Medicine [Category] COVID-19, MERS, SARS,

Serious complications in COVID-19 ARDS cases: pneumothorax, pneumomediastinum, subcutaneous emphysema and haemothorax

Original Paper

Published on 2021-06-082022-11-01
Journal: Epidemiology and Infection [Category] COVID-19, MERS, SARS,

[키워드] acute respiratory distress Admission alveolar injury ARDS ARDS patient Blood cause caused Complication coronavirus COVID-19 COVID-19 ARDS patient criteria Diagnosis emphysema incidence increase Infection intensive care lactate dehydrogenase life-threatening mechanical ventilation morbidity Mortality mortality rate no statistical difference Novel coronavirus occurred onset of symptoms pathophysiology Patient patients PEEP Pneumomediastinum Pneumothorax Positive end-expiratory pressure Prone position reducing mortality risk factor SARS CoV-2 significantly statistically significant syndrome treated Treatment two group with COVID-19
[DOI] 10.1017/S0950268821001291 PMC 바로가기 [Article Type] Original Paper

IL-1 Receptor Antagonist Anakinra in the Treatment of COVID-19 Acute Respiratory Distress Syndrome: A Retrospective, Observational Study

Observational Study

Published on 2021-04-012022-10-05
Journal: Journal of immunology (Baltimore, Md. : 1950) [Category] SARS, 임상,

Effect of dexamethasone in patients with ARDS and COVID-19 – prospective, multi-centre, open-label, parallel-group, randomised controlled trial (REMED trial): A structured summary of a study protocol for a randomised controlled trial

ARDS 및 COVID-19 환자에서 덱사메타손의 효과 – 전향적, 다기관, 공개 라벨, 병렬 그룹, 무작위 대조 시험(REMED 시험): 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2021-03-012022-09-10
Journal: Trials [Category] SARS, 임상, 치료기술,

[키워드] (C-reactive protein 24 hour 24 hours administration adrenal gland Adult patients Adverse adverse events age alcohol allergy allocation Antigen ARDS ARDS patients ARMS assumed Barthel Index benzyl alcohol Berlin Berlin criteria Blinding Block randomisation Brazil Breastfeeding C-reactive protein calculated can be used Cardiac arrest Care carried case report form CCI Charlson Comorbidity Index Chemotherapy clinical Comorbidity comparator completion condition conducted consequence Contraception control group Corticosteroid Corticosteroids COVID-19 COVID-19 ARDS patient criteria CRP current Czech Republic Day decision defined detect Dexamethasone dexamethasone 6 mg diagnosed dissemination dose doses Dynamics eCRF Effect Effectiveness Efficacy and safety electronic case report form element eligible Endpoint enrolled enrolment EudraCT evaluate event expected exploratory Factor followed by French gastrointestinal bleeding HFNC hospital hospital discharge Hospital stay hypersensitivity Hypothesis ICU ICU admission ICUs Identifier Immunosuppression immunosuppressive drug immunosuppressive drugs Independence independent independent of Infection infections Inflammatory infusion intensive care unit intensive care units Intervention intervention group intractable intravenously intubate intubation investigational medicinal product investigator investigators Laboratory life malignancy marker mechanical ventilation medical history moderate moderate to severe Mortality nasal nasal cannula number objective observational study once daily Open-label open-label trial outcome oxygen Oxygen therapy PaO parallel-group participant Participation Patient patients with ARDS patients with moderate performed power power of 80% Pragmatic Pregnancy present primary efficacy endpoint primary endpoint protocol Quality of life randomisation randomised randomised controlled trial receive recruitment Registered routine clinical practice RT-PCR Sample size scale secondary Secondary endpoints Septic shock sequence severe ARDS sexual abstinence solution Standard deviation statistical analysis statistician status Stratification stratified Study protocol superinfection supplementary material systemic systemic corticosteroids thrombotic Thrombotic complications title Treatment treatment arm Trial Trial registration two-sided type I type I error university hospital Ventilation ventilator-free day Ventilator-free days Version VFD website WHO
[DOI] 10.1186/s13063-021-05116-9 PMC 바로가기 [Article Type] Letter

Risk factors analysis of COVID-19 patients with ARDS and prediction based on machine learning

Article

Published on 2021-02-032022-10-04
Journal: Scientific Reports [Category] MERS, 바이오마커, 임상,

[키워드] Accuracy age Analysis ARDS ARDS patient AST AUC biochemical build Care caused China Clinical characteristics Clinical data clinical feature clinical manifestation collected Comorbidity consolidation cough COVID-19 COVID-19 ARDS patient COVID-19 patient COVID-19 patients CRP deep learning-based method develop diagnostic distress Epidemiology Factor Health hypertension indicated Infectious disease LDH lung Lymphocyte count machine learning algorithm mild patient NLR Older Patient predict Predictive medicine Probability Region resources responsible Result Risk factors secondary bacterial infection Sensitivity and specificity severe COVID-19 significantly strongly related susceptible syndrome the median ventilator were used
[DOI] 10.1038/s41598-021-82492-x PMC 바로가기 [Article Type] Article

Surfactant therapy for COVID-19 related ARDS: a retrospective case–control pilot study

Research

Published on 2021-01-182022-10-28
Journal: Respiratory Research [Category] COVID-19, MERS,

[키워드] acute respiratory distress acute respiratory distress syndrome administration Analysis ARDS ARDS patient Care cause comparable COVID-19 COVID-19 ARDS patient COVID-19 ARDS patients COVID-19 pandemic Cox regression death deplete dose Efficacy Evidence examined feasibility feasible FIVE Health lung mechanical ventilation mechanical ventilation duration Mortality not significant off-label pandemic Patient patients with COVID-19 PCR positive performed pilot study positive randomized clinical trial receiving reduce mortality reduction Result retrospective Safe subject Support supportive care surfactant Surfactant replacement therapy syndrome therapy for COVID-19 Treatment Ventilation
[DOI] 10.1186/s12931-020-01603-w PMC 바로가기 [Article Type] Research

Clinical features, ventilatory management, and outcome of ARDS caused by COVID-19 are similar to other causes of ARDS

Observational Study

Published on 2020-12-012022-10-05
Journal: Intensive care medicine [Category] Fulltext, MERS, 임상,

[키워드] 28-day mortality 95% CI acute respiratory distress syndrome affected analysed ARDS ARDS patient baseline Berlin criteria blocking agent cause caused Characteristics clinical Clinical features Clinical outcome Complete Compliance coronavirus COVID-19 COVID-19 ARDS patient COVID-19 ARDS patients COVID-19 patient defined distress driving examined feature Features ICUs intensive care unit invasive Invasive mechanical ventilation IQR lung-protective ventilation management Mechanical mechanical ventilation mechanically ventilated mechanically ventilated patient median Mild moderate multicenter nasal non-COVID-19 ARDS patient non-COVID-19 ARDS patients observational study outcome Patient patients Pharyngeal swab Positive end-expiratory pressure predicted Prone position Respiratory system risk SARS-COV-2 infection severe ARDS severity Spanish specimens value ventilatory Volume were used with COVID-19
[DOI] 10.1007/s00134-020-06192-2 PMC 바로가기 [Article Type] Observational Study

Spontaneous hemothorax in 4 COVID-19 ARDS patients on VV-ECMO revealing pulmonary artery aneurysms

Research Letter

Published on 2020-11-062022-11-01
Journal: Critical Care [Category] Coronavirus, SARS,

[키워드] Aneurysm COVID-19 ARDS patient Hemothorax Spontaneous VV-ECMO
[DOI] 10.1186/s13054-020-03359-7 PMC 바로가기 [Article Type] Research Letter

Combining lung ultrasound and Wells score for diagnosing pulmonary embolism in critically ill COVID-19 patients

중환자 COVID-19 환자의 폐색전증 진단을 위해 폐 초음파와 Wells 점수 결합

Article

Published on 2020-11-032022-09-12
Journal: Journal of Thrombosis and Thrombolysis [Category] 진단,

[키워드] addition ARDS ARDS patient ARDS patients AUC calculated Combination Computed tomography Computed tomography pulmonary angiography consolidation consolidations COVID-19 COVID-19 ARDS patient COVID-19 patient critical-ill patient critical-ill patients Critically ill CTPA detectable diagnosing diagnostic diagnostics enrolled evaluated gold gold standard ICU inclusion criteria lung Lung ultrasound Patient patients patients with COVID-19 patients with PE predicted Probability pulmonary angiography Pulmonary embolism SARS-CoV2 sensitivity significantly higher specificity subpleural supplementary material utility was used well Wells score with COVID-19
[DOI] 10.1007/s11239-020-02323-0 PMC 바로가기 [Article Type] Article

CXCL10 could drive longer duration of mechanical ventilation during COVID-19 ARDS

Research

Published on 2020-11-022022-11-01
Journal: Critical Care [Category] COVID-19,

[키워드] acute respiratory distress syndrome alarmin alveolar alveolar cell ARDS ARDS patients Biomarker Bronchoalveolar lavage CCL5 CD40 ligand cell-free mitochondrial DNA clinical Concentration concentrations confounders correlated correlation COVID-19 COVID-19 ARDS patient COVID-19 ARDS patients CXCL-10 CXCL1 CXCL10 CXCL2 DNA dysregulated immune response EGF elevated epithelial lining etiology evaluated feature GM-CSF granzyme B host response IL-10 IL-1β IL-8 immune response Inflammatory inflammatory mediator involved lung mechanical ventilation mitochondrial mitochondrial DNA no difference Non-COVID-19 outcome Pathogenesis plasma predict required Result SARS-CoV-2 significantly systemic inflammation targeting Therapeutic approach TRAIL two groups unique Ventilator-free days Viral load were measured
[DOI] 10.1186/s13054-020-03328-0 PMC 바로가기 [Article Type] Research