Delta neutrophil index and C-reactive protein: a potential diagnostic marker of multisystem inflammatory syndrome in children (MIS-C) with COVID-19델타 호중구 지수 및 C 반응성 단백질: COVID-19가 있는 어린이(MIS-C)의 다기관 염증 증후군의 잠재적 진단 마커Observational Study Published on 2022-02-012022-09-11 Journal: European journal of pediatrics [Category] MERS, 바이오마커, 임상, [키워드] 113 patient 113 patients Absolute lymphocyte count absolute neutrophil count albumin ALC Analysis ANC C-reactive protein can be used children circulating clinician control group correlation COVID COVID-19 CRP cutoff value Delta Delta neutrophil index determine Diagnosis diagnostic Diagnostic marker DNI elevated evaluate evaluated fraction granulocyte Granulocytes healthy controls Hemogram hyperinflammation immature Infection Inflammation Inflammatory Laboratory life-threatening lymphocyte marker Mild MIS MIS-C moderate multisystem inflammatory syndrome in children Negative predictive value neutrophil observational study Patient Platelet Platelet count platelet counts Positive predictive value Predictive value reflect retrospective sedimentation sensitivity serum severity sodium specificity statistically significant syndrome were recorded with COVID-19 [DOI] 10.1007/s00431-021-04281-y PMC 바로가기 [Article Type] Observational Study
Lymphopenia as a Predictor for Adverse Clinical Outcomes in Hospitalized Patients with COVID-19: A Single Center Retrospective Study of 4485 CasesArticle Published on 2022-01-282022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% CI 95% confidence interval Absolute lymphocyte count Admission Adverse adverse clinical outcomes adverse outcome adverse outcomes age center characteristic clinical clinical outcomes Comorbidities COVID-19 cubic spline determine dialysis expressed Gender hospital hospitalized COVID-19 patients ICU admission in-hospital mortality incidence increase in Invasive mechanical ventilation laboratory-confirmed Lymphocyte count lymphopenia Non-linear relationship Odds ratio outcome outcomes Patient patients with COVID-19 predict predictive power receiver operating characteristic curves restricted cubic splines retrospective risk was performed [DOI] 10.3390/jcm11030700 PMC 바로가기 [Article Type] Article
Red Blood Cell Distribution Width in Hospitalized COVID-19 PatientsMedicine Published on 2022-01-072022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95%CI Absolute lymphocyte count acute respiratory syndrome age Anemia association body mass index caused chronic obstructive Clinical outcome confounder Coronary artery disease Coronavirus-2 COVID-19 COVID-19 patient defined Diabetes Mellitus Diseases elevated ferritin hospitalized COVID-19 hospitalized COVID-19 patient hypertension in-hospital mortality increased risk Lactate Length of stay LOS mechanical ventilation median morbidity and mortality Mortality outcome Prevalence Primary outcome pulmonary disease Red Red cell distribution width (RDW) remained risk SARS-CoV-2 Secondary outcomes Septic shock Sex significantly increased width [DOI] 10.3389/fmed.2021.582403 PMC 바로가기 [Article Type] Medicine
Pre-Existing Lymphopenia Increases the Risk of Hospitalization and Death after SARS-CoV-2 InfectionArticle Published on 2022-01-042022-10-30 Journal: Infectious Disease Reports [Category] COVID-19, [키워드] 95%CI Absolute lymphocyte count age conducted COVID-19 database death determine female General population hospital discharge Hospitalization immunosuppressive therapies increase infected with SARS-CoV-2 information Laboratory logistic regression model Lymphocytes lymphopenia lymphopenic male management Older Patient patients protective factor provide remained retrospective cohort study risk risk factor risk of COVID-19 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positivity severe COVID-19 severity severity of COVID-19 Sex subject were used [DOI] 10.3390/idr14010003 PMC 바로가기 [Article Type] Article
Humoral and T-cell responses to SARS-CoV-2 vaccination in multiple sclerosis patients treated with ocrelizumab오크렐리주맙으로 치료받은 다발성 경화증 환자에서 SARS-CoV-2 백신 접종에 대한 체액 및 T 세포 반응Article Published on 2022-01-012022-09-11 Journal: Multiple sclerosis and related disorders [Category] MERS, SARS, 진단, 치료기술, [키워드] Absolute lymphocyte count adaptive Adaptive Biotechnology age analyzed anti-CD20 therapy Anti-SARS-CoV-2 S antibodies antibody Antibody Response B and T-cell BMI CD19 characterized chemotherapeutic agents cohort study comparator conducted coronavirus coronavirus vaccine COVID COVID-19 COVID-19 epidemic Descriptive statistics detectable determine did not produce Efficacy Elecsy Eligible patients enrolled Enrollment evaluate Fisher Fisher's exact test had no humoral Humoral response IgG immune response immunoassay immunogenicity Immunoglobulin Immunoglobulin G immunosuppressive impair Infection likelihood lymphocyte Multiple multiple sclerosis Natalizumab negative antibody response no correlation Ocrelizumab Patient patients patients treated positive positive antibody response post vaccination Prevent producing question raise reduce Research response Roche SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 vaccination severity Sex shown single center T-cell T-cell Response T-cell responses Test the antibody response treated Treatment vaccination Vaccine vaccine immunogenicity variable was performed were excluded Wilcoxon rank sum [DOI] 10.1016/j.msard.2021.103382 PMC 바로가기 [Article Type] Article
Susceptibility of ABO blood group to COVID-19 infections: clinico-hematological, radiological, and complications analysis4800 Published on 2021-12-302022-10-30 Journal: Medicine [Category] COVID-19, SARS, [키워드] abnormality ABO ABO blood group Absolute lymphocyte count Admitted Patient age Analysis Asymptomatic Blood Blood Group clinical information commenced Community Complication Computed tomography conducted COVID-19 COVID-19 disease COVID-19 pandemic COVID-19 patients demographic disease disease manifestation distribution Evidence Faisal Glucose groups hematological hematological parameters Hospitalized hospitalized COVID-19 patient IgA incidence indicate indicated individual Infection infections information intensive care Jeddah King Laboratory majority one-way ANOVA test outcome parameters Patient pharyngeal Prognosis progression protocols radiological Research retrospective cohort study Saudi Arabia Shortness of breath specialist statistically statistically significant difference study participant susceptibility Symptom Symptoms the mean upper respiratory tract X-ray [DOI] 10.1097/MD.0000000000028334 PMC 바로가기 [Article Type] 4800
Association of Peripheral Blood Parameters With Outcomes of COVID-19 Infection in a Tertiary Care Setting of Eastern India: An Institute-Based StudyInternal Medicine Published on 2021-12-272022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Absolute lymphocyte count absolute neutrophil count acute respiratory syndrome Admission AEC affected age ALC analyzed ANC association Blood blood sample caused Characteristics clinical symptom clinician Coagulation Comorbidity complete blood count conducted confirmed cases coronavirus COVID-19 D- dimer D-dimer death discharge disease Dyspnea eosinophil epidemiological Gender help hematological hypertension ICU ICU patient India inflammatory process information intensive care Liver disease Lymphocytes male-to-female ratio manifestation material Mortality Neutrophil-to-lymphocyte ratio Neutrophils NLR notable outcome outcomes pandemic parameter peripheral positive predict previous study progression reduce mortality Result risk RT-PCR SARS-CoV-2 setting shown statistical analysis study population Tertiary the disease [DOI] 10.7759/cureus.20745 PMC 바로가기 [Article Type] Internal Medicine
Combined Blood Indexes of Systemic Inflammation as a Mirror to Admission to Intensive Care Unit in COVID-19 Patients: A Multicentric StudyResearch Article Published on 2021-12-132022-10-31 Journal: Journal of Epidemiology and Global Health [Category] COVID-19, MERS, SARS, [키워드] Absolute lymphocyte count acute respiratory distress Admission AISI ALC AMC Blood Cell Combined COVID-19 COVID-19 patient COVID-19 patients CRP cut-off value D-dimer death Egypt elevated groups Health hematological highest ICU ICU admission independent predictor index Inflammatory response intensive care intensive care unit less leucocyte lymphocyte mechanism Mirror multivariate logistic regression neutrophil non-ICU oxygen pandemic patients with COVID-19 Platelet pro-inflammatory Result sensitivity severity SII specificity Spread supplementary material survival syndrome systemic systemic immune-inflammation index systemic inflammation systemic inflammatory response Total [DOI] 10.1007/s44197-021-00021-5 PMC 바로가기 [Article Type] Research Article
The inflammatory biomarkers profile of hospitalized patients with COVID-19 and its association with patient’s outcome: A single centered studyCOVID-19를 가진 입원 환자의 염증성 바이오 마커 프로파일 및 환자의 결과와의 연관성 : 단일 중심 연구Research Article Published on 2021-12-022022-09-10 Journal: PLoS ONE [Category] 바이오마커, [키워드] Absolute lymphocyte count acute respiratory distress acute respiratory distress syndrome addition Admission ALC Analysis ARDS association C-reactive protein classical Clinical characteristics Clinical course Clinical outcome Cohort correlation count COVID-19 COVID-19 illness COVID-19 patient COVID-19 severity Critical CRP D-dimer death direction disease disease severity Dubai ferritin help hospitalized patient hyper-inflammatory response ICU ICU admission IMPROVE incidence Infection Inflammation Inflammatory biomarker inflammatory biomarkers Inflammatory marker inflammatory markers Injury intensive care intensive care unit investigated Kuwait laboratory biomarker laboratory biomarkers Lactate lactate dehydrogenase LDH lymphocyte lymphopenia marker multiple organs dysfunction neutrophil Neutrophils organ outcome pandemic Pathogenesis Patient patient cohort patient’s death PCT predict Predictive Predictive value procalcitonin resource respiratory respiratory distress Respiratory distress syndrome SARS-CoV-2 Stratification syndrome the disease the patient Therapeutic approach triggered turn Ventilation ventilator virus WBC white cell with COVID-19 [DOI] 10.1371/journal.pone.0260537 PMC 바로가기 [Article Type] Research Article
Case Report: Clinical Features of a COVID-19 Patient With CirrhosisMedicine Published on 2021-11-262022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Absolute lymphocyte count absolute neutrophil count acute respiratory syndrome addition Affect alpha-2b Asymptomatic bilateral lung bilateral lungs Chest China cirrhosis clinical clinical feature clinician coronavirus Coronavirus disease 2019 cough COVID-19 COVID-19 patient Cured patient discharged disease Fever global pandemic homeostatic hospital immune system impair indicated Infection Inflammation injection Interaction interferon liver Patient PCR plasma polymerase chain positive preexisting comorbidity remained reported reverse transcription Ritonavir rRT-PCR SARS-CoV-2 shown systemic immune response Tablet tested the patient therapeutic effect treated Treatment WBC White blood cell Wuhan [DOI] 10.3389/fmed.2021.678227 PMC 바로가기 [Article Type] Medicine