ACE2 proteins – Page 2 – Communicable Diseases Research

Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates

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Published on 2020-09-082022-10-29
Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, MERS, SARS,

[키워드] accelerated ACE2 ACE2 proteins ACE2 sequence acute respiratory syndrome addition Amino acid amino acid change Analysis animal model assist binding Care category change coding sequence Comparative genomics coronavirus correlated COVID-19 dataset disrupt enzyme Evolution Frequency high risk highest Host host range Human Lineage main receptor mammal mammals medium Novel coronavirus outbreak pandemic predicted Protein receptor reduce residue risk SARS-CoV-2 SARS-COV-2 infection scrutiny sensitivity Significance significantly species conservation Spike protein Structural analysis susceptible the SARS-CoV-2 Transmission unique variant Vertebrate
[DOI] 10.1073/pnas.2010146117 PMC 바로가기 [Article Type] 530