An impedimetric biosensor for COVID-19 serology test and modification of sensor performance via dielectrophoresis force유전영동력을 통한 센서 성능 수정 및 COVID-19 혈청학 테스트를 위한 방해계 바이오센서Article Published on 2022-10-012022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-S antibody antibody Antibody detection Antibody test assistance AuNP binding buffer causative agent caused Concentration conjugate coronavirus coronavirus disease Coronavirus disease 2019 COVID COVID-19 COVID-19 antibody COVID-19 serology test described detect Dielectrophoresis force digit faster gold Gold interdigitated electrodes Gold nanoparticles human sera IDE immunization impedance Impedimetric biosensor. limit of detection Modification morbidity and mortality non-specific phenomenon point-of-care solution Protein purified reached responses SARS-CoV-2 secondary antibody sensitivity sensor sera serology serology test serology tests serum severe acute respiratory syndrome Coronavirus Spectroscopy spike the disease therapeutic time-consuming [DOI] 10.1016/j.bios.2022.114476 PMC 바로가기 [Article Type] Article
Omicron (BA.1) and sub-variants (BA.1.1, BA.2, and BA.3) of SARS-CoV-2 spike infectivity and pathogenicity: A comparative sequence and structural-based computational assessmentSARS-CoV-2 스파이크 감염성 및 병원성의 오미크론(BA.1) 및 하위 변이체(BA.1.1, BA.2 및 BA.3): 비교 시퀀스 및 구조 기반 계산 평가Article Published on 2022-10-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 binding acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis angiotensin BA.1 BA.2 BA.3 BA1.1 bind binding affinity bronchial cells computational tool computational tools contribute contributing to coronavirus COVID-19 Deleterious domain Effectiveness electrostatic expressed Factor hACE2 higher affinity human ACE2 human Angiotensin-converting enzyme Human angiotensin-converting enzyme 2 hydrogen hydrogen bonds indicate Interaction K417N less lineages Lower respiratory tract lung mutated Mutation mutations N-terminal domain N501Y negative NTD omicron Omicron variant pathogenicity positive predicted Q498 RBD RBM receptor receptors residue residues Salt Bridge SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2. sequence severe acute respiratory syndrome Coronavirus significantly Spike protein Spread surface potential T478K the RBD the spike protein thought Transmission transmission potential variant variants wild-type [DOI] 10.1002/jmv.27927 PMC 바로가기 [Article Type] Article
Comparative effectiveness and durability of COVID-19 vaccination against death and severe disease in an ongoing nationwide mass vaccination campaign진행중인 전국적인 대규모 예방접종 캠페인에서 COVID-19 사망 및 중증 질환에 대한 예방접종의 비교 효과 및 지속성Article Published on 2022-10-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] 95% confidence interval Active surveillance acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Ad26 Ad26.COV2.S adjusted age all age groups approved BNT162b2 ChAdOx1 ChAdOx1 nCoV-19 Cohort Cohort studies Comparative coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccination COVID-19 vaccines death dose doses Effectiveness effort immunogenicity intubation mass vaccination morbidity Mortality mRNA mRNA-1273 National of BNT162b2 offer offered pandemic prevented reduce registry data remained SARS-CoV-2 severe disease study period vaccinate vaccination Vaccine vaccine effectiveness. variant variants waned were used [DOI] 10.1002/jmv.27934 PMC 바로가기 [Article Type] Article
Antiviral efficacy of selective estrogen receptor modulators against SARS-CoV-2 infection in vitro and in vivo reveals bazedoxifene acetate as an entry inhibitor시험관 내 및 생체 내에서 SARS-CoV-2 감염에 대한 선택적 에스트로겐 수용체 조절제의 항바이러스 효능은 진입 억제제로서 바제독시펜 아세테이트를 나타냅니다Article Published on 2022-10-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 신약개발, 치료제, [키워드] Acetate acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-SARS-CoV-2 antiviral efficacy Bazedoxifene bazedoxifene acetate candidate cholesterol cholesterol distribution citrate clinical Clomifene Clomifene citrate contagious coronavirus Coronaviruses Critical delta variant distribution drugs Effect Efficacy endosome acidification Estrogen estrogen receptor evaluated exhibited expression hamster hamsters human cell lines humans identify in vitro in vivo infect Infection information inhibited inhibitor interleukin-6 offer omicron Omicron variant pathogenic variant penetration Postinfection pseudovirus pseudoviruses pulmonary viral reduced reveal SARS-CoV SARS-CoV-2 SARS-COV-2 infection selective selective estrogen receptor modulator severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Severe acute respiratory syndrome coronavirus 2. Tamoxifen toremifene toremifene citrate variant Vero E6 Vero E6 cell VERO E6 cells weight loss [DOI] 10.1002/jmv.27951 PMC 바로가기 [Article Type] Article
Genomic diversity of SARS-CoV-2 in Pakistan during the fourth wave of pandemic전염병의 네 번째 물결 동안 파키스탄에서 SARS-CoV-2의 게놈 다양성Article Published on 2022-10-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] A222V acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected Alpha B.1.617.2 Beta variant characteristic circulating circulation conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 D950N delta variant Delta variants exhibited followed by G142D genomic Genomic surveillance Germany globe highlight Illumina isolate isolates Karachi L452R lineages P681R Pakistan pandemic Patient Phylogenetic analysis SARS-CoV-2 SARS-CoV-2 strain severe acute respiratory syndrome Coronavirus Singapore spike mutation T19R T478K United Kingdom V483A variant variants variants of concern variants of concern. whole-genome sequencing [DOI] 10.1002/jmv.27957 PMC 바로가기 [Article Type] Article
Genomic surveillance of the Lambda SARS-CoV-2 variant in a global phylogenetic context글로벌 계통 발생학적 맥락에서 Lambda SARS-CoV-2 변이체의 게놈 감시Article Published on 2022-10-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis carried clade coronavirus country detect determine downloaded Endemic epidemiologically Europe genomic Genomic surveillance GISAID GISAID database identify isolate Lambda Lineage Local local outbreak local outbreaks local outbreaks.. North America occurred Pandemics past Phylogenetic Phylogenetic analysis Phylogenetic relationship prevalent SARS-CoV-2 SARS-CoV-2 variant sequence Sequencing severe acute respiratory syndrome Coronavirus South America spike spike mutation spike mutations Spread Surveillance variant variants of concern virus [DOI] 10.1002/jmv.27889 PMC 바로가기 [Article Type] Article
A systematic review and meta-analysis of the IgA seroprevalence in COVID-19 patients: Is there a role for IgA in COVID-19 diagnosis or severity?COVID-19 환자의 IgA 혈청 유병률에 대한 체계적인 검토 및 메타 분석: COVID-19 진단 또는 중증도에서 IgA의 역할이 있습니까?Meta-Analysis Published on 2022-10-012022-09-11 Journal: Microbiological research [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료기술, [키워드] Abstract acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody association asymptomatic patients Biomarker caused coronavirus coronavirus disease COVID-19 COVID-19 diagnosis COVID-19 disease determine diagnostic diagnostic test diagnostic tests disease Efficacy Health health problems Humoral response humoral responses IgA Immunity in some include Infection manuscript Meta-analysis Mild observé Patient problems produced Research respiratory SARS-CoV-2 SARS-CoV-2 PCR Seroprevalence severe acute respiratory syndrome Coronavirus Severe patient severe patients severity Susceptibility. symptomatic systematic review Vaccines [DOI] 10.1016/j.micres.2022.127105 PMC 바로가기 [Article Type] Meta-Analysis
Mechanisms of host type I interferon response modulation by the nucleocapsid proteins of alpha- and betacoronaviruses알파 및 베타 코로나바이러스의 뉴클레오캡시드 단백질에 의한 숙주 유형 I 인터페론 반응 조절 메커니즘Review Published on 2022-10-012022-09-11 Journal: Archives of Virology [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료법, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha animals Antiviral antiviral responses betacoronavirus cause coronavirus Coronavirus infections COVID-19 pandemic Critical diarrhea epidemic diarrhea facilitate Fatality rate function genomic RNA Health Host Human humans initial innate immune response involved knowledge modulate modulation Neonatal nucleocapsid protein Nucleocapsid proteins PEDV Replication responses responsible SARS-CoV-2 severe acute respiratory syndrome Coronavirus shown Signaling type I interferon viral genomic RNA Viral RNA virions virus Virus-host interactions [DOI] 10.1007/s00705-022-05513-8 PMC 바로가기 [Article Type] Review
Automated, portable, and high-throughput fluorescence analyzer (APHF-analyzer) and lateral flow strip based on CRISPR/Cas13a for sensitive and visual detection of SARS-CoV-2SARS-CoV-2의 감도 및 시각적 검출을 위한 CRISPR/Cas13a 기반의 자동화된 휴대용 고처리량 형광 분석기(APHF 분석기) 및 측면 흐름 스트립Article Published on 2022-10-012022-09-11 Journal: Talanta [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addressed amplification automated biosensor Care Contamination coronavirus COVID-19 CRISPR CRISPR/Cas13a detect Detection limit develop globe Health Lateral lateral flow strip MOST On-site detection ORF1ab gene POCT Point point of care Point of care testing (POCT) polymerase provided recombinase polymerase amplification Recombinase polymerase amplification (RPA) RPA S gene SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2. severe acute respiratory syndrome Coronavirus specificity Visualization [DOI] 10.1016/j.talanta.2022.123594 PMC 바로가기 [Article Type] Article
Engineering light-initiated afterglow lateral flow immunoassay for infectious disease diagnostics감염성 질병 진단을 위한 빛 개시 잔광 측방 유동 면역분석 엔지니어링Article Published on 2022-09-152022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptive addition Afterglow aggregation contagious disease contagious diseases coronavirus Detection sensitivity Diagnosis diagnostics Engineering Fluorescence fluorescent gold Gold nanoparticle HIV Human immunodeficiency virus immunodeficiency virus Infectious disease Lateral lateral flow immunoassay LFIA mechanism naked eye optical oxygen pandemic platform POCT point-of-care reporter SARS-CoV-2 SARS-CoV-2. sensitivity severe acute respiratory syndrome Coronavirus singlet oxygen substrate test strip [DOI] 10.1016/j.bios.2022.114411 PMC 바로가기 [Article Type] Article