androgens – Page 2 – Communicable Diseases Research

Do Anti-androgens Have Potential as Therapeutics for COVID-19?

항안드로겐이 COVID-19 치료제로 가능성이 있습니까?

Article

Published on 2021-08-012022-09-11
Journal: Endocrinology [Category] SARS, 유전자 메커니즘,

Androgenic hormones and the excess male mortality observed in COVID-19 patients: new convergent data

안드로겐 호르몬과 COVID-19 환자에서 관찰된 과잉 남성 사망률: 새로운 수렴 데이터

Article

Published on 2021-08-012022-09-11
Journal: World Journal of Urology [Category] SARS, 유전자 메커니즘,

[키워드] Abstract androgens COVID-19 excess excess mortality hormone male Mortality SARS-CoV-2 TMPRSS2
[DOI] 10.1007/s00345-020-03284-y PMC 바로가기 [Article Type] Article

An overview of sex hormones in relation to SARS-CoV-2 infection

Review

Published on 2021-07-202022-10-31
Journal: Future Virology [Category] COVID-19,

Severely low testosterone in males with COVID-19: A case-control study

COVID-19에 걸린 남성의 매우 낮은 테스토스테론: 사례 대조 연구

Article

Published on 2021-07-012022-09-11
Journal: Andrology [Category] 바이오마커,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus age androgen androgens association BMI case-control study CCI Charlson Comorbidity Index circulating clinical and laboratory parameters Clinical outcome clinical outcomes Cohort collected Comorbidities Comorbidity coronavirus COVID-19 death defined demographic Descriptive statistics greater healthy healthy control healthy controls higher risk Hospital admission hypogonadism ICU ICU admission IL-6 independent Infection intensive care intensive care unit Laboratory Laboratory parameters laboratory-confirmed Laboratory-confirmed COVID-19 linear logistic regression model Lower male material men multivariable multivariable logistic regression multivariable logistic regression models outcome Patient patients patients with COVID-19 respiratory risk SARS-CoV-2 SARS-COV-2 infection secondary hypogonadism serum severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Sex sex steroids significantly lower steroid Steroids symptomatic tested Testosterone transferred variable was used
[DOI] 10.1111/andr.12993 PMC 바로가기 [Article Type] Article

Androgen regulation of pulmonary AR, TMPRSS2 and ACE2 with implications for sex-discordant COVID-19 outcomes

성 불일치 COVID-19 결과에 대한 영향과 함께 폐 AR, TMPRSS2 및 ACE2의 안드로겐 조절

Article

Published on 2021-05-272022-09-10
Journal: Scientific Reports [Category] 유전자 메커니즘, 진단, 치료기술,

SARS-CoV-2 Viral Entry Proteins in Hyperandrogenemic Female Mice: Implications for Women with PCOS and COVID-19

안드로겐과다증 암컷 마우스의 SARS-CoV-2 바이러스 진입 단백질: PCOS 및 COVID-19가 있는 여성에게 미치는 영향

Article

Published on 2021-04-252022-09-12
Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 진단,

[키워드] ACE2 ACE2 mRNA ACE2 protein ADAM ADAM17 Affect androgen Androgen receptor androgens angiotensin angiotensin I angiotensin I converting enzyme 2 Body body composition body weight Brain cardiometabolic cathepsin cathepsin L causative agent cecum characterized Comorbidities COVID-19 COVID-19 pathology determined by Dihydrotestosterone disorder downregulated dysfunction elevated ELISA Endocrine enzyme fasting fasting glucose fat furin Glucose heart highlight host cell host cells host proteases hyperandrogenism infect kidney lean mass lung male mass mice morphology Mortality mRNA multiple tissue multiple tissues obesity organ systems ovarian Ovary ovulatory pathology Patient Polycystic polycystic ovary Polycystic ovary syndrome priming protease proteases Tmprss2 Protein protein level protein levels qPCR quantified receptor regulate renal risk risk factor Risk factors RT-qPCR SARS-CoV-2 SARS-CoV-2 entry serum severe COVID-19 severity small intestine tissues TMPRSS2 TMPRSS4 treated Treatment upregulated Urine was determined was measured Western-blot with COVID-19 women
[DOI] 10.3390/ijms22094472 PMC 바로가기 [Article Type] Article

Androgens, the kidney, and COVID-19: an opportunity for translational research

안드로겐, 신장, 그리고 코로나19: 중개 연구의 기회

Article

Published on 2021-02-012022-09-11
Journal: American journal of physiology. Renal physiology [Category] MERS, 유전자 메커니즘, 진단,

[키워드] ACE2 Acute kidney injury acute respiratory syndrome acute respiratory syndrome coronavirus affected affecting AKI alteration androgen androgens angiotensin Angiotensin-converting enzyme cardiometabolic cardiovascular diseases causative agent chronic kidney diseases coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 infection death rate diabetes Diabetes Mellitus discrepancy Diseases effective enzyme explain hypertension impair imperative implicated independent kidney Kidney diseases male Male sex men morbidity and mortality Mortality organ outcome pandemic Patient patients with COVID-19 Perspective preexisting comorbidities preexisting comorbidity proportions reached receptor renal renal diseases Renin renin-angiotensin system reported Research respiratory risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 severity Sex shown translational with COVID-19
[DOI] 10.1152/ajprenal.00601.2020 PMC 바로가기 [Article Type] Article

COVID-19 Infection in Men on Testosterone Replacement Therapy

Case Reports

Published on 2021-01-012023-07-06
Journal: The journal of sexual medicine [Category] SARS,

[키워드] androgens COVID-19 hypogonadism SARS-CoV-2 Testosterone Testosterone Replacement Therapy Venous Thromboembolism
[DOI] 10.1016/j.jsxm.2020.09.013 PMC 바로가기 [Article Type] Case Reports

Sex differences in COVID-19: the role of androgens in disease severity and progression

COVID-19의 성별 차이: 질병 중증도 및 진행에서 안드로겐의 역할

Review

Published on 2020-11-112022-09-10
Journal: Endocrine [Category] MERS, SARS, 변종,

[키워드] affected androgen Androgen receptor Androgen receptors androgens CAG repeats children clinical trial condition COVID-19 COVID-19 disease COVID-19 disease severity COVID-19 progression COVID-19 treatment Critical Dexamethasone disease disease severity drug Evidence evidence of explain facilitate fatality help Hospitalization Host Hydroxychloroquine implicated Infection men morbidity Mortality nitric oxide outcome outcomes pandemic pathophysiology Pathways Patient percentage prepubertal progression promoter Prostate cancer protease receptor Result SARS-CoV2 SARS-CoV2 infection sensitivity Sensitivity test sensitivity tests Serine serine 2 sex hormone Sex hormones Spike proteins suggested Testosterone therapy TMPRSS2 Transcription transmembrane protease serine 2 Treatment variants Viral viral infectivity virus spike protein women
[DOI] 10.1007/s12020-020-02536-6 PMC 바로가기 [Article Type] Review

The role of androgens in COVID-19

COVID-19에서 안드로겐의 역할

Review

Published on 2020-11-012022-09-11
Journal: Diabetes & metabolic syndrome [Category] 치료제,

[키워드] ACE-2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect allergy alopecia androgen androgenic alopecia androgens angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 article Asthma asthma medications cause causes Combination complications condition control group coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection effective Estrogen evaluate Evidence evidence of expressed expression Factors females functional Gender hair Hair loss health emergency higher risk hormone Hormones hospitalized patient hospitalized patients host cells hyperandrogenism immune system increased risk Infection lung tissue male male hormones medication multifactorial pandemic Patient patients with COVID-19 polycystic ovary Prevalence Prostate protease receptor Research respiratory Respiratory disease SARS-CoV-2 SARS-CoV-2 entry Serine serine 2 severe acute respiratory syndrome Coronavirus severe complication severe complications severe COVID-19 severity of symptom Sex hormones sexual suppresse susceptibility syndrome Testosterone TMPRSS2 transmembrane with COVID-19 women
[DOI] 10.1016/j.dsx.2020.10.014 PMC 바로가기 [Article Type] Review