anti-inflammatory property – Page 2 – Communicable Diseases Research

Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomics

COVID-19 햄스터 모델에서 덱사메타손 및 항체 치료의 주요 이점, 단일 세포 전사체로 밝혀짐

Article

Published on 2022-05-042022-09-11
Journal: Molecular therapy : the journal of the American So [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단, 치료법, 치료제,

The possible role of ursolic acid in Covid-19: A real game changer

Research article

Published on 2022-02-012022-10-05
Journal: Clinical nutrition ESPEN [Category] COVID19(2023년), SARS, 신약개발, 임상, 치료제,

An in silico analysis identifies drugs potentially modulating the cytokine storm triggered by SARS-CoV-2 infection

실리코 분석은 SARS-CoV-2 감염에 의해 유발된 사이토카인 폭풍을 잠재적으로 조절하는 약물을 식별합니다

Article

Published on 2022-01-312022-09-10
Journal: Scientific Reports [Category] 신약개발, 유전자 메커니즘, 치료제,

[키워드] “cytokine storm” addition Analysis anti-inflammatory properties anti-inflammatory property approach BALF Bronchoalveolar lavage fluid cause causes Computational biology and bioinformatics connectivity COVID-19 COVID-19 mortality COVID-19 pandemic COVID-19 patient Cytokines Data mining dataset drug Effect expected female hormone glucocorticoid Glucocorticoids Health help human cell lines identify immune response immune responses in silico analysis in vitro data Inflammatory Map MEK inhibitor modulating molecules Mortality negative regulation pathology pathway Pathways PKC predicted reveal SARS-CoV-2 SARS-COV-2 infection small molecule Small molecules supported the cytokine storm these compounds Transcription Transcriptome transcriptomic data Treatment triggered
[DOI] 10.1038/s41598-022-05597-x PMC 바로가기 [Article Type] Article

Protective Role of Combined Polyphenols and Micronutrients against Influenza A Virus and SARS-CoV-2 Infection In Vitro

Article

Published on 2021-11-192022-10-28
Journal: Biomedicines [Category] COVID-19,

[키워드] acute respiratory syndrome analyzed anti-inflammatory property antiviral activity Antiviral effect antiviral efficacy antivirals Combined coronavirus COVID-19 cytokine production demonstrated Efficacy evaluated expression IL-6 Infection Influenza Influenza virus inhibit inhibiting inhibitory effect mechanism Micronutrient micronutrients Polydatin polyphenol polyphenols post infection precursor reduced Replication replicative respiratory virus Respiratory virus infections resveratrol role SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections significantly tested Treatment Vero E6 cell Viral protein virus virus-infected cells
[DOI] 10.3390/biomedicines9111721 PMC 바로가기 [Article Type] Article

Curcumin Inhibits In Vitro SARS-CoV-2 Infection In Vero E6 Cells through Multiple Antiviral Mechanisms

Curcumin은 다중 항바이러스 메커니즘을 통해 Vero E6 세포의 시험관 내 SARS-CoV-2 감염을 억제합니다

Article

Published on 2021-11-162022-09-10
Journal: Molecules [Category] MERS, SARS, 변종, 유전자 메커니즘, 치료제,

[키워드] addition Affect anti-inflammatory effect anti-inflammatory property Antiviral antiviral activity Antiviral effect COVID-19 Curcumin Cytokines cytotoxicity D614G D614G strain delta variant ELISA evaluated exhibit exhibited IL-1β IL-6 IL-8 immune response in vitro independent Infection Inflammation inhibited investigated mononuclear cell mononuclear cells MTT Multiple PBMC PBMCs Peripheral blood Peripheral blood mononuclear cells Plaque assay Post-infection pro-inflammatory cytokine pro-inflammatory cytokines qPCR quantified released replicative required SARS-CoV-2 SARS-COV-2 infection scarcity the SARS-CoV-2 Therapeutic approach therapeutic approaches to define Treatment treatment strategy triggered Vero E6 VERO E6 cells Viral viral titer virucidal were used
[DOI] 10.3390/molecules26226900 PMC 바로가기 [Article Type] Article

Diosmectite inhibits the interaction between SARS-CoV-2 and human enterocytes by trapping viral particles, thereby preventing NF-kappaB activation and CXCL10 secretion

Article

Published on 2021-11-052022-10-29
Journal: Scientific Reports [Category] COVID-19, SARS,

[키워드] ACE2 ACE2 receptor Activation analyzed angiotensin-converting enzyme 2 anti-inflammatory property binding Caco-2 Caco-2 cell Cell cells component COVID-19 management protocols CXCL10 diarrhea Diosmectite domain downstream Effect Effects ELISA Enterocyte Evidence gastroenterology Gastrointestinal models gastrointestinal system heat-inactivated immunofluorescence Inflammation inhibit inhibited Interaction intestine limit management membranes nuclear Pathogenesis pathogenic patients Prevent public health RBD receptor SARS-CoV-2 secretion Spike protein Symptom tested the spike protein Trapping Treatment Viral particles viral spread virus
[DOI] 10.1038/s41598-021-01217-2 PMC 바로가기 [Article Type] Article

Redressing the interactions between stem cells and immune system in tissue regeneration

Review

Published on 2021-10-202022-10-28
Journal: Biology Direct [Category] COVID-19, Fulltext, MERS,

[키워드] Activation addition AhR Anti-inflammatory anti-inflammatory property Aryl hydrocarbon receptor Characteristics Course COVID-19 degenerative Effect effective expression facilitate functions growth factor IDO IFN-γ IGF2 Immune cell immune cells immune system immunomodulation immunomodulatory Indoleamine 2,3-dioxygenase Inflammation inflammatory disorder insulin Interaction interferon-γ Kynurenic acid Macrophage metabolites molecular Muscle repair muscle stem cell MuSCs oxidative phosphorylation pathological conditions produced regenerative stem cell therapeutic effect tissue regeneration tissue repair TNF-α tumor necrosis factor-α turn
[DOI] 10.1186/s13062-021-00306-6 PMC 바로가기 [Article Type] Review

WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2

Cell Biology

Published on 2021-10-082022-10-28
Journal: PeerJ [Category] COVID-19,

[키워드] “cytokine storm” acute respiratory syndrome Angiotensin-converting enzyme Anti-inflammatory anti-inflammatory property cannabinoid cannabinoids caused complementary coronavirus Coronavirus disease 2019 COVID-19 COVID-19 patients Effect eight hallmark heart tissue high risk Human iPSC-derived cardiomyocytes infect infected cells infected with SARS-CoV-2 Inflammation Inflammatory Injury investigated lactate dehydrogenase LDH manifestation modify modulating Mortality myocardial injury organs pro-inflammatory cytokines protein levels reduced reducing released Replication SARS-CoV-2 SARS-COV-2 infection severe COVID-19 survival therapeutic TNF-α triggered tumor necrosis factor-alpha viral infection WIN 55,212-2
[DOI] 10.7717/peerj.12262 PMC 바로가기 [Article Type] Cell Biology

Low-dose radiation therapy (LDRT) for COVID-19 and its deadlier variants

COVID-19 및 그 치명적인 변종에 대한 저선량 방사선 요법(LDRT)

Article

Published on 2021-10-012022-09-11
Journal: Archives of Toxicology [Category] 변종,

Catechins: Therapeutic Perspectives in COVID-19-Associated Acute Kidney Injury

카테킨: COVID-19 관련 급성 신장 손상의 치료적 관점

Review

Published on 2021-09-302022-09-10
Journal: Molecules [Category] SARS, 치료제,

[키워드] activities activity Acute kidney injury AKI anti-inflammatory properties anti-inflammatory property anti-SARS-CoV-2 antioxidant association Cardiovascular disorders catechin characterized Comorbidities coronavirus COVID-19 patient COVID-19 patients Critically ill critically ill COVID-19 patients decrease develop disorder Effect epigallocatechin-3-gallate (EGCG) etiology Evidence evidence of Factors flavonoids green tea Hospital stay impairment In-hospital death intensive care unit Kidney injury medicinal plant Mortality natural products nephrotoxic nephrotoxicity obstructive nephropathy Organ failure organ failures Patient Perspective pharmacological provided renal renal disease renal disorder renal function renal replacement therapy reno-protective effect replacement therapy RRT SARS-CoV-2 shown sustained Therapeutics those with comorbidity
[DOI] 10.3390/molecules26195951 PMC 바로가기 [Article Type] Review