Development of a genetic tool for functional screening of anti-malarial bioactive extracts in metagenomic libraries항말라리아 생리활성 추출물의 기능적 스크리닝을 위한 유전적 도구 개발 메타유전체 라이브러리에서Methodology Published on 2015-06-042024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Anti-malarial drugs Bioluminescent Plasmodium falciparum Dermaseptin 4 Functional screening malaria metagenomics Synthetic gene design [DOI] 10.1186/s12936-015-0748-6 PMC 바로가기 [Article Type] Methodology
Drugs use pattern for uncomplicated malaria in medicine retail outlets in Enugu urban, southeast Nigeria: implications for malaria treatment policy엔우구 도시, 나이지리아 동남부의 약국에서 단순 말라리아에 대한 약물 사용 패턴: 말라리아 치료 정책에 대한 시사점Research Published on 2014-06-242024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Affordable Medicines Facility-malaria Anti-malarial drugs Artemisinin-based combination therapy Private retail sector Utilization pattern [DOI] 10.1186/1475-2875-13-243 PMC 바로가기 [Article Type] Research
Repositioning: the fast track to new anti-malarial medicines?재배치: 새로운 항말라리아 약물로 가는 빠른 길?Research Published on 2014-04-142024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Anti-malarial drugs Candidate drug re-profiling drug repositioning in vitro in vivo malaria Plasmodium berghei Plasmodium falciparum [DOI] 10.1186/1475-2875-13-143 PMC 바로가기 [Article Type] Research
Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen FamiliesPlasmodium falciparum의 유사분열 진화는 안정적인 핵심 게놈을 보여주지만 항원 가족에서 재조합을 보여줍니다Research Article Published on 2013-02-072022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 말라리아, [키워드] absence allele amplification Analysis anti-malarial drug Anti-malarial drugs antigenic variation atovaquone Author average base pair change chromosomal crossover chromosomal crossovers chromosome chromosome 1 clone clones Combination Complete core core genome cytochrome b death Deletion determined develop different disease drug drug pressure drug resistance drug target effort evade event Evolution family FIVE found Frequency Gene gene families genetic change Genetic changes Genome genomic alteration global health Haplotype Health help Host Host immune response host immune responses human host immune evasion immune resistance immune response immune responses IMPROVE in vitro increase individual level Infectious disease initiated involved malaria malaria parasites microarray technique mitosis mitotic mitotic recombination mrp1 Multidrug resistance multigene families multigene family Mutation mutation rate Mutation rates natural infection nucleotide occur P. falciparum parasite parasites Plasmodium Plasmodium falciparum plasticity populations presence or absence Protein Recombination recombination event Region responsible sequence variability show Single nucleotide variant single nucleotide variants STABLE strain Structural variant structural variants subtelomeric region subtelomeric regions var gene family whole-genome microarray whole-genome sequencing [DOI] 10.1371/journal.pgen.1003293 PMC 바로가기 [Article Type] Research Article
Sustainable malaria control: transdisciplinary approaches for translational applications지속 가능한 말라리아 통제: 변환 응용을 위한 초학제적 접근법Review Published on 2012-12-262024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Anopheles Anti-malarial drugs DDT Plasmodium vector control [DOI] 10.1186/1475-2875-11-431 PMC 바로가기 [Article Type] Review
Optimizing the HRP-2 in vitro malaria drug susceptibility assay using a reference clone to improve comparisons of Plasmodium falciparum field isolatesHRP-2를 최적화하여 말라리아 약물 감수성 시험을 수행하고, 참조 클론을 사용하여 플라스모디움 팔시파룸 현장 분리체의 비교를 개선합니다.Research Published on 2012-09-132024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Anti-malarial drugs drug resistance Drug susceptibility test ELISA HRP-2 malaria Plasmodium falciparum [DOI] 10.1186/1475-2875-11-325 PMC 바로가기 [Article Type] Research
Drug treatment of malaria infections can reduce levels of protection transferred to offspring via maternal immunity말라리아 감염에 대한 약물 치료는 모성 면역을 통해 자손에게 전달되는 보호 수준을 감소시킬 수 있다.Article Published on 2012-06-222024-08-14 Journal: Proceedings of the Royal Society B: Biological Sciences [Category] 말라리아, [키워드] Anti-malarial drugs immunoglobulins Maternal effects neonatal immunology passive immunity Plasmodium chabaudi [DOI] 10.1098/rspb.2011.1563 PMC 바로가기
Ex vivo drug sensitivity profiles of Plasmodium falciparum field isolates from Cambodia and Thailand, 2005 to 2010, determined by a histidine-rich protein-2 assay캄보디아와 태국의 2005년부터 2010년까지의 플라스모디움 팔시파룸 현장 분리주에 대한 ex vivo 약물 감수성 프로파일, 히스티딘 풍부 단백질-2 분석에 의해 결정됨Research Published on 2012-06-132024-08-14 Journal: Malaria Journal [Category] 말라리아, [키워드] Anti-malarial drugs Cambodia drug resistance HRP-2 malaria Plasmodium falciparum [DOI] 10.1186/1475-2875-11-198 PMC 바로가기 [Article Type] Research
Relationship between treatment-seeking behaviour and artemisinin drug quality in Ghana치료 추구 행동과 가나의 아르테미시닌 약물 품질 간의 관계Research Published on 2012-04-062024-08-14 Journal: Malaria Journal [Category] 말라리아, [키워드] Anti-malarial drugs Artemisinin Counterfeit drug quality Ghana [DOI] 10.1186/1475-2875-11-110 PMC 바로가기 [Article Type] Research