Apolipoprotein e – Page 2 – Communicable Diseases Research

Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system

Research Article

Published on 2020-05-252022-11-01
Journal: Glia [Category] Coronavirus, MERS,

[키워드] Activation addition Apolipoprotein e CD4+ T cell CD45+ CD86 Cell Central nervous system CNS colony stimulating factor coronavirus Coronavirus infection Coronavirus replication correlated CSF1R cystatin damaged decreased expression Defense demonstrated Demyelination dendritic cells deplete Depletion disease elevated ENhance expressed expression functional growth factor Host host defense impair implicated increase increase in increased mortality Infection inhibitor Macrophage macrophages MHC class mice microenvironment microglia mouse hepatitis virus murine myeloid cell nerve tissue neurologic neurotropic osteopontin PLX5622 Population Protein receptor remyelination RNA sequencing severity susceptible T cell transcript Treatment viral replication
[DOI] 10.1002/glia.23844 PMC 바로가기 [Article Type] Research Article

Impact of apolipoprotein E genetic polymorphisms on liver disease: An essential review

Review

Published on 2020-01-012023-06-13
Journal: Annals of hepatology [Category] B형 간염,

[키워드] Apolipoprotein e Liver cirrhosis liver diseases Liver transplantation Polymorphisms
[DOI] 10.1016/j.aohep.2019.07.011 [Article Type] Review

Age, Gender, and Cancer but Not Neurodegenerative and Cardiovascular Diseases Strongly Modulate Systemic Effect of the Apolipoprotein E4 Allele on Lifespan

연령, 성별 및 암은 아니지만 신경퇴행성 및 심혈관 질환은 수명에 대한 아포지단백 E4 대립유전자의 전신 효과를 강력하게 조절합니다

Research Article

Published on 2014-01-302022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] adverse effect age allele Analysis ApoE APOE gene ApoE4 allele ApoE4 carrier APOE4 carriers Apolipoprotein Apolipoprotein e association Author Cancer cardiovascular cardiovascular and neurodegenerative diseases cardiovascular disease carriers Cohort cohorts compared CVD death deaths disease Diseases e4 allele e4 allele carrier e4 allele carriers e4 carrier e4 carriers Effect Enduring ENhance explain extreme family Family Study genetic origin genetic origins genotyped ApoE polymorphism Geriatrics Gerontology healthy heart Human human disease human diseases increase interfere large sample lead life Life expectancy lifespan Long Longitudinal studies Major mechanism mechanisms men moderate Mortality neurodegenerative neurodegenerative disorder neurodegenerative disorders Non-skin cancer offspring old ages participant polymorphism Population populations Relative risk resulting risk risk of death sensitivity skin cancer survival systemic women
[DOI] 10.1371/journal.pgen.1004141 PMC 바로가기 [Article Type] Research Article