Germline rare variants of lectin pathway genes predispose to asymptomatic SARS-CoV-2 infection in elderly individuals렉틴 경로 유전자의 생식선 희귀 변이체는 노인에서 무증상 SARS-CoV-2 감염을 일으키기 쉽습니다.Article Published on 2022-08-012022-09-11 Journal: Genetics in medicine : official journal of the Ame [Category] COVID19(2023년), SARS, 변종, [키워드] allelic variant allelic variants Asymptomatic Asymptomatic COVID-19 asymptomatic individual Asymptomatic individuals asymptomatic subject Cohort COLEC10 COLEC11 Collapsing complement complement system COVID-19 decreased activity decreased expression enrichment ES European Evidence exome sequencing data Genes Genetic genetic data Genome Aggregation Database germline Hospitalized hospitalized patient Hyperactivation individual individuals investigated lectin lectin pathway lung tissue MASP1 outcome performed phenotype predicted PROTECT prothrombin rare variant replicated SARS-CoV-2 SARS-COV-2 infection serum severe COVID-19 severe disease susceptible variant with COVID-19 [DOI] 10.1016/j.gim.2022.04.007 PMC 바로가기 [Article Type] Article
Detection of SARS-CoV-2 in exhaled air using non-invasive embedded strips in masks마스크에 비침습적 내장 스트립을 사용하여 호기에서 SARS-CoV-2 감지Article Published on 2022-08-012022-09-11 Journal: American journal of infection control [Category] SARS, 치료기술, [키워드] alcohol approach asymptomatic individual Asymptomatic individuals comparable conditions COVID-19 detect detection Detection limit face Face masks feasibility Frequently Health individual individuals infected individuals Infection Infectious virus invasive Mask Masks nasal swab Non-invasive not correlated pandemic Personal protective equipment platform polyvinyl alcohol Protective qRT-PCR qRT-PCR analysis Quantitative RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 RNA secretion symptom status symptomatic individual tested Viral load viral loads Viral RNA virus vRNA Xerostomia [DOI] 10.1016/j.ajic.2022.01.010 PMC 바로가기 [Article Type] Article
Limitations of Molecular and Antigen Test Performance for SARS-CoV-2 in Symptomatic and Asymptomatic COVID-19 Contacts증상 및 무증상 COVID-19 접촉자에서 SARS-CoV-2에 대한 분자 및 항원 테스트 성능의 한계Article Published on 2022-07-202022-09-12 Journal: Journal of Clinical Microbiology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome Antigen antigen test Asymptomatic individuals Cell culture close contact Contact coronavirus COVID-19 Culture diagnostics enrolled identify in viral individual Infection limitation Molecular assay nasopharyngeal NAT nucleic acid test pandemic participant performance performed PerkinElmer platform positive positive sample Probability rapid diagnostics recruited reference Repeat reverse transcription-PCR RT-PCR RT-PCR assay Saliva SARS-CoV-2 SARS-CoV-2 testing SARS-CoV-2-positive individual Swab Symptom symptomatic Test test performance tested Transport media VTM [DOI] 10.1128/jcm.00187-22 PMC 바로가기 [Article Type] Article
Viral RNA Load and Infectivity of SARS-CoV-2 in Paired Respiratory and Oral Specimens from Symptomatic, Asymptomatic, or Postsymptomatic Individuals무증상, 무증상 또는 무증상 개인의 호흡기 및 구강 표본에서 SARS-CoV-2의 바이러스 RNA 부하 및 감염성Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 치료기술, [키워드] anterior nares Asymptomatic Asymptomatic individuals asymptomatic patient asymptomatic patients bodily secretions Care care provider classic close contact collected COVID-19 COVID-19 diagnosis Critical diagnosed with COVID-19 diagnostic diagnostic sensitivity diagnostic testing epidemiological FIVE followed by Frequency Health Health care help individual individuals infection with SARS-CoV-2 Infectious virus Infectivity information initial Isolation load molecular nare nares nasopharyngeal oral patients platform positive individual positive individuals provide quarantine respiratory RNA RT-PCR Saliva saliva specimens Sample Sampling frequency SARS-CoV-2 secretion sensitivity specimen specimens Surveillance Swab swabs symptomatic symptomatic patient Symptomatic patients tested The diagnostic sensitivity understanding viral RNA load virus detection virus infectivity virus isolation was determined [DOI] 10.1128/spectrum.02264-21 PMC 바로가기 [Article Type] Article
Thoracic imaging tests for the diagnosis of COVID‐19Article Published on 2022-06-162022-10-06 Journal: Cochrane database of systematic reviews [Category] COVID19(2023년), SARS, 진단, [키워드] 95% CI 95% confidence interval Accuracy age applicability articles Asymptomatic Asymptomatic individuals cause CDC Chest Chest CT Clinical sign Combination comparison Computed tomography concern COVID‐19 criteria CT findings Definition diagnosing Diagnosis diagnostic Effect eight estimate estimates evaluate evaluated Evidence example excluded Final heterogeneity imaging imaging test indicated individual initial library limit lung MOST participant Participants Pneumonia polymerase chain positive ranged recruited reference reference standard Repository Respiratory illness resulting risk of bia RT‐PCR SARS‐CoV‐2 infection screened searched sensitivity Sensitivity and specificity Seven specificity Stephen Symptoms Thoracic threshold transcriptase University of Bern utility [DOI] 10.1002/14651858.CD013639.pub5 [Article Type] Article
Serum microRNAs targeting ACE2 and RAB14 genes distinguish asymptomatic from critical COVID-19 patientsResearch article Published on 2022-06-112022-10-05 Journal: Molecular Therapy. Nucleic Acids [Category] 바이오마커, 변종, 진단, [키워드] ACE2 analyzed approach Asymptomatic asymptomatic individual Asymptomatic individuals Biomarkers candidate change Control controls COVID-19 COVID-19 disease COVID-19 progression Critical critical COVID-19 patient determine disease disease severity expression Factor future therapeutic Host identify in silico analysis in viral individual Inflammatory response mechanism microRNA miRNA MT: Non-coding RNAs pathology Patient performed Potential biomarker promote Protein question RAB14 Replication respond SARS-CoV-2 serum target gene TMPRSS2 upregulated viral entry viral infection were measured [DOI] 10.1016/j.omtn.2022.06.006 [Article Type] Research article
Seroprevalence of Anti-S1-RBD Antibodies in Pre-pandemic and Pandemic Subjects From Hail Region, KSA우박 지역, KSA의 전염병 전 및 전염병 대상체에서 항-S1-RBD 항체의 혈청유병률Article Published on 2022-06-092022-09-11 Journal: Frontiers in Public Health [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] age antibodies antibody level antibody levels Antigen asymptomatic individual Asymptomatic individuals Care clinical and demographic factors clinically collected complications Containment COVID-19 Demographic factors develop Efficacy effort ELISA exhibited exposure to female females group Hail house humoral immune responses identification immune responses in-house ELISA Infection male management neutralizing antibody new SARS-CoV-2 other coronavirus other coronaviruses pandemic positive Protein RBD antigen reduced Region required Research S-RBD S1-RBD Sample SARS-CoV-2 Screen Seroprevalence serum serum antibodies serum antibody serum IgG antibodies serum IgG antibody significantly significantly higher subject Surveillance the SARS-CoV-2 Vaccine variant variants [DOI] 10.3389/fpubh.2022.874741 PMC 바로가기 [Article Type] Article
Diagnostic accuracy of non-invasive detection of SARS-CoV-2 infection by canine olfaction개의 후각에 의한 SARS-CoV-2 감염의 비침습적 검출 진단 정확도Article Published on 2022-06-012022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI Accuracy Antigen antigenic approach Asymptomatic asymptomatic individual Asymptomatic individuals canine cohort study collected Community COVID-19 COVID-19 pandemic diagnostic Diagnostic accuracy indication individual Mass screening nasopharyngeal Nasopharyngeal swab Non-invasive NPs olfactory participant positive Prospective prospective cohort study reached reference standard RT-PCR Saliva SARS-COV-2 infection sensitivity specificity Sweat symptomatic tested were blinded [DOI] 10.1371/journal.pone.0268382 PMC 바로가기 [Article Type] Article
ESCMID COVID-19 guidelines: diagnostic testing for SARS-CoV-2ESCMID COVID-19 가이드라인: SARS-CoV-2에 대한 진단 테스트Article Published on 2022-06-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] adaptation age antigen detection approach assessment Asymptomatic individuals Care chair Clinicians close contact Committee COVID-19 COVID-19 guideline de novo development Diagnosis diagnostic diagnostic test disease severity Evidence exposure to Guidance guidelines Health Health care healthcare Healthcare workers identify individual infected with SARS-CoV-2 Intervention involved list majority nucleic acid nucleic acid amplification once a week outcome Patient performed PICO Quality question recommendation recommendations risk SARS-CoV-2 selected severe disease Signs and symptoms Symptom systematic reviews Task Force Testing was used [DOI] 10.1016/j.cmi.2022.02.011 PMC 바로가기 [Article Type] Article
RT-qPCR-based tests for SARS-CoV-2 detection in pooled saliva samples for massive population screening to monitor epidemics전염병 모니터링을 위한 대규모 인구 스크리닝을 위한 혼합 타액 샘플에서 SARS-CoV-2 검출을 위한 RT-qPCR 기반 테스트Article Published on 2022-05-162022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] approach Asymptomatic individuals clinical sample clinical samples costly Ct values detect diagnostic diagnostic test diagnostics Epidemics False negative False positive FIVE gold gold standard infected individuals isolated RNA IVD MONITOR PCR testing pooling Population screening populations positive Probability Prophylactic qPCR test reached RNA RT-PCR testing RT-qPCR RT-qPCR test Saliva saliva samples SARS-CoV-2 detection SARS-CoV-2 infections screening test sensitivity side specificity subsequent Swab SYBR Green Testing throughput viral genome within 6 months [DOI] 10.1038/s41598-022-12179-4 PMC 바로가기 [Article Type] Article