build – Page 2 – Communicable Diseases Research

Biosynthetic proteins targeting the SARS-CoV-2 spike as anti-virals

Article

Published on 2022-09-062022-11-15
Journal: PLoS Pathogens [Category] SARS, 변종, 치료제,

Building Emotional Awareness and Mental Health (BEAM): study protocol for a phase III randomized controlled trial of the BEAM app-based program for mothers of children 18-36 months

Article

Published on 2022-09-052022-10-05
Journal: Trials [Category] 임상,

[키워드] Anxiety anxiety symptoms assessment Awareness build building children Cohort COVID-19 pandemic Depression Efficacy elevated emotion evaluate finding Follow-up Health IMPROVE improvement individual Intervention Maternal mental health mental health disorders mental illness mother occur pandemic Parenting pregnant Prevalence Primary outcome programming Psychoeducation Randomized Randomized controlled trial RCT RCT. recruited reducing repeated measure risk Secondary outcomes Stress Study protocol Support Symptom Symptoms symptoms of depression Tau treatment as usual treatment group Trial Two-arm used to evaluate
[DOI] 10.1186/s13063-022-06512-5 PMC 바로가기 [Article Type] Article

[Building COVID-19’s semiology: The blind wise men and the elephant]

Article

Published on 2022-09-012022-11-16
Journal: Gaceta sanitaria [Category] COVID19(2023년), SARS, 치료기술,

An agent-based model to assess large-scale COVID-19 vaccination campaigns for the Italian territory: The case study of Lombardy region

이탈리아 영토에 대한 대규모 COVID-19 예방 접종 캠페인을 평가하기 위한 에이전트 기반 모델: 롬바르디아 지역 사례 연구

Article

Published on 2022-09-012022-09-11
Journal: Computer methods and programs in biomedicine [Category] 변종,

[키워드] administration age agency agent agent-based model analyzed approach assigned available dose available doses build calibrated case study concern Covasim COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines cumulative current death deaths Definition dose dynamic early stages Effectiveness Epidemiologic model Free greater group Health Health care Health care worker health care workers help individual individuals Infection infections Italian Italy knowledge lombardy mathematical methodological methodology National nuances parameter priority reduction in Support the vaccine vaccination Vaccine Vaccines variant variants variants of concern
[DOI] 10.1016/j.cmpb.2022.107029 PMC 바로가기 [Article Type] Article

Understanding the epigenetic mechanisms in SARS CoV-2 infection and potential therapeutic approaches

SARS CoV-2 감염의 후성유전학적 기전과 잠재적인 치료적 접근의 이해

Review

Published on 2022-09-012022-09-11
Journal: Virus research [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Anti-viral immune response association build caused Community coronavirus COVID-19 disease severity DNA DNA methylation drug effective eliminating Epigenetic epigenetic regulator epigenetics Escalation Health highlight histone Histone modification host cell host cells immune immune responses Immunity Infection initial Interaction mechanism microRNA Modification Mortality pandemic Pathogenesis pathogenesis of SARS-CoV-2 reduced risk SARS CoV-2 SARS- CoV-2 SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity subsequent the disease Therapeutic approach therapeutic intervention Therapies understanding variants of SARS-CoV-2 viral infection Virology
[DOI] 10.1016/j.virusres.2022.198853 PMC 바로가기 [Article Type] Review

Increased burden of booster shots for COVID-19 amidst vaccine hesitancy in Pakistan

Short communication

Published on 2022-09-012022-10-05
Journal: Annals of Medicine and Surgery [Category] 변종,

[키워드] B.1.1.529 BNT162b2 vaccine booster build Care communication confirmed case counseling COVID-19 death effort expected immunized Increased likelihood mutate Mutation Novel coronavirus omicron pandemic provide reduce reported significantly the disease two-dose regimen vaccination Vaccine Vaccine hesitancy variant virus WHO World Health Organization
[DOI] 10.1016/j.amsu.2022.104360 [Article Type] Short communication

The disturbance of urban mobility in the context of COVID-19 pandemic

Short communication

Published on 2022-09-012022-10-05
Journal: Cities [Category] 변종, 치료기술,

[키워드] approach build change changes in COVID-19 COVID-19 cases COVID-19 effects COVID-19 pandemic Decline Epidemics Europe Frequency indicated Intercity mobility International mobility Kernel-based method New New York outbreak Outbreaks outlier outliers pandemic raised resulting SCR Time series pattern detection timelines Travel variations
[DOI] 10.1016/j.cities.2022.103821 [Article Type] Short communication

Low quantity and quality of anti-spike humoral response is linked to CD4 T-cell apoptosis in COVID-19 patients

Article

Published on 2022-08-272022-10-05
Journal: Cell Death & Disease [Category] SARS, 임상, 진단, 치료기술, 치료법,

[키워드] acute phase addition analyzed anti-S Anti-spike antibody-dependent cellular cytotoxicity Apoptosis apoptotic build CD4 T cell CD4 T-cell Cell contribute Convalescent patients coronavirus 2 correlated COVID-19 COVID-19 patient CXCL10 death demonstrated disease severity early phase help humoral IgA IgG IgG response IgM Immunoglobulin individual infected individual infected individuals Infection inflammatory reaction lymphopenia magnitude marker membrane neutralization pathogenicity Patient plasma predominant programmed cell death Proteins reducing reported respiratory response responses SARS-CoV-2 nucleocapsid soluble Fas ligand specific IgG antibodies T-cell the S protein
[DOI] 10.1038/s41419-022-05190-0 [Article Type] Article

Reliability of predictive models to support early decision making in the emergency department for patients with confirmed diagnosis of COVID-19: the Pescara Covid Hospital score

COVID-19 진단이 확인된 환자의 응급실에서 조기 의사 결정을 지원하는 예측 모델의 신뢰성: Pescara Covid Hospital 점수

Article

Published on 2022-08-192022-09-11
Journal: BMC health services research [Category] 변종,

[키워드] Abruzzo Accuracy Admission age and gender Algorithm Alpha build calibrated can be used carried Characteristics clinical decision collecting data conditions COVID-19 D-dimer death decision Decision making diabete diabetes diagnosed with COVID-19 Diagnosis disease distribution emergency department heterogeneous higher risk hospital hospital management hospitalisation identify independent predictor independent predictors initial intensive care Italy laboratory parameter Laboratory parameters Lactate lactate dehydrogenase Logistic regression monocyte other variant other variants outcome oxygen oxygen support pandemic parameter Patient patients with COVID-19 prediction Prediction score Predictive model predictive models predictor procalcitonin Prognosis renal renal disease Retrospective study risk Risk scores risk stratification saturation significantly Support survival threshold validation variants of concern virus were used
[DOI] 10.1186/s12913-022-08421-4 PMC 바로가기 [Article Type] Article

Withania somnifera (L.) Dunal (Ashwagandha) for the possible therapeutics and clinical management of SARS-CoV-2 infection: Plant-based drug discovery and targeted therapy

Article

Published on 2022-08-152022-11-15
Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 치료제,

[키워드] ACE2 ACE2 receptors acute respiratory syndrome Analysis Anti-viral antiviral activity article Ashwagandha build Clinical management Compound coronavirus Coronavirus disease 2019 COVID-19 Critical disease drug Drug discovery flu help Immune homeostasis implicated Infection Inflammation information inhibit knowledge management MPro multiple organs organs other compounds pandemic parameter Patient patients Population pro-inflammatory cytokine protease provided Regulation SARS-CoV-2 SARS-COV-2 infection secure Side effect Standardization targeted therapy the patient Treatment Vaccine virus was performed Withania somnifera
[DOI] 10.3389/fcimb.2022.933824 PMC 바로가기