Infectious Aerosol Capture Mask as Environmental Control to Reduce Spread of Respiratory Viral Particles호흡기 바이러스 입자의 확산을 줄이기 위한 환경 제어로서의 감염성 에어로졸 캡처 마스크Article Published on 2022-06-112022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 치료기술, [키워드] activities aerosol aerosol capture airborne isolation. alternative alternatives breath breathing can be used capture CFD collected Computational fluid dynamics Control coughing COVID-19 patient COVID-19 patients Critical described escaped evaluated experiment Filter indicated infected individual infected individuals Isolation Isolation room Laboratory Mask negative Negative pressure nosocomial Nosocomial transmission Particle Particles Patient respiratory RNA RNA copies SARS-CoV-2 Simulation speaking the patient These data Transmission undetectable virus concentration [DOI] 10.3390/v14061275 PMC 바로가기 [Article Type] Article
Egg-Derived Anti-SARS-CoV-2 Immunoglobulin Y (IgY) With Broad Variant Activity as Intranasal Prophylaxis Against COVID-19COVID-19에 대한 비강내 예방으로서 광범위한 변이 활성을 갖는 계란 유래 항-SARS-CoV-2 면역글로불린 Y(IgY)Clinical Trial Published on 2022-06-012022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, [키워드] 2019 novel coronavirus 2019-nCoV activity Administered Against Alpha anti-SARS-CoV-2 Antiviral approval approvals B.1.1.529 B.1.1.7 B.1.351 B.1.617.2 Beta binding capture chicken immunoglobulin clinical clinical trial clinical trial body Clinical use contagiousness Convalescent patients COVID-19 cross-reactivity Delta demonstrated develop Diseases distribution double-blind effective Emergency use authorization enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay Evidence evidence of greater healthy human tissue human tissues IgY Immunity immunized Immunoglobulin immunoglobulin Y index Infectious diseases intranasal intranasally multiple dose multiple doses nasal drop nasal drops nasal mucosa neutralization titer no evidence of Novel coronavirus omicron Phase 1 phase 1 study Placebo placebo-controlled Prevalence Prophylaxis raised Randomized RATs RBD Receptor-binding domain reduce reduced risk Safe safety profile SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 strain SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 viral sensitivity sera Spike protein the receptor-binding domain the SARS-CoV-2 Tolerability Transmission Trial Vaccine Vaccine hesitancy variants variants of concern variety Viral virus [DOI] 10.3389/fimmu.2022.899617 PMC 바로가기 [Article Type] Clinical Trial
Development of flow cytometry-based assays to assess the ability of antibodies to bind to SARS-CoV-2-infected and spike-transfected cells and mediate NK cell degranulationSARS-CoV-2 감염 및 스파이크 형질감염 세포에 결합하고 NK 세포 탈과립을 매개하는 항체의 능력을 평가하기 위한 유세포 분석 기반 분석법 개발Article Published on 2022-06-012022-09-11 Journal: Cytometry. Part A : the journal of the Internation [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제, [키워드] antibody Antibody binding Antibody Response Antibody responses Antibody titer Antibody titers assays binding capture Cell cells Clinical studies correlation COVID-19 degranulation demonstrated detect determine develop development Dilution dilution sery Efficiency effort elicited facilitate function functional antibody response healthy control high correlation Immunity IMPROVE infected cell infected cell. infected cells infected individuals magnitude moderate NK cell NK cell degranulation outcome overlap pandemic plasma platform ranged reduce response response rates responses SARS-CoV-2 SARS-CoV-2 disease SARS-COV-2 infection SARS-CoV-2 pandemic SARS-CoV-2-infected cell SARS-CoV-2-infected cells SARS-CoV-2-infected individual SARS-CoV-2-infected individuals Spearman the SARS-CoV-2 transfected cells Undetermined vaccination [DOI] 10.1002/cyto.a.24552 PMC 바로가기 [Article Type] Article
Mutational analysis of SARS-CoV-2 variants of concern reveals key tradeoffs between receptor affinity and antibody escape우려되는 SARS-CoV-2 변이체의 돌연변이 분석은 수용체 친화도와 항체 탈출 사이의 주요 트레이드오프를 보여줍니다Article Published on 2022-05-312022-09-11 Journal: PLoS Computational Biology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] ACE2 Analysis antibody Biotherapeutics capture complex concern concert domain expected global health Health human serum antibodies Impact IMPROVE machine learning model machine learning models modulate Mutation predict predicted RBD RBD mutation RBD mutations receptor Receptor-binding domain reduce reveal SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 mutations SARS-CoV-2 variant SARS-CoV-2 variants Transmissibility Vaccine variant Viral viral neutralization [DOI] 10.1371/journal.pcbi.1010160 PMC 바로가기 [Article Type] Article
Evaluation of Host Protein Biomarkers by ELISA From Whole Lysed Peripheral Blood for Development of Diagnostic Tests for Active Tuberculosis활동성 결핵 진단 테스트 개발을 위한 전 용해 말초 혈액에서 ELISA에 의한 숙주 단백질 바이오마커 평가Article Published on 2022-05-202022-09-11 Journal: Frontiers in Immunology [Category] 바이오마커, [키워드] analyses assay associative barrier Biomarker Biomarkers blood sample CALCOCO2 capture cause of death caused CD274 CD52 collected combinations complex conducted confirmatory tests consequence Control correlation country COVID-19 pandemic death defined development diagnosing Diagnosis diagnostic diagnostic test differentially expressed disease Diversity downregulated ELISA ENhance eradication evaluate expression GBP1 group groups Health Health crisis IFIT3 IFITM3 improvement Improvements incidence India individuals infected individuals Infection Infectious disease information investigated Key priorities key priority Laboratory Lateral flow device lysed negative controls nine Patient peripheral profile Protein protein expression Protein target protein targets qPCR Rapid reducing required ROC SAMD9L significantly SNX10 Stratification Test the WHO Tuberculosis validation study WHO World Health Organisation [DOI] 10.3389/fimmu.2022.854327 PMC 바로가기 [Article Type] Article
Evaluation of electropolymerized molecularly imprinted polymers (E-MIPs) on disposable electrodes for detection of SARS-CoV-2 in saliva타액에서 SARS-CoV-2 검출을 위한 일회용 전극의 전기중합 분자 각인 폴리머(E-MIP) 평가Article Published on 2022-05-082022-09-11 Journal: Analytica chimica acta [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] absence biosensor capture COVID-19 COVID-19 negative crosslinked demonstrated Electrochemical impedance spectroscopy Electrochemical polymerization evaluated functional isothermal LAMP limit of detection log Molecularly imprinted polymers monoclonal antibody monomer N,N'-methylenebisacrylamide National Health Service nine nucleic acid nucleic acid amplification Other respiratory viruses Patient PCA Polymer positive positive sample Principal component principal component analysis pseudoparticle respiratory respiratory viruses Saliva saliva samples SARS-CoV-2 selective selectivity specificity threshold threshold value transfer Treatment UK National Health Service virus [DOI] 10.1016/j.aca.2022.339777 PMC 바로가기 [Article Type] Article
Viral Antigen and Inflammatory Biomarkers in Cerebrospinal Fluid in Patients With COVID-19 Infection and Neurologic Symptoms Compared With Control Participants Without Infection or Neurologic Symptoms감염 또는 신경학적 증상이 없는 대조군과 비교하여 COVID-19 감염 및 신경학적 증상이 있는 환자의 뇌척수액에서 바이러스 항원 및 염증성 바이오마커Article Published on 2022-05-022022-09-11 Journal: JAMA Network Open [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료기술, 치료법, [키워드] 95% CI age Antigen Biomarker capture Central nervous system cerebrospinal fluid clinical CNS component Concentration contribute Control control group controls correlated COVID COVID-19 COVID-19 infection COVID-19 severity cross-sectional cross-sectional study CSF Cytokines detectable disease severity Encephalopathy Evidence evidence of Gothenburg Health Organization healthy control highlight IL-10 IL-6 immune activation immune response immune responses immunoassay Infection Inflammatory Inflammatory biomarker inflammatory biomarkers Injury interferon interferon γ interleukin IQR male median microglobulin moderate Moderate COVID-19 Necrosis neurologic neuronal no differences nucleocapsid antigen Older outcome participant Participants Pathogenesis Patient patient groups platform Principal component principal component analysis Protein Sahlgrenska University Hospital SARS-COV-2 infection SARS-CoV-2 nucleocapsid scale severe COVID-19 severe disease significantly significantly higher Study protocol Swedish Symptom Symptoms test results Tumor tumor necrosis tumor necrosis factor tumor necrosis factor α Viral Viral antigen viral invasion Viral RNA was performed with COVID-19 World Health Organization β2-microglobulin [DOI] 10.1001/jamanetworkopen.2022.13253 PMC 바로가기 [Article Type] Article
Seroprevalence of Infection-Induced SARS-CoV-2 Antibodies – United States, September 2021-February 2022감염 유도 SARS-CoV-2 항체의 혈청 유병률 - 미국, 2021년 9월-2022년 2월Article Published on 2022-04-292022-09-11 Journal: Morbidity and Mortality Weekly Report [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] age Asymptomatic B.1.1.529 capture cause CDC community survey COVID-19 COVID-19 case diagnosed Disease surveillance highest IMPROVE incidence of COVID-19 Laboratory National omicron peaked predominant proportion recorded SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 seroprevalence Seroprevalence survey The United States Traditional traditional methods United States variant of SARS-CoV-2 virus [DOI] 10.15585/mmwr.mm7117e3 PMC 바로가기 [Article Type] Article
Rapid Detection of Anti-SARS-CoV-2 Antibodies with a Screen-Printed Electrode Modified with a Spike Glycoprotein Epitope스파이크 당단백질 에피토프로 변형된 스크린 인쇄 전극을 사용한 항 SARS-CoV-2 항체의 신속한 검출Article Published on 2022-04-262022-09-11 Journal: Biosensors [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, 치료제, [키워드] 2019 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody B-cell epitope capture caused Chagas disease Chikungunya Consequences coronavirus coronavirus disease COVID-19 cross-reaction Dengue detection diagnose diagnoses diagnosing Diagnostic method differentiation dilution factor electrochemical biosensor electrode epitope Final flexibility Health hydroquinone IgG immunocomplex Immunoglobulin Immunoglobulin G immunological immunological diagnostic individual Infection linear material Molecular biology non-infected other disease other diseases pandemic Pathogens patient sera point of care Rapid reaction required respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike glycoprotein SARS-CoV-2-specific IgG SARS-CoV-2-specific IgGs selectivity sera serological serum samples severe acute respiratory syndrome Coronavirus specificity spike spike glycoprotein Spike protein Spread synthesis the SARS-CoV-2 the spike protein variants of SARS-CoV-2 Volume was measured was selected [DOI] 10.3390/bios12050272 PMC 바로가기 [Article Type] Article
DeepSARS: simultaneous diagnostic detection and genomic surveillance of SARS-CoV-2DeepSARS: SARS-CoV-2의 동시 진단 탐지 및 게놈 감시Article Published on 2022-04-112022-09-11 Journal: BMC Genomics [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단, 치료기술, 치료제, [키워드] Alpha Beta Biorender.com capture change deep sequencing diagnostic diagnostic testing diagnostics Diversity foundation genomic Genomic surveillance Image integration Large-scale testing molecular NGS PCR performed phylogenetics platform population level Quantitative SARS-CoV-2 Sequencing Spread Strains Surveillance tracing transmission rate Vaccine variant variants Viral Viral detection viral evolution whole genome Whole genome sequencing [DOI] 10.1186/s12864-022-08403-0 PMC 바로가기 [Article Type] Article