Advanced echocardiographic phenotyping of critically ill patients with coronavirus-19 sepsis: a prospective cohort studyResearch Published on 2021-01-202022-10-30 Journal: Journal of Intensive Care [Category] COVID-19, [키워드] Afterload alteration Biomarker cardiac cardiac dysfunction changes characterized clinical impact clinical implications clinical setting Cluster Concentration condition correlated COVID-19 COVID-19 patient COVID-19 sepsis Critically ill Critically ill patient echocardiographic echocardiographic parameter feasibility functions hemodynamic hierarchical clustering homogeneous incidence Interaction males management median age Mortality multivariable analysis myocardial injury parameter Patient physiological positively correlated prospective cohort study recorded Result Sepsis septic patients serum supplementary material therapeutic variable were assessed were measured [DOI] 10.1186/s40560-020-00516-6 PMC 바로가기 [Article Type] Research
Role of angiotensin-converting enzyme 2 and pericytes in cardiac complications of COVID-19 infectionArticle Published on 2020-11-012023-06-15 Journal: American journal of physiology. Heart and circulat [Category] MERS, SARS, [키워드] ACE2 cardiac dysfunction pericyte renin-angiotensin-aldosterone system SARS-CoV-2 [DOI] 10.1152/ajpheart.00681.2020 PMC 바로가기
The Yin and Yang of ACE/ACE2 Pathways: The Rationale for the Use of Renin-Angiotensin System Inhibitors in COVID-19 PatientsReview Published on 2020-07-162022-10-31 Journal: Cells [Category] COVID-19, SARS, [키워드] ACE ACE2 Administered Arm Asthma cardiac dysfunction Combination COVID-19 COVID-19 patient Critical downstream eosinophil hypertension Hypothesis hypoxia IL-10 in vivo inhibit inhibitor Lung fibrosis Mas receptor mechanisms pathway Patient positive positive feedback loop Prevent RAS rationale renin-angiotensin system SARS-CoV-2 severe acute respiratory syndrome coronavirus-2 Stage sustained System target the disease triggered upregulated [DOI] 10.3390/cells9071704 PMC 바로가기 [Article Type] Review
A Pharmacovigilance Study of Hydroxychloroquine Cardiac Safety Profile: Potential Implication in COVID-19 MitigationArticle Published on 2020-06-152022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% confidence interval adverse event Adverse reaction AEs Analysis analyzed Arrhythmias Atrioventricular block authorization calculate cardiac cardiac dysfunction Cardiomyopathy cardiovascular adverse events clinical benefits Clinical studies clinical study clinical trial Complete coronavirus disease COVID-19 database dataset determine diastolic drug dysfunction Effectiveness Efficacy Ejection fraction Emergency EUA FDA feasible food HCQ High dose higher risk highlight Hospitalized Hydroxychloroquine investigated Mitigation non-randomized Odds ratio outcome Patient patients performed pharmacovigilance pharmacovigilance analysis Potential predict QT prolongation Randomized Reactions receiving reported robust Safety subsequent therapy torsades de pointe torsades de pointes treatment regimen ventricular was used widespread with COVID-19 [DOI] 10.3390/jcm9061867 PMC 바로가기 [Article Type] Article
ACE2 and COVID-19: using antihypertensive medications and pharmacogenetic considerationsReview Published on 2020-06-052022-10-28 Journal: Pharmacogenomics [Category] COVID-19, [키워드] ACE-inhibition ACE2 ACE2 pathway Alter angiotensin-receptor blockade angiotensinogen antihypertensive medication cardiac dysfunction clinically Comorbidity contribute coronavirus COVID-19 death demographic genetic component Genomics heterogeneity heterogenous Hypertension medication Infection modulation no symptom patients with COVID-19 pharmacogenetic protective effect RAAS Renin Respiratory failure Severity of infection severity of symptom shown Transmission variant [DOI] 10.2217/pgs-2020-0048 PMC 바로가기 [Article Type] Review
Vivax malaria in an Amazonian child with dilated cardiomyopathy아마존 어린이의 확장형 심근병증에서 비박스 말라리아Case Report Published on 2014-02-182024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Amazon cardiac dysfunction cytomegalovirus infection dilated cardiomyopathy vivax malaria [DOI] 10.1186/1475-2875-13-61 PMC 바로가기 [Article Type] Case Report