CD4+ T cells – Page 2 – Communicable Diseases Research

Contribution of CD4+ T cell-mediated inflammation to diarrhea in patients with COVID-19

COVID-19 환자의 설사에 대한 CD4+ T 세포 매개 염증의 기여

Article

Published on 2022-07-012022-09-11
Journal: International Journal of Infectious Diseases [Category] Coronavirus, COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 치료기술,

Peptidome Surveillance Across Evolving SARS-CoV-2 Lineages Reveals HLA Binding Conservation in Nucleocapsid Among Variants With Most Potential for T-Cell Epitope Loss in Spike

진화하는 SARS-CoV-2 계통에 걸친 펩티도돔 감시, 스파이크에서 T 세포 에피토프 손실 가능성이 가장 큰 변이체 중 뉴클레오캡시드에서 HLA 결합 보존 밝혀

Article

Published on 2022-06-232022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, 치료법,

[키워드] Analysis Antigen B.1.1.529 binding candidate caused CD4+ T cell CD4+ T cells CD8+ comprehensive analysis concern conservation conserved Course COVID-19 disease dominant elicit epitope Epitopes Evidence Genome GISAID heterogeneity HLA immune response immune responses instance interest lineages Loss MOST Mutation N protein N proteins NCBI NIH nucleocapsid omicron pandemic peptide peptides performed Potential predicted Protein protein sequence provided Region remained S protein SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 lineage spike sustained T cells T-cell the N protein the S protein unique vaccination variant variants viral evolution viral variant Viral variants VoC VOCs Volume
[DOI] 10.3389/fimmu.2022.918928 PMC 바로가기 [Article Type] Article

CD4+ T-Cell Dysfunction in Severe COVID-19 Disease Is Tumor Necrosis Factor-α/Tumor Necrosis Factor Receptor 1-Dependent

Article

Published on 2022-06-152023-07-08
Journal: American Journal of Respiratory and Critical Care [Category] COVID19(2023년),

[키워드] CD4+ T cells COVID-19 lymphopenia SARS-COV-2 infection TNF-α
[DOI] 10.1164/rccm.202111-2493OC PMC 바로가기

SARS-CoV-2 vaccination diversifies the CD4+ spike-reactive T cell repertoire in patients with prior SARS-CoV-2 infection

SARS-CoV-2 백신 접종은 이전 SARS-CoV-2 감염 환자에서 CD4+ 스파이크 반응성 T 세포 레퍼토리를 다양화합니다.

Article

Published on 2022-06-012022-09-12
Journal: EBioMedicine [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] activated analyzed B cell response CD4+ CD4+ T cell CD4+ T cells clone common cold coronavirus coronavirus Coronaviruses COVID-19 COVID-19 convalescent patient COVID-19 disease demonstrated elicit expansion foundation healthy donor identify immune response induce Johns Hopkins University Melinda Gate mRNA mRNA vaccination mRNA vaccine naïve natural infection NIH Patient patients Post-vaccine question reactive receptor recipients response SARS-CoV-2 SARS-CoV-2 antigens SARS-COV-2 infection SARS-CoV-2 vaccination Specific spike glycoprotein stimulated T cell T cell receptor the SARS-CoV-2 the vaccine vaccination Vaccine
[DOI] 10.1016/j.ebiom.2022.104048 PMC 바로가기 [Article Type] Article

Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection

T 세포 수용체 레퍼토리의 종단 분석은 SARS-CoV-2 감염에 대한 항원 특이적 반응의 공유 패턴을 보여줍니다

Article

Published on 2022-05-232022-09-11
Journal: JCI Insight [Category] COVID19(2023년), SARS, 치료기술,

Clinical Significance of BTLA and HVEM Expression on Circulating CD4+ T and CD8+ T Cells in Chronic Hepatitis B Virus Infection

Article

Published on 2022-05-012023-06-13
Journal: Viral immunology [Category] B형 간염,

[키워드] B and T lymphocyte CD4+ T cells CD8+ T cells Chronic hepatitis B virus infection herpesvirus entry mediator.
[DOI] 10.1089/vim.2021.0134

Short Communication: S100A8 and S100A9, Biomarkers of SARS-CoV-2 Infection and Other Diseases, Suppress HIV Replication in Primary Macrophages

Article

Published on 2022-05-012023-07-07
Journal: AIDS research and human retroviruses [Category] COVID19(2023년),

[키워드] CD4+ T cells Monocyte-derived macrophages S100A8 S100A9
[DOI] 10.1089/AID.2021.0193 PMC 바로가기

In-depth analysis of SARS-CoV-2-specific T cells reveals diverse differentiation hierarchies in vaccinated individuals

SARS-CoV-2-특이적 T 세포에 대한 심층 분석은 백신 접종을 받은 개인의 다양한 분화 계층을 보여줍니다

Article

Published on 2022-04-082022-09-11
Journal: JCI Insight [Category] COVID19(2023년), SARS, 변종, 치료기술,

[키워드] Adaptive immune response Adaptive immunity Analysis approach breadth Breakthrough infection breakthrough infections CD4+ T cell CD4+ T cells clinical trial clinical trials COVID-19 COVID-19 pandemic cytokine profile determinant effective Efficacy feature fraction Fractions identify IL-2 immune immunology indicate individual induce investigated Last Longevity magnitude majority mutant produced reactive recall Region responders reveal S-protein SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 vaccines SARS-CoV-2-specific T cell SARS-CoV-2-specific T cells T cell T cell response T cells TNF-α vaccinated individual vaccinated individuals vaccination Vaccine variants of concern
[DOI] 10.1172/jci.insight.156559 PMC 바로가기 [Article Type] Article

Deciphering the Plasmodium falciparum malaria-specific CD4+ T-cell response: ex vivo detection of high frequencies of PD-1+TIGIT+ EXP1-specific CD4+ T cells using a novel HLA-DR11-restricted MHC class II tetramer

Article

Published on 2022-04-042024-08-28
Journal: Clinical and Experimental Immunology [Category] 말라리아,

[키워드] CD4+ T cells host–pathogen interactions Immune checkpoints inhibitory/activating receptors parasitic-protozoan.

Assessment of T-cell Reactivity to the SARS-CoV-2 Omicron Variant by Immunized Individuals

면역화된 개인에 의한 SARS-CoV-2 오미크론 변이체에 대한 T 세포 반응성 평가

Article

Published on 2022-04-012022-09-11
Journal: JAMA Network Open [Category] COVID19(2023년), SARS, 변종,

[키워드] age assessment blood sample Blood samples Care CD4+ cell CD4+ cells CD4+ T cell CD4+ T cells CD8+ T cells Cell cellular component cellular immunity cohort study conducted contagious decrease determine enrolled foundation Frequency full-length protein group Health Health care highlight Hospitalization immune immune protection immune system Immunity immunized individual Infection Italy Lymphocytes median mutated Mutation Neutralizing new SARS-CoV-2 no significant differences omicron Omicron variant outcome participant peptide peptides reactive reactivity reduced reduction Region regions Rome SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant sera severe disease significant difference significantly Spike protein Stimulation T cells T-cell T-cell immunity tested the SARS-CoV-2 the spike protein vaccination variant variant of SARS-CoV-2 Volunteer volunteers women
[DOI] 10.1001/jamanetworkopen.2022.10871 PMC 바로가기 [Article Type] Article