A split influenza vaccine formulated with a combination adjuvant composed of alpha-D-glucan nanoparticles and a STING agonist elicits cross-protective immunity in pigsArticle Published on 2022-11-112023-06-14 Journal: Journal of Nanobiotechnology [Category] Fulltext, 신종인플루엔자, [키워드] ADU-S100 cellular immunity Nano-11 PIGS Swine influenza A viruses vaccination. [DOI] 10.1186/s12951-022-01677-2 PMC 바로가기
Reduced humoral but stable cellular SARS-CoV-2-specific immunity in liver transplant recipients in the first year after COVID-19Article Published on 2022-11-022022-11-15 Journal: PLoS ONE [Category] SARS, 진단, 치료기술, [키워드] anti-Nucleocapsid IgG anti-SARS-CoV-2 anti-SARS-CoV-2 IgG antibody Antigen booster vaccination cellular cellular immunity Cohort Concentration convalescent COVID-19 detectable domain Endemic humoral IFN-γ IgG immune response Immunity Immunoglobulin Immunosuppressed Immunosuppression immunosuppressive individual liver Liver transplantation membrane nucleocapsid Prevalence protective immunity reactivity Receptor binding domain recipient remained retrieved robust SARS-CoV-2 significantly increased Spike protein stimulated T cell T cell response therapy vaccination [DOI] 10.1371/journal.pone.0276929 PMC 바로가기
Measuring SARS-CoV-2 T cell immunity with a scalable qPCR-based assayArticle Published on 2022-11-012022-11-16 Journal: Nature biotechnology [Category] SARS, 치료기술, [키워드] cellular immunity CXCL10 detect Immunity mRNA PCR-based assay Quantitative SARS-CoV-2 T cell T cell response viral peptides Whole blood [DOI] 10.1038/s41587-022-01358-3 PMC 바로가기
Interferon α facilitates anti-HBV cellular immune response in a B cell-dependent mannerArticle Published on 2022-11-012023-06-13 Journal: Antiviral Research [Category] B형 간염, [키워드] B cell cellular immunity Hepatitis B virus IFN-α T cell. [DOI] 10.1016/j.antiviral.2022.105420 PMC 바로가기
Concordance of B- and T-cell responses to SARS-CoV-2 infection, irrespective of symptoms suggestive of COVID-19Article Published on 2022-11-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 진단, [키워드] absence Analysis anti-IgG antibodies antibody Antibody titer Cellular immune response cellular immunity Cohort correlated correlated strongly COVID COVID-19 COVID-19 pandemic ELISA Evidence Final First wave IgG individual pandemic participant positive antibody response Regulatory response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 peptide SARS-CoV2 infection spike Symptom symptom response. symptomatic and asymptomatic T cell T-cell T-cell Response TwinsUK were assessed [DOI] 10.1002/jmv.28016 PMC 바로가기
Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccinationArticle Published on 2022-10-282022-11-15 Journal: Science Immunology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Antibody Response B.1.617.2 BAL Blood booster vaccination Breakthrough infection Bronchoalveolar lavage fluid cellular immunity circulating Combination convalescent COVID-19 COVID-19 vaccine D614G Delta demonstrated effective elicit hospitalized patients humoral immune response Immunity immunization individual induce Infection mRNA vaccination mucosal neutralizing antibody Neutralizing antibody response neutralizing antibody responses offer omicron Reinfection respiratory respiratory tract response robust SARS-CoV-2 severe disease significantly lower Support T cell T cell response the SARS-CoV-2 vaccinated individuals variant variants of concern virus VOCs with COVID-19 [DOI] 10.1126/sciimmunol.add4853 PMC 바로가기
CD8+ T-cell immune escape by SARS-CoV-2 variants of concernReview Published on 2022-10-272023-07-10 Journal: Frontiers in Immunology [Category] COVID19(2023년), [키워드] CD8 + T-cell epitope cellular immunity cytotoxic T lymphocytes (CTL) HLA Immune escape protein mutation SARS-CoV-2 Variant of concern (VOC). [DOI] 10.3389/fimmu.2022.962079 PMC 바로가기 [Article Type] Review
Boosting with Multiple Doses of mRNA Vaccine after Priming with Two Doses of Protein Subunit Vaccine MVC-COV1901 Elicited Robust Humoral and Cellular Immune Responses against Emerging SARS-CoV-2 VariantsArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome antibody AZD1222 booster vaccination cellular Cellular immune response cellular immune responses cellular immunity coronavirus COVID-19 Delta delta variant dose effective elevated elicit Emergency use authorization emerging variants evaluated Evidence Heterologous heterologous prime-boost heterologous vaccination humoral immune immune evasion immune response immune responses IMPROVE increase in induce Infection interferon mRNA mRNA vaccine mRNA-1273 Multiple Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody omicron Prevent priming promote Protein subunit protein subunit vaccine provided RBD Receptor binding domain reduced regimen response SARS-CoV-2 SARS-CoV-2 variants significantly subunit suggested T cell Taiwan vaccination vaccination schedule Vaccine variant variants Viral variants Viral variants. wild type [DOI] 10.1128/spectrum.00609-22 PMC 바로가기
Impact of the New Coronavirus Infection on the Immune System of Children and Adolescents in the Region of the Russian FederationArticle Published on 2022-10-212022-11-15 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 진단, [키워드] absence Active disease Adolescent age analysed analyses Analysis biochemical carried categories caused CD3+CD4+ cellular immunity changes in children Clinical features consequence COVID-19 deviation Diagnosis disease disease stage Epidemiology Federation FIVE flow cytometry group growth Human immune system IgA IgG IgG and IgM IgM Immune status immune system Immunity Immunoglobulin immunograms immunological immunology immunology. immunoregulation Impact Infection interval introduced laboratory diagnosis lack leukocytes Lymphocytes methodology Mutation New New coronavirus NK cell pandemic pathogen Patient patients Perm Krai phagocytic phagocytosis professional public health QR code Quantitative analysis Racial Region Research Russian population SARS-CoV-2 SARS-CoV-2 vaccination selected serological severity System T helper the disease Treatment was performed [DOI] 10.3390/ijerph192013669 PMC 바로가기
Effectiveness of COVID-19 vaccination in healthcare workers in Shiga Prefecture, JapanArticle Published on 2022-10-212022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 진단, [키워드] Abbott analyzed antibody Cell cells Cellular immune response cellular immunity conducted coronavirus disease COVID-19 COVID-19 vaccination COVID-19 vaccinations Delta effective evaluated HCW HCWs health condition healthcare worker Hospitalization humoral induce Japan Poor questionnaire repeated required Roche SARS-CoV-2 SARS-COV-2 infection serological seropositive Standard deviation vaccination Vaccine Wuhan-1 [DOI] 10.1038/s41598-022-22682-3 PMC 바로가기