Clocks, Viruses, and Immunity: Lessons for the COVID-19 Pandemic시계, 바이러스 및 면역: COVID-19 팬데믹에 대한 교훈Review Published on 2021-01-222022-09-10 Journal: Journal of Biological Rhythms [Category] MERS, 유전자 메커니즘, [키워드] Antiviral Biological Biological Rhythms chronobiology chronotherapy circadian clock circadian rhythm circadian rhythms CLOCK conserved COVID-19 European Evidence Host host responses host susceptibility Immunity knowledge lesson mechanisms pandemic Pathogenesis Research Research question Resilience respond rhythm SARS-CoV-2 Society Support Therapeutic strategies therapeutic strategy threat Threats translational Viral viral infection viral infections viral replication viruses [DOI] 10.1177/0748730420987669 PMC 바로가기 [Article Type] Review
Hydrogen: A Novel Option in Human Disease TreatmentReview Article Published on 2020-09-052022-10-29 Journal: Oxidative Medicine and Cellular Longevity [Category] COVID-19, MERS, SARS, [키워드] Anti-inflammatory antioxidant Apoptosis autophagy cell death Chinese circadian clock clinical Clinical treatment clinical trials disease Diseases Endoplasmic reticulum energy metabolism experiment extrapulmonary organ Ferroptosis Human immune system lung mitochondrial Multiorgan novel Novel coronavirus option patients Pneumonia potential mechanism PROTECT pyroptosis regulate Research shown Stress systemic diseases therapeutic potential treatment guidelines [DOI] 10.1155/2020/8384742 PMC 바로가기 [Article Type] Review Article
COVID-19 management in light of the circadian clock Comments & Opinion Published on 2020-07-222022-10-05 Journal: Nature Reviews Molecular Cell Biology [Category] SARS, 치료제, [키워드] circadian clock COVID-19 management [DOI] 10.1038/s41580-020-0275-3 [Article Type] Comments & Opinion
Periodic Parasites and Daily Host RhythmsArticle Published on 2020-02-122024-08-28 Journal: Cell Host & Microbe [Category] 말라리아, [키워드] circadian clock circadian rhythm entrainment fitness host-parasite interactions Inflammatory response intra-erythrocytic development cycle metabolism nutrient sensing Periodicity Plasmodium synchronicity.
Cell Type-Specific Functions of Period Genes Revealed by Novel Adipocyte and Hepatocyte Circadian Clock Models새로운 지방세포 및 간세포 일주기 시계 모델에 의해 밝혀진 기간 유전자의 세포 유형별 기능Research Article Published on 2014-04-032022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adipocytes Affect amplitude animals Behavior biochemical Bmal1 Brain Cell cell types cellular circadian clock circadian rhythms CLOCK component Cry1 Cry2 Effect evaluated expected Families feasible fibroblasts function Gene Expression Genes Genetic genomic hepatocyte hepatocytes hypothalamus Impact implication Interaction kinetic knockdown knockout mice lentivirus library Local Luminescence mechanism metabolism microplate reader Model molecular negative feedback negative feedback mechanism neurons novel nuclei Per1 Per2 PER3 Period phenotype Physiology Previous studies regulated reporter reveal Revealed RNA RNA interference small molecule Small molecules tissue specific transcriptional [DOI] 10.1371/journal.pgen.1004244 PMC 바로가기 [Article Type] Research Article