Encephalopathy as a prognostic factor in adults with acute disseminated encephalomyelitis following COVID-19COVID-19에 따른 급성 파종성 뇌척수염 성인의 예후 인자로서의 뇌병증Case Reports Published on 2022-05-012022-09-11 Journal: Journal of Neurology [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI absence Acute disseminated encephalomyelitis Acute necrotizing hemorrhagic leukoencephalitis ADEM affected ANHLE cerebrospinal fluid Clinical outcome clinical variable clinical variables COVID-19 Descriptive analysis Disseminated encephalomyelitis Encephalomyelitis Encephalopathy females Hemorrhagic Hemorrhagic Leukoencephalitis Infection Logistic regression median age morbidity and mortality Mortality Neurological symptoms Numerous observation Occurrence other variable other variables outcomes Patient patients performed predict Prognostic factor Prognostic factors proportion retrospective SARS-CoV-2 SARS-COV-2 infection Support Treatment variant worse prognosis [DOI] 10.1007/s00415-021-10947-2 PMC 바로가기 [Article Type] Case Reports
Fourth Dose of BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting전국적인 환경에서 BNT162b2 mRNA 코비드-19 백신의 4차 접종Comparative Study Published on 2022-04-132022-09-25 Journal: The New England Journal of Medicine [Category] COVID19(2023년), SARS, 변종, 진단, 치료법, [키워드] 95% CI 95% confidence interval acute respiratory syndrome age analyzed B.1.1.529 BNT162b2 vaccine booster dose Care clinical variables collaboration coronavirus coronavirus disease country death dose doses driven by effective Effectiveness estimate evaluate evaluated Evidence family Francesca Harvard Medical School Health Hospitalization Infection mRNA of BNT162b2 Older outcome outcomes Poisson regression primary analysis recorded reducing relative Result risk SARS-CoV-2 SARS-COV-2 infection Sensitivity analyses sensitivity analysis setting Sociodemographic symptomatic COVID-19 two group Vaccine vaccine dose variant waning immunity was performed [DOI] 10.1056/NEJMoa2201688 PMC 바로가기 [Article Type] Comparative Study
Effect of tocilizumab versus standard of care in adults hospitalized with moderate-severe COVID-19 pneumonia중등도 중증 COVID-19 폐렴으로 입원한 성인에서 표준 치료 대비 토실리주맙의 효과Observational Study Published on 2022-04-082022-09-12 Journal: Medicina clínica [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] administration Admission adults hospitalized analyses Analysis association clinical variables coefficient Cohort cohort of patients control group COVID-19 COVID-19 patient did not reduce Effect Efficacy English Estudio observacional Hebron hospitalized COVID-19 ICU interleucina 6 interleukin-6 Logistic regression LOS moderate-severe Mortalidad Mortality Neumonía observational study outcome overall mortality Patient patients with COVID-19 patients with moderate Pneumonia Propensity-score-matched PSM receiving receptor retrospective risk secondary selected severe COVID-19 Sin Spanish Standard of care therapy Tocilizumab tocilizumab administration treated Treatment variable was performed [DOI] 10.1016/j.medcli.2021.03.005 PMC 바로가기 [Article Type] Observational Study
Developing a shared sepsis data infrastructure: a systematic review and concept map to FHIR Research Published on 2022-04-042022-10-05 Journal: NPJ Digital Medicine [Category] 바이오마커, [키워드] analyzed approach Awareness clinical care clinical variable clinical variables condition Consensus core COVID-19 criteria described develop Developing disease element English excluded extension flexible Health health system highlighting hospital identify IMPROVE interoperability lack manuscript mapped provided public health required Research resource Sepsis Septic shock spectrum of diseases subtype Subtypes systematic review to define unique variable yielding [DOI] 10.1038/s41746-022-00580-2 [Article Type] Research
Anxiety and depression in patients with advanced cancer during the COVID-19 pandemicCOVID-19 전염병 동안 진행된 암 환자의 불안과 우울증Multicenter Study Published on 2022-04-012022-09-11 Journal: Supportive Care in Cancer [Category] COVID19(2023년), SARS, 치료기술, [키워드] Advanced cancer age Anxiety association Cancer Cancer patients cancer type children clinical variables Cohort consecutive patient COVID-19 COVID-19 pandemic Depression diagnosed Diagnosis distress early diagnosis Effect emotional distress Factor female greater higher risk histology Hope hopelessness Hopelessness. illness incidence increased risk index initiated Intervention inventory linear regression analyses Linear regression analysis marital status multicenter no differences pandemic Patient Psychological psychological factors regression analysis scale Sociodemographic Stage subgroups survival Treatment Uncertainty women Worry [DOI] 10.1007/s00520-021-06789-3 PMC 바로가기 [Article Type] Multicenter Study
Antibody Responses to Severe Acute Respiratory Syndrome Coronavirus 2 in the Serum and Cerebrospinal Fluid of Patients With Coronavirus Disease 2019 and Neurological Symptoms코로나바이러스 질환 2019 및 신경학적 증상이 있는 환자의 혈청 및 뇌척수액에서 중증 급성 호흡기 증후군 코로나바이러스 2에 대한 항체 반응Article Published on 2022-03-152022-09-11 Journal: The Journal of Infectious Diseases [Category] MERS, SARS, 바이오마커, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Antibody Response Antibody responses Central nervous system cerebrospinal fluid clinical variables coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 CSF disease severity elevated highest IgG Immunoglobulin Immunoglobulin G independent Level marker neurological Neurological symptom Neurological symptoms neuronal Patient Predictive Predictive value respiratory response SARS-CoV-2 SARS-CoV-2 IgG serological serology serum severe acute respiratory syndrome Coronavirus Spike protein tested virus spike protein were assessed [DOI] 10.1093/infdis/jiab153 PMC 바로가기 [Article Type] Article
Strain Echocardiography and Myocardial Dysfunction in Critically Ill Children With Multisystem Inflammatory Syndrome Unrecognized by Conventional Echocardiography: A Retrospective Cohort Analysis기존의 심장초음파로는 인식되지 않는 다기관 염증 증후군이 있는 중증 소아의 긴장성 심장초음파 및 심근 기능 장애: 후향적 코호트 분석Observational Study Published on 2022-03-012022-09-11 Journal: Pediatric critical care medicine : a journal of th [Category] SARS, 임상, 치료기술, [키워드] 95% CI Abnormalities abnormality acute respiratory syndrome association Biomarker Biomarkers cardiac cardiac function Cardiogenic shock Care children clinical clinical outcomes clinical variables Conventional coronavirus correlated Critically ill defined detect Deterioration Diagnosis dysfunction Early detection echocardiography Ejection fraction examined greater highest ICU identify Ill immune imperative Infection Inflammatory Intensive intensive care Intervention left ventricular ejection fraction less measurement Myocardial dysfunction Observational cohort study Odds ratio outcomes Patient pediatric Pediatric patient Respiratory Support risk Shock statistic strain syndrome therapeutic Therapies therapy variable Vasoactive ventricular ventricular ejection was measured [DOI] 10.1097/PCC.0000000000002850 PMC 바로가기 [Article Type] Observational Study
Multiscale PHATE identifies multimodal signatures of COVID-19 Research Published on 2022-02-282022-10-05 Journal: Nature biotechnology [Category] 유전자 메커니즘, 치료법, [키워드] analyzed Cell chromatin Classifier clinical variables Community complex computational tool coronavirus disease COVID-19 dataset diffusion disease feature flow cytometry granularity hospitalized patient identify increasingly neutrophil outcome Patient predict Predictive responses scRNA-seq Sequencing single-cell Single-cell RNA sequencing Th17 Topology [DOI] 10.1038/s41587-021-01186-x [Article Type] Research
The CCEDRRN COVID-19 Mortality Score to predict death among nonpalliative patients with COVID-19 presenting to emergency departments: a derivation and validation studyCCEDRRN COVID-19 사망률 점수를 통해 응급실에 내원한 비완화성 COVID-19 환자의 사망 예측: 파생 및 검증 연구Article Published on 2022-02-082022-09-11 Journal: CMAJ open [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval age assigned assist can be used Canada Cardiopulmonary Cardiopulmonary resuscitation Care chest pain circulating clinical variable clinical variables Cohort COVID-19 Critical care death Department derivation develop died Eligible patients Emergency emergency department examined hospital In-hospital death in-hospital mortality in-hospital mortality rate information intensive care intubation less Liver disease Logistic regression Measures Mortality mortality rate Negative predictive value network Patient patients patients with COVID-19 predict Predictive value predictors presenting Randomly Rapid recruited residence resource resources respiratory rate Respiratory Support response risk score severe liver disease Sex treatment regimen validation cohort validation study variable variants variants of concern [DOI] 10.9778/cmajo.20210243 PMC 바로가기 [Article Type] Article
Sociodemographic and clinical characteristics of paediatric patients admitted to a neuropsychiatric care hospital in the COVID-19 eraObservational Study Published on 2022-02-052022-10-04 Journal: Italian Journal of Pediatrics [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] activity addition adolescents age analysed Care caused change changed Chi square test children Clinical characteristics clinical variables COVID COVID-19 COVID-19 group COVID-19 pandemic decrease developmental disorders Effect Effects epidemiological event Factor greater Health health emergency hospital hospitalisation hospitalised increase in Inpatient Italy mental health Mental health disorder Neuropsychiatric neuropsychiatric disease neuropsychiatry North occurred Paediatric age paediatric patient Patient percentages pharmacological physical Prevalence problem psychiatric disorder recruited Result retrospective cohort Sociodemographic Standard deviation t-test therapy unit [DOI] 10.1186/s13052-022-01213-w PMC 바로가기 [Article Type] Observational Study