Effect of colchicine on the outcomes of patients with COVID-19: a systematic review and meta-analysis of randomised controlled trialsCOVID-19 환자의 결과에 대한 콜히친의 영향: 무작위 대조 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-12-012022-09-11 Journal: Annals of Medicine [Category] 임상, [키워드] 95% CI addition adverse event adverse events Clinical efficacy clinical outcomes ClinicalTrials Cochrane Library Colchicine control group COVID-19 database diarrhoea Effect higher risk hospital Hospital stay improve clinical outcome mean difference mechanical ventilation Meta-analysis Mortality no significant difference non-invasive ventilation not reduce Odds ratio outcome OVID Patient patients with COVID-19 Placebo placebos randomised controlled trial RCT RCTs receiving risk SARS-CoV-2 searched significant difference significantly higher standard treatment study group Support systematic review the study group Treatment Web of Science [DOI] 10.1080/07853890.2022.2096919 PMC 바로가기 [Article Type] Meta-Analysis
Impact of colchicine on mortality and morbidity in COVID-19: a systematic reviewArticle Published on 2022-12-012023-07-08 Journal: Annals of Medicine [Category] COVID19(2023년), [키워드] Colchicine coronavirus COVID-19 [DOI] 10.1080/07853890.2021.1993327 PMC 바로가기
Interleukin-1 and the NLRP3 inflammasome in COVID-19: Pathogenetic and therapeutic implicationsReview Published on 2022-11-012023-07-10 Journal: EBioMedicine [Category] COVID19(2023년), [키워드] Anakinra C-reactive protein canakinumab Colchicine COVID-19 IL-18 IL-1β NLRP3 inflammasome SARS-CoV-2 [DOI] 10.1016/j.ebiom.2022.104299 PMC 바로가기 [Article Type] Review
Comparative efficacy and safety of pharmacological interventions for severe COVID-19 patients: An updated network meta-analysis of 48 randomized controlled trialsArticle Published on 2022-10-142022-11-15 Journal: Medicine [Category] meta-analysis, 진단, [키워드] Abstract ACM all-cause mortality Characteristics Colchicine Comparative convalescent plasma database decrease dosage effective Efficacy and safety hyperimmune Imatinib Immunoglobulin Intravenous immunoglobulin medication Methylprednisolone Network meta-analysis Older participant Patient pharmacological intervention Placebo Randomized controlled trial RCT RCTs Remdesivir Safe sarilumab searched severe COVID-19 Severe COVID-19 Infection severe COVID-19 patients suggested TEAE TEAEs treatment-emergent adverse event Trial [DOI] 10.1097/MD.0000000000030998 PMC 바로가기
Adding colchicine to tocilizumab in hospitalized patients with severe COVID-19 pneumonia: An open-label randomized controlled trialArticle Published on 2022-09-302022-11-15 Journal: Medicine [Category] SARS, 진단, [키워드] 1:1 added Adding Analysis antagonists Anti-inflammatory anti-inflammatory agent approved cascade center Colchicine Corporation cytokine Cytokine storm Efficacy and safety Ethics evaluate hospitalized patient IL-6 IL-6 blockade include Inflammasome inhibiting institutional review board Invasive mechanical ventilation Local mechanism of action Mortality NLRP3 Open-label Patient peer-reviewed Primary outcome Randomized Randomized controlled trial receptor receptor protein reduce Result risk safety profile severe COVID-19 Severe COVID-19 pneumonia Study protocol submitted Tocilizumab upstream [DOI] 10.1097/MD.0000000000030843 PMC 바로가기
Clinical course of Covid-19 in a cohort of patients with Behçet diseaseResearch article Published on 2022-09-012022-10-05 Journal: Medicina clínica [Category] 임상, [키워드] age Ageusia Behçet disease clinical Clinical outcome clinical outcomes clinical symptom cohort of patient Colchicine conducted Continuous Course COVID-19 demographics disease dose Dyspnea General population glucocorticoid Glucocorticoids implication Infection inhibitor long-term treatment Medical conditions Necrosis no significant difference objective Patient patients Prevalence provided questionnaire reduced Result Retrospective study significantly higher Spain tested therapeutic agent therapy Tumor necrosis factor alpha inhibitor [DOI] 10.1016/j.medcli.2021.11.009 [Article Type] Research article
Clinical impact and disease evolution of SARS-CoV-2 infection in familial Mediterranean feverArticle Published on 2022-08-012023-07-09 Journal: Pharmacological research [Category] COVID19(2023년), [키워드] Autoinflammation Colchicine Familial Mediterranean fever Innovative biotechnologies interleukin-1 Personalized medicine SARS-COV-2 infection [DOI] 10.1016/j.phrs.2022.106293 PMC 바로가기
High-cited favorable studies for COVID-19 treatments ineffective in large trialsResearch article Published on 2022-08-012022-10-05 Journal: Journal of clinical epidemiology [Category] 신약개발, 유전자 메커니즘, 임상, 치료법, [키워드] Altmetric article benefit bias citation citations clinical study clinical trial Colchicine convalescent plasma coronavirus disease correlated correlated strongly COVID-19 COVID-19 treatment Critical Effectiveness eligible evaluate examined Features Hydroxychloroquine interferon Intervention large trial Lopinavir-ritonavir nine Nonrandomized studies objective observational study patients Randomized controlled trial Randomized controlled trials randomized trial RCT RCTs Remdesivir Result setting Study design subsequent Treatment [DOI] 10.1016/j.jclinepi.2022.04.001 [Article Type] Research article
Treatment strategies of COVID-19: A rheumatology perspectiveCOVID-19의 치료 전략: 류마티스학적 관점Review Published on 2022-08-012022-09-12 Journal: European journal of internal medicine [Category] COVID19(2023년), SARS, 진단, 치료법, 치료제, [키워드] absence acute respiratory syndrome adaptive approved authority Colchicine Coronavirus-2 Corticosteroid COVID-19 Critical Critically ill patient Dexamethasone DMARDs effective host cell Immunity Inflammatory response inhibitors interleukin-6 janus Kinase inhibitor mAbs monoclonal antibody off-label Perspective plethora progression Proinflammatory cytokine Remdesivir Replication rheumatologist rheumatology SARS-CoV-2 SARS-CoV-2 mAbs. SARS-CoV-2 pneumonia therapeutic strategy Treatment viral entry [DOI] 10.1016/j.ejim.2022.05.014 PMC 바로가기 [Article Type] Review
Recurrent Myocarditis Treated with Intravenous Immune Globulin and Steroids정맥 면역 글로불린 및 스테로이드로 치료하는 재발성 심근염Case Reports Published on 2022-07-082022-09-12 Journal: The American journal of case reports [Category] MERS, 진단, [키워드] Admission Chest chest pain clinically suspected Colchicine coronary syndrome COVID diagnosed Diagnosis Evidence Globulin healthy hospital immunosuppressive incidence indicated Infection Inflammatory inflammatory process intensive care unit Intravenous immunoglobulin magnetic resonance imaging mimicking MOST MRI myocarditis Myocardium pandemic Patient Recurrent reported resolved steroid Symptom The United States therapy transferred treated troponin I viral infection [DOI] 10.12659/AJCR.935974 PMC 바로가기 [Article Type] Case Reports