Convalescent patients – Page 2 – Communicable Diseases Research

Transient and durable T cell reactivity after COVID-19

COVID-19 이후 일시적이고 지속적인 T 세포 반응성

Article

Published on 2022-07-262022-09-11
Journal: Proceedings of the National Academy of Sciences of [Category] COVID19(2023년), MERS, SARS, 진단, 치료법,

Kinetics of anti-nucleocapsid IgG response in COVID-19 immunocompetent convalescent patients

COVID-19 면역적격 회복기 환자에서 항뉴클레오캡시드 IgG 반응의 동역학

Article

Published on 2022-07-202022-09-11
Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법,

[키워드] absence anti-Nucleocapsid IgG anti-SARS-CoV-2 anti-SARS-CoV-2 humoral antibody Antibody Response Antibody testing BMI comprehension convalescent patient Convalescent patients country COVID-19 COVID-19 convalescent patient COVID-19 disease decrease detectable develop disease severity humoral humoral immune response IgG IgG antibodies IgG antibody immunodeficiency inclusion criteria Kinetics knowledge longitudinal study majority Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples nucleocapsid Patient positive Protein Re-infection robust RT- PCR SARS-CoV-2 SARS-CoV-2 nucleocapsid serum Sex Treatment Vaccination strategies Vaccination strategy virus infection
[DOI] 10.1038/s41598-022-16402-0 PMC 바로가기 [Article Type] Article

The Cellular Characterization of SARS-CoV-2 Spike Protein in Virus-Infected Cells Using the Receptor Binding Domain Binding Specific Human Monoclonal Antibodies

수용체 결합 도메인 결합 특이적 인간 단일클론 항체를 사용하여 바이러스에 감염된 세포에서 SARS-CoV-2 스파이크 단백질의 세포 특성화

Article

Published on 2022-07-132022-09-11
Journal: Journal of Virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] adopted antibody appearance appears attachment B cell B cells biological properties biological property can be used Cell cell-to-cell transmission characterization conformation conformational change convalescent COVID-19 patient convalescent COVID-19 patients convalescent patient convalescent patient serum Convalescent patients cytoplasmic demonstrated early stage early stages electron microscopy epitope Epitopes Evidence exhibited FIVE focus furin future therapeutic Golgi complex host cell Human human monoclonal antibodies Human monoclonal antibody immunofluorescence microscopy immunological indicated infected cells infected with SARS-CoV-2 Infection Interaction isolate isolates Microscopy mitigate MONITOR monoclonal new virus occur offer Protein provided RBD reagent Receptor binding domain receptor binding domain (RBD) recognize required S protein S protein cleavage S protein RBD SARS- CoV-2 SARS-CoV-2 SARS-CoV-2 clinical isolates SARS-CoV-2 spike SARS-CoV-2-infected cell SARS-CoV-2-infected cells Singapore Specific spike staining the RBD the S protein therapeutic These data Transmission Vaccine variant virus infection virus particles virus-infected cell virus-infected cells was used were used while
[DOI] 10.1128/jvi.00455-22 PMC 바로가기 [Article Type] Article

Immune features of COVID-19 convalescent individuals revealed by a single-cell RNA sequencing

단일 세포 RNA 시퀀싱으로 밝혀진 COVID-19 회복기 개인의 면역 기능

Article

Published on 2022-07-012022-09-11
Journal: International immunopharmacology [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단,

[키워드] Activation addition B cell B cell subset B cells Bioinformatics analysis biological processe biological processes CD4 CD8 Cell cell receptor cell-cell adhesion clonal expansions Cluster convalescence convalescent convalescent COVID-19 patient convalescent COVID-19 patients convalescent individual convalescent individuals convalescent patient Convalescent patients COVID-19 Critical declined decreased expression differentiation downregulation effector memory feature function functions GNLY HLA class I HLA class II HLA class II genes humoral immune response Humoral immunity immune protection immune response immune responses increased expression infections Innate innate immune responses Innate immunity Interferon-gamma involved leukocyte mapped marginal zone mechanism Migration moderate natural infection neutrophil Peripheral blood peripheral blood samples phenotypic reflected Regulation Reinfection retained RNA SARS-CoV-2 SARS-CoV-2-specific immune response SARS-CoV-2-specific immune responses severe cases single cell RNA sequencing Single-cell RNA sequencing subjects subset sustained T cell T cell activation T cell response T/B cell receptor repertoire. TCR upregulation was increased weakened with COVID-19 zone
[DOI] 10.1016/j.intimp.2022.108767 PMC 바로가기 [Article Type] Article

COVID-19: Omicron – the latest, the least virulent, but probably not the last variant of concern of SARS-CoV-2

COVID-19: 오미크론 - 최신, 가장 덜 독성이지만 SARS-CoV-2의 우려의 마지막 변종은 아닐 것입니다.

Review

Published on 2022-07-012022-09-11
Journal: Microbial Biotechnology [Category] COVID19(2023년), SARS, 변종,

[키워드] affected Antibody Response Antiviral booster breadth cell entry Cellular immune response convalescent patient Convalescent patients COVID-19 pandemic Delta demonstrated dominant Endocytic pathway experiment explain fusion hamsters Immune escape immunization Infection intrinsic less Lineage Lung function mainstream mice monoclonal antibodies mutated Mutation neutralization omicron Omicron variant plasma membrane population immunity preserved question raising Replication respiratory tract SARS-CoV-2 SARS-CoV-2 strain serum antibodies serum antibody Severe infection severe infections South Africa Spike protein the spike protein therapeutic titre trajectory Transmission vaccinee vaccinees variant virulence virulent VoC widespread
[DOI] 10.1111/1751-7915.14064 PMC 바로가기 [Article Type] Review

Functional Profiling of In Vitro Reactivated Memory B Cells Following Natural SARS-CoV-2 Infection and Gam-COVID-Vac Vaccination

자연 SARS-CoV-2 감염 및 Gam-COVID-Vac 백신 접종 후 시험관 내 재활성화된 기억 B 세포의 기능 프로파일링

Article

Published on 2022-06-212022-09-11
Journal: Cells [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] Adenovirus antibody antibody-secreting cells B-cell response circulating comprehensive analysis convalescent patient Convalescent patients COVID-19 COVID-19 convalescent patient COVID-19 convalescent patients demonstrated elicit frequencies Frequency Gam-COVID-Vac Gam-COVID-Vac vaccine healthcare humoral Humoral immunity immune response immune responses Immunity individual Infection MBC MBCs memory B memory B cell memory B cells natural natural immunity Neutralizing Neutralizing antibodies outperform performed platform Profiling Receptor binding domain recipients robust SARS-CoV-2 SARS-COV-2 infection Serum level serum levels side significantly higher Sputnik V vaccine vaccination variants of SARS-CoV-2 Viral viral antigens virus-neutralizing virus-neutralizing antibodies
[DOI] 10.3390/cells11131991 PMC 바로가기 [Article Type] Article

Developing Pseudovirus-Based Neutralization Assay against Omicron-Included SARS-CoV-2 Variants

오미크론 포함 SARS-CoV-2 변이체에 대한 의사 바이러스 기반 중화 분석 개발

Article

Published on 2022-06-182022-09-11
Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] Alpha antibodies approved backbone Beta biosafety BSL-2 candidate collection time conditions conducted convalescent Convalescent patients convalescent plasma COVID-19 convalescent patient COVID-19 pandemic Developing drugs effective Efficiency expression plasmid full-length Gamma Genome Health HIV HIV-1 immune evasion in vitro luciferase reporter gene monoclonal antibodies neutralization Neutralization assay Neutralizing antibodies neutralizing capacity omicron parameter Particles Plasmid Prevention and control Protein pseudovirus Pseudovirus neutralization assay pseudoviruses reduced REGN10933 REGN10987 reporter gene S protein expression plasmids S309 SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Spread the S protein therapeutic Vaccine Vaccines variant was tested Wuhan
[DOI] 10.3390/v14061332 PMC 바로가기 [Article Type] Article

Effect of internet-delivered cognitive behavioral therapy on insomnia in convalescent patients with COVID-19: Protocol for a systematic review and meta-analysis

인터넷 제공 인지 행동 치료가 코로나19 회복기 환자의 불면증에 미치는 영향: 체계적인 검토 및 메타 분석을 위한 프로토콜

Article

Published on 2022-06-142022-09-11
Journal: PLoS ONE [Category] MERS, meta-analysis,

[키워드] 95% CI addition addressed behavioral therapy cause CBM Chinese Chinese Biomedical Literature Database clinical CNKI Cochrane Library cognitive cognitive behavioral therapy conducted continuous variable continuous variables convalescence convalescent patient Convalescent patients coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Data analysis Effect epidemicity evaluate the effect evaluated Evidence Grey literature Guidance heterogeneity IMPROVE inception indicated information Infrastructure Insomnia Intervention life literature mean difference Meta-analysis meta-analysis and systematic review positive Previous studies Prospective PROSPERO public health threat Quality of life recent reduce Registered registration number researcher review searched standardized mean difference Stata software systematic review systematic reviews therapy Treatment Trial used to calculate Version Web of Science with COVID-19
[DOI] 10.1371/journal.pone.0269882 PMC 바로가기 [Article Type] Article

Egg-Derived Anti-SARS-CoV-2 Immunoglobulin Y (IgY) With Broad Variant Activity as Intranasal Prophylaxis Against COVID-19

COVID-19에 대한 비강내 예방으로서 광범위한 변이 활성을 갖는 계란 유래 항-SARS-CoV-2 면역글로불린 Y(IgY)

Clinical Trial

Published on 2022-06-012022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단,

[키워드] 2019 novel coronavirus 2019-nCoV activity Administered Against Alpha anti-SARS-CoV-2 Antiviral approval approvals B.1.1.529 B.1.1.7 B.1.351 B.1.617.2 Beta binding capture chicken immunoglobulin clinical clinical trial clinical trial body Clinical use contagiousness Convalescent patients COVID-19 cross-reactivity Delta demonstrated develop Diseases distribution double-blind effective Emergency use authorization enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay Evidence evidence of greater healthy human tissue human tissues IgY Immunity immunized Immunoglobulin immunoglobulin Y index Infectious diseases intranasal intranasally multiple dose multiple doses nasal drop nasal drops nasal mucosa neutralization titer no evidence of Novel coronavirus omicron Phase 1 phase 1 study Placebo placebo-controlled Prevalence Prophylaxis raised Randomized RATs RBD Receptor-binding domain reduce reduced risk Safe safety profile SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 strain SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 viral sensitivity sera Spike protein the receptor-binding domain the SARS-CoV-2 Tolerability Transmission Trial Vaccine Vaccine hesitancy variants variants of concern variety Viral virus
[DOI] 10.3389/fimmu.2022.899617 PMC 바로가기 [Article Type] Clinical Trial

Implication of the emergence of the delta (B.1.617.2) variants on vaccine effectiveness

백신 효과에 대한 델타(B.1.617.2) 변이체의 출현의 의미

Review

Published on 2022-06-012022-09-11
Journal: Infection [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] Administered analyzed article assist AstraZeneca B.1.617.2 breakthrough infections concern convalescent patient Convalescent patients COVID-19 COVID-19 vaccine COVID-19 vaccines death Delta delta variant Delta variants determine disease severity effective Effectiveness Efficacy FIVE Hospitalization in vitro in vivo incidence infection with SARS-CoV-2 Meta-analysis Moderna neutralization neutralizing antibody Oxford-AstraZeneca pandemic Pfizer Pfizer-BioNTech reduced reducing reductions in SARS-CoV-2 SARS-CoV-2 pandemic screened searched second dose significant reductions significantly symptomatic infection Transmission vaccinated individual vaccinated individuals vaccination Vaccinations Vaccine Vaccines variant variants
[DOI] 10.1007/s15010-022-01759-1 PMC 바로가기 [Article Type] Review