Indicators of recent COVID-19 infection status: findings from a large occupational cohort of staff and postgraduate research students from a UK university최근 COVID-19 감염 상태의 지표: 영국 대학의 직원 및 대학원 연구원으로 구성된 대규모 직업 집단의 결과Article Published on 2022-08-092022-09-11 Journal: BMC Public Health [Category] SARS, 치료기술, [키워드] Algorithm antibodies antibody Antibody detection Antibody test antibody test result Antibody testing antibody tests assist classification Cohort Cohort studies cohort study Concordance contribute core COVID-19 COVID-19 case COVID-19 cases COVID-19 illness COVID-19 infection COVID-19 serological testing criteria definitive diagnosis described Descriptive statistics difference evaluate Evidence FIVE followed by Health Indicator Interpretation lateral flow likelihood London meeting overlap participant Participants positive positive result positive symptom predicted Prevalence proportion Public public health report reported Research serological Serological testing significantly Support suspicion Symptom Symptoms test cassette test result to define vaccination [DOI] 10.1186/s12889-022-13889-0 PMC 바로가기 [Article Type] Article
Drug repurposing: a systematic review on root causes, barriers and facilitators약물 용도 : 근본 원인, 장벽 및 촉진자에 대한 체계적인 검토Article Published on 2022-07-292022-08-31 Journal: BMC health services research [Category] 신약개발, [키워드] Analysis approach article articles business causes Characteristics Cochrane Library Collection complex Compound consolidation core database disease drug Drug abandonment Drug development Efficacy eligible Emergency use authorization example facilitate facilitator facilitators focus food Food and Drug Administration Google Scholar Inadequate include information intellectual property knowledge lack Modification MOST open Open Science Framework outcome OVID problem PROSPERO protocol receiving Registered Registration Regulatory Repurposed drug repurposing Research Research design resource risk screened Source Support systematic review Therapies therapy Transparency treat Trial Web of Science [DOI] 10.1186/s12913-022-08272-z PMC 바로가기 [Article Type] Article
Drug-Target Network Study Reveals the Core Target-Protein Interactions of Various COVID-19 TreatmentsArticle Published on 2022-07-062022-10-04 Journal: Genes [Category] COVID19(2023년), SARS, 신약개발, [키워드] Analysis Bronchoalveolar lavage fluid cascade caused Cell cell membrane conducted core coronavirus disease COVID-19 COVID-19 symptom CTD curated database death rate Diseases downstream cellular signaling drug Drug discovery drug treatment drug-target drug-target network drugs effort function Genes Human interconnected genes involved knowledge lung Macrophage medications mitigate network Numerous overlapped overlapping pandemic pharmacological target PPI protein-protein interaction receptors reduce risk SARS-CoV-2 virus severe COVID-19 significantly single-cell Symptom T cell target gene text mining [DOI] 10.3390/genes13071210 PMC 바로가기 [Article Type] Article
Severity of omicron variant of concern and effectiveness of vaccine boosters against symptomatic disease in Scotland (EAVE II): a national cohort study with nested test-negative design스코틀랜드의 증후성 질환에 대한 백신 부스터의 우려 및 효과에 대한 오미크론 변이의 심각도(EAVE II): 중첩 테스트 음성 디자인을 사용한 국가 코호트 연구Article Published on 2022-07-012022-09-11 Journal: The Lancet. Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI adjusted Admission booster booster dose Booster vaccine booster vaccines Care case-control study cohort analysis cohort study core COVID-19 defined Delta VOC dose dose of vaccination Edinburgh effective Effectiveness enhanced estimate Health Data Research UK Hospital admission hospitalisation individual individuals Infection initial Innovation laboratory data National offer omicron Omicron variant outcome platform positive positive RT-PCR proportion Public reduction in Reinfection risk risk of COVID-19 S-gene SARS-COV-2 infection Scottish severity Spread symptomatic symptomatic COVID-19 symptomatic disease symptomatic infection symptomatic SARS-CoV-2 infection tested the SARS-CoV-2 university vaccination Vaccine vaccine dose VoC with infection [DOI] 10.1016/S1473-3099(22)00141-4 PMC 바로가기 [Article Type] Article
Role of Fc Core Fucosylation in the Effector Function of IgG1 AntibodiesIgG1 항체의 이펙터 기능에서 Fc 코어 푸코실화의 역할Review Published on 2022-06-302022-09-12 Journal: Frontiers in Immunology [Category] MERS, 진단, [키워드] ADCC ADCP antibody Antigen approved B-cell Cancer Cell cellular cytotoxicity Clinical use core decrease Dengue disease severity Effect effector Efficacy ENhance fetal fucosylation function highlighting human IgG1 Fc humoral Humoral response IgG IgG Fc IgG1 IgG1 antibody immune in vitro in vivo Infection Inflammatory diseases knowledge less mAb mAbs Macrophage mechanism Modification monoclonal antibody N-glycan natural immune response natural killer NK cells parasites phagocytosis Platelet polyclonal polymorphonuclear neutrophil pregnant women Regulation reported role SARS-CoV 2 Seven shown significantly therapeutic therapeutic antibodies treat virus virus infection [DOI] 10.3389/fimmu.2022.929895 PMC 바로가기 [Article Type] Review
Adapting to the Era of Virtual Recruitment: Radiology Departmental Website Response to COVID-19 and Portrayal of the Resident ExperienceResearch article Published on 2022-05-012022-10-05 Journal: Academic radiology [Category] 진단, [키워드] ABR activity administration Analysis application change changes Community core COVID-19 COVID-19 pandemic criteria described diagnostic education ERAS evaluate evaluated excluded experience healthcare help Highlights IMPROVE indicated information less majority material Measures media medical student objective offered Program protocols radiology rationale recruitment resident resource response Result service sick vaccination website wellness [DOI] 10.1016/j.acra.2021.11.023 [Article Type] Research article
Developing a shared sepsis data infrastructure: a systematic review and concept map to FHIR Research Published on 2022-04-042022-10-05 Journal: NPJ Digital Medicine [Category] 바이오마커, [키워드] analyzed approach Awareness clinical care clinical variable clinical variables condition Consensus core COVID-19 criteria described develop Developing disease element English excluded extension flexible Health health system highlighting hospital identify IMPROVE interoperability lack manuscript mapped provided public health required Research resource Sepsis Septic shock spectrum of diseases subtype Subtypes systematic review to define unique variable yielding [DOI] 10.1038/s41746-022-00580-2 [Article Type] Research
Quality of Life in Patients with Pancreatic Cancer before and during the COVID-19 PandemicObservational Study Published on 2022-03-212022-10-05 Journal: International Journal of Environmental Research an [Category] 임상, [키워드] addressed adverse outcome Affect Anxiety applied arising benefit Cancer cancer patient Care change Chemotherapy clinical consequence Cohort concerning conducted core coronavirus disease 19 COVID-19 COVID-19 pandemic Deterioration distress emotional European Health healthcare heterogenous highlight homogenous impairing indicated Intervention life limitation medium Mental outcome pancreatic Pancreatic cancer pancreatic tumor pandemic Patient patients Patients with cancer personal health physical Prolonged psychological support Quality Quality of life questionnaire recent regimen Resilience score Stress surgical survivor Treatment underlying disease urgency were expressed Worry [DOI] 10.3390/ijerph19063731 PMC 바로가기 [Article Type] Observational Study
Real-Time Internet of Medical Things System for Detecting Blood Leakage during Hemodialysis Using a Novel Multiple Concentric Ring Sensor새로운 다중 동심 링 센서를 사용하여 혈액 투석 중 혈액 누출을 감지하는 실시간 의료 사물 인터넷 시스템Article Published on 2022-03-032022-09-10 Journal: Sensors (Basel, Switzerland) [Category] MERS, SARS, 치료기술, [키워드] Accuracy analyzed automatically Blood blood leakage detection Candidates changed clinical study core COVID-19 detect dialysis evaluated experiment feasibility healthcare Hemodialysis high risk hospital Internet Internet of Medical Things (IoMT) leakage life-threatening load medical staff MONITOR multi-bed monitoring system Multiple novel Patient patient safety platform prosthetic questionnaire recruited reduced Ring sensitivity sensor subject System Telemedicine threshold venous needle dislodgement Volume Worry [DOI] 10.3390/s22051988 PMC 바로가기 [Article Type] Article
Outcomes assessed in therapeutic randomized controlled trials in hospitalized patients with COVID-19: is the meta Core Outcome Set (meta-COS) adopted?COVID-19로 입원한 환자의 치료 무작위 대조 시험에서 평가된 결과: 메타 핵심 결과 세트(meta-COS)가 채택됩니까?Comment Published on 2022-03-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] 임상, [키워드] core hospitalized patient Randomized controlled trial therapeutic [DOI] 10.1016/j.cmi.2021.11.017 PMC 바로가기 [Article Type] Comment