Inflammasome activation in infected macrophages drives COVID-19 pathology
감염된 대식세포의 인플라마좀 활성화는 COVID-19 병리를 유발합니다
Article
[키워드] ACE2 receptors
activate
Activation
antibody
attenuate
blockade
blocking
cascade
CD16
characterized
contributing to
COVID-19
COVID-19 pathology
Critical
disease
downstream
host infection
Human immune system
human macrophage
humanized
hyperinflammatory state
IFN
IL-1
IL-18
immune
in vivo
Infection
Infectious virus
Inflammasome
inflammasome activation
inflammasomes
Inflammatory cytokine
inflammatory cytokine production
inflammatory macrophages
Inflammatory response
interferon
Lung inflammation
Lung pathology
Lungs
Macrophage
macrophages
NLRP3 inflammasome
overactive
pathology
pathway
Prevent
pyroptosis
Remdesivir
Replication
required
SARS-CoV-2
SARS-COV-2 infection
Stage
sustained
undergo
viral replication
Viral RNA
[DOI] 10.1038/s41586-022-04802-1 PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41586-022-04802-1 PMC 바로가기 [Article Type] Article