Automated Library Construction and Analysis for High-Throughput Nanopore Sequencing of SARS-CoV-2Article Published on 2022-09-012022-11-16 Journal: The journal of applied laboratory medicine [Category] SARS, 변종, [키워드] 96-well plate addition Amplicon Analysis analyzed ARTIC protocol automated clade construction correlation Coverage demonstrated Dilution fraction implementation IMPROVE Laboratory library median Mutation Oxford PCR Plate prevalent processed purified RNA Quality control quality score reduced Region reliability required rising robust SARS-CoV-2 SARS-CoV-2 sequencing sequence sequenced Sequencing strain Support threshold unique variant variants of concern [DOI] 10.1093/jalm/jfac054 PMC 바로가기
Comparison of commercial SARS-CoV-2 surrogate neutralization assays with a full virus endpoint dilution neutralization test in two different cohorts두 개의 다른 코호트에서 상용 SARS-CoV-2 대리 중화 분석과 전체 바이러스 종말점 희석 중화 테스트의 비교Article Published on 2022-09-012022-09-11 Journal: Journal of virological methods [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제, [키워드] ACE2 angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antibody Antibody titers biosafety level Cohort cohorts convalescent Convalescent SARS-CoV-2-infected individuals COVID COVID vaccinated individuals Cutoff detect Determination Dilution Endpoint Full virus neutralization test glycoprotein gold gold standard indicate infected individuals Infection Interaction labor labor-intensive level 3 neutralization Neutralization assay neutralization test neutralization tests Neutralizing antibodies neutralizing antibody Neutralizing antibody titer neutralizing antibody titers Qualitative quantitative measurement RBD Receptor binding domain receptor protein Replication SARS-CoV-2 SARS-CoV-2-infected individual spike glycoprotein surrogate surrogate virus neutralization test sVNT the RBD vaccinated individuals Viral viral spike virus Virus neutralization virus neutralization test VNT [DOI] 10.1016/j.jviromet.2022.114569 PMC 바로가기 [Article Type] Article
Ultrabright nanoparticle-labeled lateral flow immunoassay for detection of anti-SARS-CoV-2 neutralizing antibodies in human serumArticle Published on 2022-09-012022-11-15 Journal: Biomaterials [Category] SARS, 진단, 치료기술, [키워드] aggregation-induced emission anti-SARS-CoV-2 Antigen coated Concentration condition detect Dilution exhibited fluorescent human serum identify Lateral lateral flow immunoassay LFIA marker negative sample neutralizing antibody positive sample Precision protective immunity Protein rigidity SARS-CoV-2 semi-quantitative serum serum samples vaccinee was used [DOI] 10.1016/j.biomaterials.2022.121694 PMC 바로가기
Neutralizing Antibody Response to Pseudotype Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Differs Between mRNA-1273 and BNT162b2 Coronavirus Disease 2019 (COVID-19) Vaccines and by History of SARS-CoV-2 Infection유사형 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2)에 대한 중화 항체 반응은 mRNA-1273과 BNT162b2 코로나바이러스 질병 2019(COVID-19) 백신과 SARS-CoV-2 감염의 역사에 따라 다릅니다.Article Published on 2022-08-242022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, [키워드] 19 2 95% confidence interval Antibody titer BNT162b2 BNT162b2 vaccine calculated coronavirus 2 CoV COVID COVID-19 Dilution dose geometric mean GMT GMTs highest history increase Infection inhibitory linear mixed-effects models mRNA mRNA COVID-19 vaccine mRNA vaccine mRNA-1273 mRNA-1273 vaccine NAb Neutralizing antibodies neutralizing antibody participant participants with SARS-CoV-2 prospective cohort pseudotype virus receiving respiratory response SARS SARS-CoV-2 SARS-COV-2 infection sera single dose Symptoms T Test tested uninfected participant uninfected participants vaccination Vaccine vaccine dose was collected [DOI] 10.1093/cid/ciab1038 PMC 바로가기 [Article Type] Article
Neutralization titer biomarker for antibody-mediated prevention of HIV-1 acquisition Research Published on 2022-08-222022-10-05 Journal: Nature Medicine [Category] 변종, 비임상, 유전자 메커니즘, 임상, 진단, 치료기술, 치료제, [키워드] acquisition antibody average Biomarker circulating Concentration Dilution Efficacy Endpoint half-lives HIV-1 immunodeficiency in vitro Infection inhibitory Mediated neutralization potency neutralizing antibody predict predicted prevented prevention reduce regimen regimens required serum Serum Neutralization sustained Trial Vaccines virus viruses [DOI] 10.1038/s41591-022-01953-6 [Article Type] Research
Year-long wastewater monitoring for SARS-CoV-2 signals in combined and separate sanitary sewers결합 및 분리 위생 하수에서 SARS-CoV-2 신호에 대한 1년 동안의 폐수 모니터링Article Published on 2022-08-012022-09-11 Journal: Water environment research : a research publicatio [Category] SARS, 변종, [키워드] clinical testing combined sewer Concentration correlated correlation correlations COVID-19 cumulative data set data sets Dilution Epidemiology event explain Factor First wave Flow followed by observation observations occurred performed PMMoV Removing reported sampling SARS-CoV-2 SARS-CoV-2 gene SARS-CoV-2 genes Sewage surveillance sewer strength utility variant Wastewater-based epidemiology widespread [DOI] 10.1002/wer.10768 PMC 바로가기 [Article Type] Article
Comparison between five PCR techniques for the diagnosis of SARS-CoV-2SARS-CoV-2 진단을 위한 5가지 PCR 기술 비교Article Published on 2022-08-012022-09-11 Journal: Revista española de quimioterapia : publicación [Category] COVID19(2023년), SARS, 치료기술, [키워드] Becton Dickinson commercial kits concentrations Concordance determine Diagnosis diagnosis of SARS-CoV-2 diagnostic Dilution epidemiological FIVE Infection Negative predictive value negative sample NPV PCR pooling Positive predictive value positive sample PPV Predictive value real time Roche RT-PCR RT-PCR kit SARS-CoV-2 sensitivity serological Seven Specificities specificity were used [DOI] 10.37201/req/076.2020 PMC 바로가기 [Article Type] Article
Immunogenicity and Reactogenicity of Ad26.COV2.S in Korean Adults: A Prospective Cohort Study한국 성인에서 Ad26.COV2.S의 면역원성과 반응성: 전향적 코호트 연구Article Published on 2022-07-112022-09-11 Journal: Journal of Korean medical science [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Ad26 Ad26.COV2.S Adenovirus Adenovirus Vector Adverse adverse event adverse events AEs anti-S IgG Anti-spike baseline cellular immunity conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 decrease Delta Dilution enrolled enzyme enzyme-linked immunospot assay evaluated fatigue Fever followed by geometric mean geometric mean titers GMT GMTs GRADE Humoral immunity IgG antibody immunogenic immunogenicity injection site pain interferon interferon-γ Korean mononuclear cell MOST myalgia NAb titer Neutralizing Neutralizing activity neutralizing antibody responses omicron Omicron variant Omicron variants outcome pandemic participant Peripheral blood Prospective prospective cohort study resolved respiratory Safe SARS-CoV-2 serious AEs severe acute respiratory syndrome Coronavirus Single-dose South Korea T-cell immunity T-cell Response T-cell responses the median U/mL university hospital vaccination Vaccines variant variants Viral Viral variants waning immunity wild-type WT SARS-CoV-2 [DOI] 10.3346/jkms.2022.37.e210 PMC 바로가기 [Article Type] Article
Comparison of extraction-based and elution-based polymerase chain reaction testing, and automated and rapid antigen testing for the diagnosis of severe acute respiratory syndrome coronavirus 2중증급성호흡기증후군 코로나바이러스 2 진단을 위한 추출기반 및 용출기반 중합효소연쇄반응검사와 자동화 및 신속항원검사의 비교Article Published on 2022-07-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplification amplified Antigen antigen detection applied assays automated Chain Reaction clinical sample clinical samples Concentration coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Diagnosis diagnostic diagnostic test Dilution dilutions disease Elecsy Elecsys elution extraction Fuji Inc. Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples Novel coronavirus novel coronavirus disease novel coronavirus disease 2019 (COVID-19) Patient PCR PCR assay PCR test performed polymerase chain polymerase chain reaction positive Rapid diagnostic test RDT remained RNA RNA extraction Roche Diagnostics SARS-CoV SARS-CoV-2 SARS-CoV-2 antigen Science severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) System Takara Takara Bio virus [DOI] 10.1002/jmv.27709 PMC 바로가기 [Article Type] Article
Anti-SARS-CoV-2 activity of various PET-bottled Japanese green teas and tea compounds in vitro다양한 PET병 일본 녹차 및 차 화합물의 시험관 내 항 SARS-CoV-2 활성Article Published on 2022-07-012022-09-11 Journal: Archives of Virology [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antiviral activity antiviral therapeutics caused Compound compounds coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 treatment demonstrated Dilution dose-dependent manner Effectiveness EGCG Epicatechin epigallocatechin epigallocatechin gallate examined gallate global public health green green tea half-maximal inhibitory concentration half-maximal inhibitory concentrations in vitro inactivated Infection infectious titers inhibit SARS-CoV-2 inhibited investigated Japanese life cycle other compound other compounds outbreak polyethylene terephthalate Prophylaxis protease SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus shown Stage the SARS-CoV-2 treat Treatment Vaccine variety viral life cycle Viral RNA virucidal [DOI] 10.1007/s00705-022-05483-x PMC 바로가기 [Article Type] Article