Learning through a Pandemic: The Current State of Knowledge on COVID-19 and Cancer팬데믹을 통한 학습: COVID-19 및 암에 대한 지식 현황Review Published on 2022-02-012022-09-12 Journal: Cancer discovery [Category] Fulltext, MERS, 진단, [키워드] Analysis anticancer therapies Cancer Care consequence coronavirus disease COVID-19 COVID-19 pandemic current disparate Efficacy Evidence Health immune response implication learning offer pandemic Patient Patients with cancer provide risk factor severe disease state trajectory Treatment vaccination [DOI] 10.1158/2159-8290.CD-21-1368 PMC 바로가기 [Article Type] Review
Reliable and Scalable SARS-CoV-2 qPCR Testing at a High Sample Throughput: Lessons Learned from the Belgian InitiativeArticle Published on 2022-01-212022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] approach assays automated Belgium build components COVID-19 Data analysis disparate equipment force Government heterogeneous high-throughput testing Infection information initiative introduced lab automation lesson management manual intervention methodology molecular National pandemic platform Protective protocols qc monitoring qPCR Quality control reagents resources responsible robust Sample SARS-CoV-2 Standardization Testing the patient [DOI] 10.3390/life12020159 PMC 바로가기 [Article Type] Article
Single-dose SARS-CoV-2 vaccinations with either BNT162b2 or AZD1222 induce disparate Th1 responses and IgA productionBNT162B2 또는 AZD1222를 사용한 단일 용량 SARS-COV-2 백신 접종Research Article Published on 2022-01-192022-09-01 Journal: BMC Medicine [Category] SARS, 진단, [키워드] A significant reduction acute respiratory syndrome adaptive analyzed Anti-inflammatory antibody Antigen AZD1222 BNT162b2 change COVID-19 Cytotoxic T cells disparate dominant early immune response early immune responses Effectiveness effector T cell effector T cells elicited IgA IgG IgM and IgG Immune cell immune priming immune responses Impact induce isotype leukopenia priming respiratory Result SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 vaccination seronegative participant severe acute respiratory syndrome virus single dose Single-dose Spike protein Stimulation subpopulations supplementary material T cell T cell response T cells Th1 response type 1 helper Type 1 helper T cells vaccination Vaccine vaccinees virus while [DOI] 10.1186/s12916-022-02240-4 PMC 바로가기 [Article Type] Research Article
Strategies to minimize heterogeneity and optimize clinical trials in Acute Respiratory Distress Syndrome (ARDS): Insights from mathematical modelling급성 호흡 곤란 증후군(ARDS)에서 이질성을 최소화하고 임상 시험을 최적화하기 위한 전략: 수학적 모델링의 통찰력Article Published on 2022-01-012022-09-11 Journal: EBioMedicine [Category] 임상, [키워드] Action angiotensin approval baseline biologic Biomarker Biomarkers center Characteristics clinical response clinical responses clinical trial clinically Clustering complex interaction Corticosteroids COVID-19 Critical Critical care Critical illness Curie determined by Diabetic diabetic patients disease severity disparate driven by example expression foundation heterogeneity heterogeneity of treatment effect hyperinflamed hyperinflamed patient hyperinflamed patients identify IL6 immune response immunomodulation immunomodulatory Immunomodulatory therapies Immunosuppression individual Infection initiated Injury insight manuscript marker Mathematical modelling Microthrombosis Model modelling modulating neutrophil neutrophil recruitment NMF non-negative matrix factorization obese Older older patients outcome parameter Patient predict predicted Predictive Principal component principal component analysis RAS reduction Renin renin-angiotensin system representing Research respiratory respond responsible Strategy supported System System biology systemic cytokine Systems biology the disease therapy Treatment treatment initiation trials Trust [DOI] 10.1016/j.ebiom.2021.103809 PMC 바로가기 [Article Type] Article
Mediators of Racial Differences in COVID-19 Vaccine Acceptance and Uptake: A Cohort Study in Detroit, MIArticle Published on 2021-12-282022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acceptance African Americans Analysis Area black Community COVID COVID-19 COVID-19 vaccine Critical Detroit difference disparate effort eliminated Government groups Health Healthcare provider healthcare providers Hispanic IMPROVE Increased Intervention Local Mediation analysis mediation model mediator minority groups Mortality multivariable logistic regression Racial rates of infection reveal significantly Trust vaccination vaccination coverage Vaccine Vaccine hesitancy widespread with COVID-19 [DOI] 10.3390/vaccines10010036 PMC 바로가기 [Article Type] Article
Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formationArticle Published on 2021-12-142022-10-04 Journal: Nature Communications [Category] SARS, 변종, 유전자 메커니즘, [키워드] accumulated Alternative pathway analyzed Applying attenuate autophagy biogenesis Cell cellular chronic liver disease contribute COVID-19 different diseases disparate driving elevated fraction HCV hepatitis C virus highlighting host cell identify in viral involved Lipid mechanism membrane vesicle morphologically organelle pathway pharmacological phylogenetically proteomics purified recruited Replication responsible RNA virus RNA viruses SARS-CoV-2 SARS-CoV-2 replication therapy virus viruses [DOI] 10.1038/s41467-021-27511-1 PMC 바로가기 [Article Type] Article
Alzheimer disease in African American individuals: increased incidence or not enough data? Reviews Published on 2021-12-062022-10-05 Journal: Nature reviews. Neurology [Category] 바이오마커, 유전자 메커니즘, [키워드] African American Alzheimer disease Cognitive impairment cross-sectional Dementia Diagnostic Criteria disparate driver effective intervention evade highlight incidence increasingly individual individuals knowledge lack Racial recruitment substrate target the disease Treatment [DOI] 10.1038/s41582-021-00589-3 [Article Type] Reviews
Diverse integrated ecosystem approach overcomes pandemic-related fisheries monitoring challengesArticle Published on 2021-11-112022-10-29 Journal: Nature Communications [Category] Coronavirus, MERS, SARS, [키워드] approach assessment California Current caused collected COVID-19 COVID-19 pandemic disparate distribution ecosystem Ecosystem ecology effort Fisheries management observation overcome pandemic reduction resulting [DOI] 10.1038/s41467-021-26484-5 PMC 바로가기 [Article Type] Article
Assessment of mortality from COVID-19 in a multicultural multi-ethnic patient populationResearch Published on 2021-10-292022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] 95% CI age Asian assessment Characteristics Chi-square Clinical outcome Comorbidities Comorbidity conditions COVID-19 COVID-19 disease COVID-19 mortality COVID-19 patients disease disparate Ethnicity facilitator Gulf hospital hospitals hypertension increased mortality indicate Infectious disease information Kidney disease less Logistic regression management medical record middle Mortality most prevalent comorbidity Odds ratio offer Older age Patient patient age patient population patients Result significantly survival survival rate unique United Arab Emirates variables virus were used [DOI] 10.1186/s12879-021-06762-9 PMC 바로가기 [Article Type] Research
Mapping home internet activity during COVID-19 lockdown to identify occupation related inequalitiesArticle Published on 2021-10-262022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] accumulated adhere children Clustering conducted consequence contribute correlated COVID-19 COVID-19 pandemic demographic factor Diseases disparate employment Environmental social sciences Evidence Factor flexible help High-resolution Hypothesis identify Impact lockdown mapping proportion public health Risk factors secure Support virus spread [DOI] 10.1038/s41598-021-00553-7 PMC 바로가기 [Article Type] Article