Modulating the antibacterial effect of the existing antibiotics along with repurposing drug metformin기존 항생제의 항균 효과를 조절하고 약물 재사용인 메트포르민을 함께 활용하기Article Published on 2024-03-232024-08-22 Journal: Archives of Microbiology [Category] 세균성이질, [키워드] Drug repurposing haloperidol Hydroxychloroquine metformin molecular docking Molecular dynamics simulation Shigellosis
Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complexArticle Published on 2024-03-162024-09-05 Journal: Virus Research [Category] update2024, [키워드] Drug repurposing Helicase RNA-dependent RNA polymerase SARS-CoV-2 Screening [DOI] 10.1016/j.virusres.2024.199356 PMC 바로가기 [Article Type] Article
Drug Repurposing in the Chemotherapy of Infectious DiseasesReview Published on 2024-01-292024-09-05 Journal: Molecules [Category] update2024, [키워드] Chemotherapy drug repositioning Drug repurposing drug research and development drug target Infectious disease Neglected Tropical Disease [DOI] 10.3390/molecules29030635 PMC 바로가기 [Article Type] Review
Current trends and future prospects of drug repositioning in gastrointestinal oncologyPharmacology Review Published on 2024-01-042024-09-05 Journal: Frontiers in Pharmacology [Category] update2024, [키워드] colorectal cacner Drug repurposing gastrointestinal cancers Liver cancer Pancreatic cancer Therapeutic strategies [DOI] 10.3389/fphar.2023.1329244 PMC 바로가기 [Article Type] Pharmacology Review
Advances in Drug Discovery based on Genomics, Proteomics and Bioinformatics in Malariaarticle Published on 2023-12-312024-09-01 Journal: Current Topics in Medicinal Chemistry [Category] 말라리아, [키워드] artificial intelligence deep learning Drug development Drug discovery Drug repurposing FDA-approved drugs machine learning malaria Malaria elimination [Article Type] article
Signaling network analysis reveals fostamatinib as a potential drug to control platelet hyperactivation during SARS-CoV-2 infectionImmunology Original Research Published on 2023-12-212024-09-05 Journal: Frontiers in immunology [Category] update2024, [키워드] Controllability COVID-19 Drug repurposing fostamatinib Platelet SARS-CoV-2 signaling network [DOI] 10.3389/fimmu.2023.1285345 PMC 바로가기 [Article Type] Immunology Original Research
Repurposing Therapeutic Drugs Complexed to Vanadium in CancerReview Published on 2023-12-212024-09-05 Journal: Pharmaceuticals [Category] update2024, [키워드] cancer treatment decavanadate Drug repurposing vanadate vanadium complexes [DOI] 10.3390/ph17010012 PMC 바로가기 [Article Type] Review
Phenotypical Screening of an MMV Open Box Library and Identification of Compounds with Antiviral Activity against St. Louis Encephalitis VirusArticle Published on 2023-12-132024-08-29 Journal: Viruses [Category] 말라리아, [키워드] cationic amphiphilic compounds (CAD) cell culture-based screening Drug repurposing flavivirus St. Louis encephalitis virus
Anti- Toxoplasma gondii screening of MMV pandemic response box and evaluation of RWJ-67657 efficacy in chronically infected micearticle Published on 2023-11-302024-09-01 Journal: Parasitology [Category] 말라리아, [키워드] antitoxoplasmic compound bioinformatics Drug discovery Drug repurposing mice pandemic response box RWJ-67657 Screening Toxoplasma gondii toxoplasmosis [Article Type] article
The Functional Implications of Broad Spectrum Bioactive Compounds Targeting RNA-Dependent RNA Polymerase (RdRp) in the Context of the COVID-19 PandemicReview Published on 2023-11-252024-09-05 Journal: Viruses [Category] update2024, [키워드] Antiviral agents coronavirus RNA-dependent RNA Drug repurposing nsp12 protein polymerase RNA synthesis inhibitors SARS-CoV-2 scoping review [DOI] 10.3390/v15122316 PMC 바로가기 [Article Type] Review