Dynamic Alterations in the Respiratory Tract Microbiota of Patients with COVID-19 and its Association with Microbiota in the GutArticle Published on 2022-09-012022-11-15 Journal: Advanced Science [Category] 바이오마커, [키워드] Actinomyces alteration analyzed Bacteroide Biomarker Candida contributing to coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 progression determine Diagnosis disease Disease progression disease severity dynamic Enterococcus Fecal sample Gut gut microbiota ICU ICU Patients identify immune response Increases intensive care intensive care unit metagenome microbe microbial Microbiome microbiota mononuclear cell non-ICU pathway Patient patients patients with COVID-19 PBMC Peripheral blood positive correlation reduced respiratory respiratory microbiota. respiratory tract sequenced Significant significantly sputum Stage Streptococcus tract Treatment strategies with COVID-19 [DOI] 10.1002/advs.202200956 PMC 바로가기
An agent-based model to assess large-scale COVID-19 vaccination campaigns for the Italian territory: The case study of Lombardy region이탈리아 영토에 대한 대규모 COVID-19 예방 접종 캠페인을 평가하기 위한 에이전트 기반 모델: 롬바르디아 지역 사례 연구Article Published on 2022-09-012022-09-11 Journal: Computer methods and programs in biomedicine [Category] 변종, [키워드] administration age agency agent agent-based model analyzed approach assigned available dose available doses build calibrated case study concern Covasim COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines cumulative current death deaths Definition dose dynamic early stages Effectiveness Epidemiologic model Free greater group Health Health care Health care worker health care workers help individual individuals Infection infections Italian Italy knowledge lombardy mathematical methodological methodology National nuances parameter priority reduction in Support the vaccine vaccination Vaccine Vaccines variant variants variants of concern. [DOI] 10.1016/j.cmpb.2022.107029 PMC 바로가기 [Article Type] Article
Dynamic mechanisms of CRISPR interference by Escherichia coli CRISPR-Cas3 Research Published on 2022-08-302022-10-05 Journal: Nature Communications [Category] 변종, 유전자 메커니즘, 진단, [키워드] atomic binding cleavage Complete complex CRISPR Degradation degrade detect DNA DNA degradation double-stranded dsDNA dynamic elicit Escherichia coli exhibit Genome in vitro mechanism Microscopy multi non-specific NTS nucleic acid PAM Partial priming Protein R-loop recruited Release sequence single-stranded DNA spacer ssDNA Type type I [DOI] 10.1038/s41467-022-32618-0 [Article Type] Research
Heterogeneous responses in Google Trends measures of well-being to the COVID-19 dynamic quarantines in Chile Research Published on 2022-08-252022-10-05 Journal: Scientific Reports [Category] 치료법, [키워드] changes in Chilean coronavirus COVID-19 dynamic Effect Evidence facilitate Google health authorities heterogeneity induce lockdowns measure Psychological quarantine response Spread trend unique [DOI] 10.1038/s41598-022-18514-z [Article Type] Research
Viral Dynamic Surveillance in COVID-19 Patients: A Cohort StudyArticle Published on 2022-08-192022-11-15 Journal: BioMed Research International [Category] SARS, 변종, 치료기술, [키워드] 95% CI acute respiratory syndrome affected ALT Analysis AST caused CD4+ CD8+ coronavirus Coronavirus disease 2019 COVID-19 detectable dynamic feature index Infection median Patient Pneumonia polymerase chain retrospective reverse transcription risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2-infected patient Viral RNA virus was performed [DOI] 10.1155/2022/1399268 PMC 바로가기
Evaluating Effects of Dynamic Interventions to Control COVID-19 Pandemic: A Case Study of Guangdong, ChinaCOVID-19 전염병 통제를 위한 동적 개입의 효과 평가: 중국 광둥 사례 연구Article Published on 2022-08-162022-09-11 Journal: International Journal of Environmental Research an [Category] 변종, [키워드] Accuracy adaptive Algorithm applied chain China comparable Control COVID-19 COVID-19 epidemic COVID-19 transmission dynamic dynamic intervention Effect Effectiveness Efficiency efficiency evaluation Epidemic epidemiological evaluate Evaluating Guangdong Guangzhou iLSEIR-DRAM model inflection point Intervention Logistic logistic function Markov Markov chain optimization parameter Prevention and control promote Quantitative rejection SEIR Seven susceptible-exposed-infected-removed the epidemic transmission rate transmission rate. virus variants [DOI] 10.3390/ijerph191610154 PMC 바로가기 [Article Type] Article
Structural and Dynamic Insights into SARS-CoV-2 Spike-Protein-Montmorillonite InteractionsSARS-CoV-2 스파이크-단백질-몬모릴로나이트 상호작용에 대한 구조적 및 동적 통찰력Article Published on 2022-08-022022-09-11 Journal: Langmuir : the ACS journal of surfaces and colloid [Category] COVID19(2023년), SARS, 변종, [키워드] Cell cell entry Critical develop drug drug therapy dynamic effective electrostatic explicit glycan glycans help hydrophobic hydrophobic interaction hydrophobic interactions immune response insight Interaction interactions Ion mechanism Modification molecular dynamics Molecular dynamics simulation Montmorillonite nanoparticle pandemic performed probe Protein provide residue residues S protein SARS-CoV-2 therapeutic therapy Vaccine Vaccine development Vaccines variant virus world population [DOI] 10.1021/acs.langmuir.2c00837 PMC 바로가기 [Article Type] Article
Elucidation of correlation between SARS-CoV-2 RdRp and N gene cycle threshold (Ct) by RT-PCR with age and gender연령 및 성별에 따른 RT-PCR에 의한 SARS-CoV-2 RdRp와 N 유전자 주기 역치(Ct) 간의 상관관계 규명Article Published on 2022-08-012022-09-11 Journal: Clinica chimica acta; international journal of cli [Category] COVID19(2023년), SARS, 치료법, [키워드] Abu acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age age and gender Analysis association caused children conducted coronavirus coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 patients COVID19 Ct value Ct values cycle cycle threshold Diseases dynamic Factor female females Gender global public health global public health emergency implication in viral individual longitudinal longitudinal analysis male mutated N gene N genes no statistically significant difference outcome P-value prevalent ranged RdRP RdRp gene risk rRT-PCR rRT-PCR. RT-PCR SARS-CoV-2 SARS-CoV-2 RdRp second wave significantly higher statistically significant difference strain study period target threshold Viral load viral loads [DOI] 10.1016/j.cca.2022.06.008 PMC 바로가기 [Article Type] Article
Dynamic of a two-strain COVID-19 model with vaccinationResearch article Published on 2022-08-012022-10-05 Journal: Results in Physics [Category] 변종, [키워드] addition Affect analyzed approaches basic reproductive number Bifurcation calculate caused Characteristics Community condition COVID-19 COVID-19 transmission de novo dominant dynamic Dynamical systems Efficacy Endemic Immunity initial Lyapunov function mathematical mutations parameter provided Reproduction number Respiratory illness Result RNA shown Simulation stability stain strain Support the disease threshold Transmissibility Transmission Two-strain COVID-19 vaccination Vaccine variant virus [DOI] 10.1016/j.rinp.2022.105777 [Article Type] Research article
Urtica dioica Agglutinin: A plant protein candidate for inhibition of SARS-COV-2 receptor-binding domain for control of Covid19 InfectionUrtica dioica Agglutinin: Covid19 감염 통제를 위한 SARS-COV-2 수용체 결합 도메인 억제를 위한 식물성 단백질 후보Article Published on 2022-07-282022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, [키워드] ACE2 addition angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme-2 Antiviral effect average bind binding binding affinity binding energy binding free energy binding site calculated Cell complex convalescent serum coronavirus docked docking docking result docking results domain Donor donors dynamic effective effective drug effective drugs ELISA ELISA assay enzyme exhibited free energy Gromacs host cell human cells IgG Infection inhibit inhibitory activity Interaction limitation MD simulation mechanism Medicine Medicines MTT Mutation peptide Prevent Previous studies Protein RBD RBD binding RBD complex RBD protein Receptor-binding domain Result S-protein Safe SARS-CoV SARS-CoV-2 Simulation spike Spike protein spike protein of SARS-CoV-2 stability the cell the RBD Toxicity Urtica Vaccine virus was performed was used [DOI] 10.1371/journal.pone.0268156 PMC 바로가기 [Article Type] Article