estrogen receptor
[용어속성] Term
Examining the effector mechanisms of Xuebijing injection on COVID-19 based on network pharmacology
Research
[키워드] activated
Activation
Active ingredient
ALB
albumin
Analysis
Anti-inflammatory
AutoDock
B cell
binding activity
biological process
BPS
cascade
CASP3
cellular response
Chinese
component
Compound
coronavirus disease
Coronavirus disease 2019
COVID-19
COVID-19 disease
Cytoscape
Cytoscape software
database
demonstrated
disease
docking score
Effect
effective
Effector mechanism
Effects
EGFR
endothelial
enrichment analysis
epidermal
ESR1
estrogen receptor
Examining
explain
Extracellular
GAPDH
GeneCard
Genes
growth factor
IL-2
Inflammation
ingredient
injection
International
JUN
KEGG
Kyoto
less
MAPK
MAPK1
MAPK14
MAPK8
mechanism
Mild
molecular docking
Necrosis
network pharmacology
NF-κB
nuclear
Ontology
participated
Pathways
pharmacological mechanism
PI3K
potential mechanism
potential therapeutic target
PPI
predict
produced
Protein
protein-protein interaction
provided
PTGS2
RAS
receptor
regulated
Regulation
renin-angiotensin system
Result
searched
Sepsis
severe pneumonia
signaling pathway
STAT3
SwissTargetPrediction database
synergistic
T-cell receptor
target
targets
therapeutic effect
TLR
TNF
Toll-like receptor
Topology
Transcription
Treatment
TRP
VEGF
was used
Xuebijing
[DOI] 10.1186/s13040-020-00227-6 PMC 바로가기 [Article Type] Research
[DOI] 10.1186/s13040-020-00227-6 PMC 바로가기 [Article Type] Research
Identifying Pathways and Networks Associated With the SARS-CoV-2 Cell Receptor ACE2 Based on Gene Expression Profiles in Normal and SARS-CoV-2-Infected Human Tissues
Molecular Biosciences
[키워드] ACE2
ACE2 expression
angiotensin-converting enzyme 2
Cancer
Cell
Clinical outcome
correlation
ESR1
ESR2
estrogen receptor
exceeded
excessive immune response
expression
expression level
female
females
gene co-expression network
gene expression profile
Gene expression profiles
gene set enrichment analysis
growth
had no
healthy
host cell receptor
Human
human tissue
human tissues
identifying
immune
Immune cell
immune defense
Immune signatures
involved
male
males
mechanism
metabolism
network
normal
Numerous
other diseases
pathway
positive
profile
proliferation
receptor
robust
SARS-CoV-2
SARS-CoV-2 cell receptor
SARS-COV-2 infection
significant difference
significantly
susceptible
the SARS-CoV-2
tissue
tissues
upregulated
upregulation
[DOI] 10.3389/fmolb.2020.568954 PMC 바로가기 [Article Type] Molecular Biosciences
[DOI] 10.3389/fmolb.2020.568954 PMC 바로가기 [Article Type] Molecular Biosciences
Cellular and Molecular Pathways of COVID-19 and Potential Points of Therapeutic Intervention
Pharmacology
[키워드] ACE2
Alpha
alveolar cell
antagonists
Apoptosis
AT1
biological marker
blockade
blockers
capillary leakage
CDK9
Cell
cellular and molecular
chemotactic
clinical feature
clinical marker
contribute
COVID-19
COVID-19 immune response
CRP
cytokine release
Cytokine storm
Cytokines
cytoplasmic
Defense
Degradation
Dexamethasone
differentiation
Diffuse alveolar damage
downstream signaling pathway
doxycycline
element
elevated
elevated lactate dehydrogenase
entry of SARS-CoV-2
epithelial
estrogen receptor
expression
IL-17
IL-6
immune
immune response
Immunity
include
infiltration
Inflammatory
Inflammatory cytokine
inflammatory cytokine production
inflammatory signaling
inhibitor
initial
Injury
interferon response
Intervention
Ivermectin
Jak
kinase inhibitors
LDH
lung tissue
MAPK
mechanism
melatonin
membrane fusion
membrane-bound
molecular
monocyte
monocyte-derived macrophage
NETosis
NETs
neutrophil
Neutrophil extracellular trap
Neutrophil-to-lymphocyte ratio
NF-κB
NLR
p65
pathogenic
pathophysiology
pathway
Platelet
Pneumocytes
Point
Potential
pro-inflammatory
promote
Prophylaxis
provoke
receptor
reduce
Remdesivir
Research
respiratory epithelia
respiratory epithelial cells
SARS-CoV-2 coronavirus
selective
Signal transduction
skewed
subtype
T-cell
therapeutic interventions
therapeutic response
Therapeutics
thrombosis
TNF-α
type I interferons
type III
Vascular
Viral load
virus
[DOI] 10.3389/fphar.2020.01169 PMC 바로가기 [Article Type] Pharmacology
[DOI] 10.3389/fphar.2020.01169 PMC 바로가기 [Article Type] Pharmacology
Selective Estrogen Receptor Modulators in COVID-19: A Possible Therapeutic Option?
Pharmacology
[키워드] Antiviral
COVID-19
Cytokine storm
Estrogen
estrogen receptor
modulator
SARS-CoV-2
Selective estrogen receptor modulators
[DOI] 10.3389/fphar.2020.01085 PMC 바로가기 [Article Type] Pharmacology
[DOI] 10.3389/fphar.2020.01085 PMC 바로가기 [Article Type] Pharmacology