Delayed respiratory syncytial virus outbreak in 2020 in Taiwan was correlated with two novel RSV-A genotype ON1 variants2020년 대만에서 지연된 호흡기 세포융합 바이러스 발병은 2개의 새로운 RSV-A 유전자형 ON1 변이체와 상관관계가 있었습니다Article Published on 2022-05-012022-09-11 Journal: Influenza and Other Respiratory Viruses [Category] MERS, 변종, 진단, [키워드] Affect Amino acid amino acid substitution Analysis analyzed association caused children Clinical characteristics Clinical data Cluster conducted correlated COVID-19 mitigation measures Delayed demonstrated determine disease Epidemiology exploration Factor G protein Genotype greater Hospital admission Hospitalized Human Human respiratory syncytial virus Infant Infants Infection Molecular epidemiology MOST nasopharyngeal sample Nasopharyngeal samples need for oxygen outbreak oxygen pathogen Patient patient data performed Phylogenetic analysis positive profile proportion recorded respiratory respiratory syncytial virus respiratory tract RSV sequenced steroid steroid therapy strain Taiwan therapy variant variants Viral [DOI] 10.1111/irv.12951 PMC 바로가기 [Article Type] Article
A Faster, Novel Technique to Detect COVID-19 Neutralizing AntibodiesCOVID-19 중화 항체를 탐지하는 더 빠르고 새로운 기술Article Published on 2022-03-272022-09-11 Journal: Medical science monitor : international medical jo [Category] MERS, SARS, 진단, 치료기술, [키워드] Analysis antibody AZ vaccine collected correlation COVID-19 COVID-19 pandemic criterion Data analysis dataset demonstrated detect develop Efficacy Efficiency ELISA ELISA assay exploration faster first and second dose Healgen indicated lateral flow immunoassay leads LFIA test NAb Neutralizing antibodies neutralizing antibody novel participant Participants Pearson platform predict promoted Research second dose sera specimen spectrometer Spread technique Vaccine vaccine efficacy vaccine trial [DOI] 10.12659/MSM.935812 PMC 바로가기 [Article Type] Article
Exploration of the ocular surface infection by SARS-CoV-2 and implications for corneal donation: An ex vivo studySARS-COV-2에 의한 안구 표면 감염의 탐색 및 각막 기증에 대한 시사점 : 생체 외 연구Research Article Published on 2022-03-012022-09-10 Journal: PLoS Medicine [Category] MERS, SARS, 치료기술, [키워드] 24 hour 24 hours ACE-2 acute respiratory syndrome aims Algorithms angiotensin angiotensin-converting enzyme 2 bulbar conjunctiva cathepsin cellular entry Conjunctiva Contamination contraindication contraindications Cornea Corneal Corneal Graft Corneal transplantation coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 crisis Ct value Culture culture media decrease diagnosed diagnosed with COVID-19 Donor Donor selection donors enzyme epithelial cell epithelial cells epithelium evaluate Evidence Ex vivo exacerbated exploration expresse expressed expression expression of SARS-CoV-2 expression pattern female genetic material healthy donor immunohistochemistry implication IMPROVE increase in Infection infectious dose inoculation involved lack limbus limited sample size mandatory media median moderate molecular mRNA level nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs Not contaminated Ocular surface organ organ culture pandemic pathway Patient PCR positive Positive test Postinfection promote promoted Protein qPCR quantified quantitative PCR question RdRP receptor Replication researcher respiratory respond retrieved reverse transcription Reverse transcription quantitative PCR risk risk of transmission RNA RNA copy RNA sequence RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 receptor SARS-CoV-2 receptors SARS-CoV-2 RNA SARS-CoV-2 viral SARS-CoV-2 virus Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significant increase Support TCID tested tissue tissue culture tissues TMPRSS2 Transmission utility Viral Viral detection Viral RNA was tested were infected worsened [DOI] 10.1371/journal.pmed.1003922 PMC 바로가기 [Article Type] Research Article
Predictive factors of insomnia during the COVID-19 pandemic in Bangladesh: a GIS-based nationwide distribution방글라데시 코로나19 팬데믹 기간 불면증 예측인자: GIS 기반 전국 분포Article Published on 2022-03-012022-09-11 Journal: Sleep medicine [Category] 치료제, [키워드] adverse outcome Analysis approach Bangladesh Comorbidities conducted country COVID-19 COVID-19 pandemic COVID-19 psychological impact cross-sectional cross-sectional study daytime demographics determinants distribution exhibit exploration Factor fear Fear of COVID-19 female gender form General population Geographic Geographic information system GIS-Based nationwide study heterogeneity identify implementation Information System Insomnia investigated knowledge measure media Mental moderate multifactorial pandemic participant Predictive presence of comorbidities Prevalence prevalent problems Psychological psychological Impact questionnaire reported risk factor significantly Sleep sleep problems sleep quality social media susceptibility Symptom System targeting Variability Variation [DOI] 10.1016/j.sleep.2021.04.025 PMC 바로가기 [Article Type] Article
An Exploration of Nutritional Education within the Holiday Activities and Food Programme in EnglandArticle Published on 2022-02-192022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] activity Analysis authority club Community conducted COVID Department for Education dietary intake education England ENhance example exploration facilitators food food insecurity food literacy Guidance HAF holiday activities and food holiday hunger holiday programme Impact impacts implementation IMPROVE include Inclusion involved knowledge mandatory mechanism nutritional education provide recruit required Research School School holidays suggested variety was used [DOI] 10.3390/ijerph19042398 PMC 바로가기 [Article Type] Article
Exploration of the Mechanism of Lianhua Qingwen in Treating Influenza Virus Pneumonia and New Coronavirus Pneumonia with the Concept of “Different Diseases with the Same Treatment” Based on Network PharmacologyResearch Article Published on 2022-02-082022-10-31 Journal: Evidence-based Complementary and Alternative Medicine : eCAM [Category] COVID-19, [키워드] 3CL ACE2 angiotensin-converting enzyme 2 Apoptosis binding biological process biological processes cell proliferation component components concept COX2 cytokine Cytoscape database DAVID docking docking result emodin enrichment analysis exploration FIVE IL-17 IL-6 immune system Influenza virus interleukin-6 Intervention Invasion involved KEGG Kyoto Luteolin MAPK mechanism metabolism Necrosis network New Novel coronavirus Occurrence Ontology pathway Pathway enrichment analysis Pathways Pharmacology Pneumonia protease Protein quercetin Regulation Result rutin screened Seven T cell receptor target targets TNF Toll-like receptor treating Treatment was used [DOI] 10.1155/2022/5536266 PMC 바로가기 [Article Type] Research Article
Artificial intelligence in the prediction of protein–ligand interactions: recent advances and future directions단백질 - 리간드 상호 작용의 예측에서 인공 지능 : 최근 발전 및 미래 방향Review Published on 2022-01-272022-09-10 Journal: Briefings in Bioinformatics [Category] SARS, 치료제, [키워드] Algorithm approach approval artificial intelligence binding binding affinity binding pose binding site classical computational approach Computational approaches computational method conformation correlation COVID-19 pandemic database databases deep learning deep learning methods domain Drug discovery drugs exploration Interaction interactions Ligand ligands machine learning New predict Protein protein–ligand interaction targets unison [DOI] 10.1093/bib/bbab476 PMC 바로가기 [Article Type] Review
An Exploration of COVID-19 Impact and Vaccine Hesitancy in Parents of Pediatric Hematopoietic Stem Cell Transplant (HCT) Recipients Research Published on 2022-01-242022-10-05 Journal: Bone marrow transplantation [Category] COVID19(2023년), SARS, 임상, [키워드] age approval Cell children concern conducted COVID-19 COVID-19 vaccine Critical cross-sectional distress exploration exposure Facebook Factor family HCT hematopoietic Hesitancy Impact Improving information majority media National pandemic parent parental paucity of data pediatric recipient recipients recommendation recruited scale score Side effects Standard deviation STEM Transplant Vaccine VHS were used white [DOI] 10.1038/s41409-022-01587-9 [Article Type] Research
Protocol for SARS-CoV-2 post-vaccine surveillance study in Australian adults and children with cancer: an observational study of safety and serological and immunological response to SARS-CoV-2 vaccination (SerOzNET)SARS-COV-2 호주 성인 및 암 소아에서의 산후 감시 연구 프로토콜 : SARS-COV-2 백신 접종 (Seroznet)에 대한 안전 및 혈청 학적 및 면역 학적 반응에 대한 관찰 연구 (Seroznet)Study Protocol Published on 2022-01-202022-09-10 Journal: BMC Infectious Diseases [Category] SARS, 변종, 임상, [키워드] acceptability adverse event adverse events allergy Analysis Blood Cancer Cancer patients Characteristics Chemotherapy children clinical clinical trial clinical trials cohorts collected commenced comparable condition controls coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 vaccinations COVID-19 vaccine COVID-19 vaccines disease manifestation effective enrolled exploration FIVE haematological malignancy healthy healthy control healthy controls HM patient HM patients hypogammaglobulinaemia Immune checkpoint inhibitor Immune checkpoint inhibitors immune correlate immune correlates immune response Immunity Immunocompromise Immunological response Immunosuppression immunosuppressive condition immunosuppressive conditions incidence Infection less life malignancy morbidity and mortality naïve New observational study organ pandemic coronavirus Patient Patients with cancer peripheral Peripheral blood Polysorbate polysorbate 80 populations Post-vaccine pre-vaccination processed proportion prospective observational study Quality question receiving reducing Registered Registration registry reported required robust SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine Serologic response serologic responses serological serological response severe COVID-19 SOC solid organ supplementary material Surveillance systemic therapy T-cell therapy timepoint Toxicity Treatment Trial unique vaccination Vaccinations Vaccine Vaccine hesitancy vaccine response variants virus were excluded [DOI] 10.1186/s12879-021-07019-1 PMC 바로가기 [Article Type] Study Protocol
Family Caregivers’ Experiences and Coping Strategies in Managing Stroke Patients during the COVID-19 Pandemic: A Qualitative Exploration StudyArticle Published on 2022-01-142022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] analyzed burdens changed chronic disease Comprehensive conducted coping coping strategies Coping strategy Corona COVID-19 COVID-19 pandemic expected experience Experiences exploration family Family caregivers healthcare Healthcare system hospitals Impact Kelantan Malaysia management managing mechanism pandemic Participants Perspective positive public rehabilitation centers Purposive sampling Qualitative recorded recruited rehabilitation Strategy stroke supported survivor Survivors thematic analysis transcribed while worsening [DOI] 10.3390/ijerph19020942 PMC 바로가기 [Article Type] Article