Initial Insights Into the Genetic Epidemiology of SARS-CoV-2 Isolates From Kerala Suggest Local Spread From Limited IntroductionsGenetics Published on 2021-03-172022-10-31 Journal: Frontiers in Genetics [Category] COVID-19, [키워드] A2a clade Affect affecting amplicon-based sequencing Analysis China Coronavirus disease 2019 country COVID-19 COVID-19 case COVIDSeq COVIDSeq protocol Efficacy Epidemiology FIVE functional variant Genetic Genetic epidemiology haplotype analysis India individuals insight isolate Kerala knowledge Limited Local mapped outbreak Patient primer binding site rapid increase RT-PCR S gene SARS-CoV-2 sequenced single-nucleotide Spread variant variants virus [DOI] 10.3389/fgene.2021.630542 PMC 바로가기 [Article Type] Genetics
High throughput detection and genetic epidemiology of SARS-CoV-2 using COVIDSeq next-generation sequencingCOVIDSeq 차세대 시퀀싱을 사용한 SARS-CoV-2의 고처리량 검출 및 유전 역학Research Article Published on 2021-02-172022-08-13 Journal: PLoS ONE [Category] MERS, 변종, 유전자 메커니즘, 치료기술, [키워드] added affecting Analysis approach approaches B.1.112 B.1.99 best clades clinical sample Concordance coronavirus disease Coronavirus disease 2019 COVID-19 COVIDSeq COVIDSeq approach COVIDSeq protocol detect Diagnosis duplicate duplicates Epidemiology Evolution flow cell Genetic Genetic epidemiology global pandemic in-depth analysis Inconclusive India individual knowledge Lineage Multiplex-PCR Next-generation sequencing NovaSeq 6000 nucleotide positive RT-PCR SARS-CoV-2 sensitivity sequenced Sequencing sequencing approach Single nucleotide variant Surveillance the SARS-CoV-2 unique variant [DOI] 10.1371/journal.pone.0247115 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 genomic surveillance in Rondônia, Brazilian Western Amazon브라질 서부 아마존 론도니아에서 SARS-CoV-2 게놈 감시Article Published on 2021-02-122022-09-10 Journal: Scientific Reports [Category] MERS, 변종, 유전자 메커니즘, 치료기술, [키워드] alteration B.1 B.1.1 Brazil cancer patient Cancer patients Capital Computational biology and bioinformatics country COVID-19 detect dispersion District Diversity Effect epicenter Epidemic Epidemiology European event Evolution Federal District Genetic Genetic epidemiology highest incidence Infection information lineages Molecular biology MONITOR mortality rate Mutation mutations pandemic Replication respond RNA SARS-CoV-2 SARS-CoV-2 genomic surveillance Spread spread to state strain Strains Transmissibility [DOI] 10.1038/s41598-021-83203-2 PMC 바로가기 [Article Type] Article
Genomic epidemiology of a densely sampled COVID-19 outbreak in ChinaResearch Article Published on 2021-01-142022-10-28 Journal: Virus Evolution [Category] COVID-19, [키워드] Analysis basic reproduction number Bayesian center China Control COVID-19 outbreak data set diagnose dispersal effective Epidemic epidemiological epidemiological history Epidemiology estimate Genetic Genetic epidemiology Genome genomic highest Infection isolate modelling outbreak pandemic phylodynamic phylodynamics phylogenetics reported Reproduction number SARS- CoV-2 SARS-CoV-2 sequence structured coalescent the SARS-CoV-2 unlikely [DOI] 10.1093/ve/veaa102 PMC 바로가기 [Article Type] Research Article
Statistical power in COVID-19 case-control host genomic study designCOVID-19 사례 대조군 숙주 게놈 연구 설계의 통계적 힘Correspondence Published on 2020-12-282022-09-10 Journal: Genome Medicine [Category] MERS, SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] Accuracy Case-control COVID-19 detect disease severity disease severity of COVID-19 early stage early stages effect sizes Epidemiology estimate Factor feasibility Genetic Genetic epidemiology genetic factors genetic finding genetic findings Genetic studies Genetic variant Genetic variation Genome-wide association studies genomic Host Impact Infection Infectious disease information Interpretation moderate pandemic phenotypic data risk stratification SARS-CoV-2 SARS-COV-2 infection severity significantly Simulation Statistical genetics Study design supplementary material susceptibility therapeutic Treatment Vaccine development [DOI] 10.1186/s13073-020-00818-2 PMC 바로가기 [Article Type] Correspondence
SARS-CoV-2 lineage B.6 was the major contributor to early pandemic transmission in MalaysiaSARS-CoV-2 계통 B.6은 말레이시아에서 초기 전염병 전파의 주요 기여자였습니다.Research Article Published on 2020-11-302022-08-13 Journal: PLoS Neglected Tropical Diseases [Category] SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] Accuracy analysed Asia Asia-Pacific Asian B.1 B.1.1 B.6 can be used cause clinical community transmission confirmed case contributed correlated country COVID-19 COVID-19 case COVID-19 cases COVID-19 pandemic diagnostic diagnostic test Direct epidemiological link Epidemiology Genetic Genetic epidemiology genome sequence Genome sequence data Genome sequences genomic GISAID database identify increase Increases increases in India Lineage Local Malaysia mass molecular assays Molecular epidemiology MONITOR Mutation Nsp3 onward transmission over pandemic participant Patient performed phylogenetic analyses Phylogenetic analysis predominant Prevention and control provide real-time PCR assay reduced Registration reported SARS-CoV-2 SARS-CoV-2 lineage SARS-CoV-2 transmission second wave sensitivity sequence spike spikes Spread spread of COVID-19 strain subsequent Surveillance Transmission Travel virus virus spread viruses whole genome whole genome sequence [DOI] 10.1371/journal.pntd.0008744 PMC 바로가기 [Article Type] Research Article
ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study1001 Published on 2020-11-182022-10-28 Journal: Royal Society Open Science [Category] COVID-19, [키워드] ACE ACE inhibitors ACE2 ACE2 expression ACE2 gene acute respiratory syndrome Affect Angiotensin-converting enzyme angiotensin-converting enzyme inhibitors association cardiometabolic risk factor Cardiometabolic risk factors cardiometabolic trait cardiovascular risk factor cell entry circulating coronavirus coronavirus disease COVID-19 Effect enzyme eQTL Evidence expression Gene Expression Genetic Genetic epidemiology Genetic variant implicated implication inhibitor lung lung epithelium mendelian randomization outcome outcomes plasma positive predicted replicate responsible risk SARS-CoV-2 SARS-COV-2 infection serine protease TMPRSS2 serum severity of COVID-19 Support TMPRSS2 TMPRSS2 expression type 2 diabete virus [DOI] 10.1098/rsos.200958 PMC 바로가기 [Article Type] 1001
Solar Ultraviolet Radiation and Vitamin D Deficiency on Epstein-Barr Virus Reactivation: Observational and Genetic Evidence From a Nasopharyngeal Carcinoma-Endemic PopulationMajor Article Published on 2020-10-122024-09-04 Journal: Open Forum Infectious Diseases [Category] 대상포진, [키워드] Epstein-Barr virus Genetic epidemiology Nasopharyngeal carcinoma Ultraviolet radiation Vitamin D [DOI] 10.1093/ofid/ofaa426 PMC 바로가기 [Article Type] Major Article
Using parasite genetic and human mobility data to infer local and cross-border malaria connectivity in Southern Africa기생충 유전자 및 인간 이동성 데이터를 사용하여 남부 아프리카의 지역 및 국경 간 말라리아 연결성을 추론하기Article Published on 2019-04-022024-08-11 Journal: eLife [Category] 말라리아, [키워드] Genetic epidemiology malaria Mobility P. falciparum Parasite genomics [DOI] 10.7554/eLife.43510 PMC 바로가기
Echinococcosis: Advances in the 21st CenturyReview Published on 2019-02-132023-06-14 Journal: Clinical microbiology reviews [Category] Fulltext, 조류인플루엔자, [키워드] Alveolar echinococcosis Cystic echinococcosis Echinococcosis Echinococcus Echinococcus granulosus Echinococcus multilocularis Genetic epidemiology Genome strains/genotypes Transcriptome zoonosis [DOI] 10.1128/CMR.00075-18 PMC 바로가기 [Article Type] Review