Evaluation of the Post-COVID-19 Functional Status (PCFS) Scale in a cohort of patients recovering from hypoxemic SARS-CoV-2 pneumonia저산소증 SARS-CoV-2 폐렴에서 회복 중인 환자 코호트에서 코로나19 이후 기능 상태(PCFS) 척도 평가Article Published on 2022-03-012022-09-11 Journal: BMJ Open Respiratory Research [Category] SARS, 치료기술, [키워드] absence Borg Cohort cohort of patient cohort of patients correlation COVID-19 COVID-19 pneumonia CT scans detect Dyspnoea evaluate evaluated Follow-up functional Functional status high correlation hospitalisation hypoxemic life limitation Medical Research Council multisystemic Patient Pneumonia Pulmonary function test Pulmonary function tests Quality of life questionnaire Questionnaires respiratory infection SARS-CoV-2 pneumonia scale Screen Symptom symptomatic patient Symptoms Test viral infection [DOI] 10.1136/bmjresp-2021-001136 PMC 바로가기 [Article Type] Article
Performance evaluation of an automatic chemiluminescence immune platform for SARS-CoV-2 neutralizing antibody after vaccination in real worldSARS-COV-2를위한 자동 화학 발광 면역 플랫폼의 성능 평가 현실에서 예방 접종 후 항체Research Published on 2022-02-152022-09-01 Journal: BMC Infectious Diseases [Category] COVID19(2023년), Fulltext, MERS, SARS, 진단, [키워드] Adolescent BBIBP-CorV changes in Characteristics chemiluminescence China CLIA Cohort CoronaVac doses evaluated exceeded Follow-up followed by Hemolysis high correlation icterus immune immunity after vaccination immunoassays inactive injection inoculation investigated less linearity lipemia measure Neutralizing activity Neutralizing antibodies neutralizing antibody objective occurred performance Physical examination Plaque reduction neutralization test platform predominant PRNT Real world recipient recruited repeatability Result robust SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody SARS-CoV-2 vaccine schedule Sensitivity and specificity Serological assay serological assays seropositive Shenzhen significantly lower Sinovac strength Trial vaccination Vaccination Status Vaccinations Vaccine Variation volunteers [DOI] 10.1186/s12879-022-07141-8 PMC 바로가기 [Article Type] Research
A Lateral Flow Immunoassay Coupled with a Spectrum-Based Reader for SARS-CoV-2 Neutralizing Antibody DetectionArticle Published on 2022-02-102022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Accuracy acute respiratory syndrome addition approach approaches AstraZeneca caused collected coronavirus coronavirus disease Coronavirus disease 2019 (COVID-19) COVID-19 antibody COVID-19-related death demonstrated detect detection detection rate diagnoses diagnosing Diagnosis diagnostic effective enzyme-linked immunosorbent exhibited feasible Flow high correlation High-resolution Infection Lateral lateral flow immunoassay limitation mild case Negative predictive value neutralizing antibody Patient patients plasma sample polymerase chain Positive predictive value protocols ROC Curve SARS-CoV-2 SARS-COV-2 infection sensitivity Serological assay serum sample Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) severe cases shown specificity Stage tested the disease [DOI] 10.3390/vaccines10020271 PMC 바로가기 [Article Type] Article
Testing fractional doses of COVID-19 vaccines415 Published on 2022-02-072022-10-29 Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] accelerate approach approaches benefit booster Clinical data clinical evidence collected country COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines death deaths dosage dose dose stretching doses effective Effectiveness Efficacy epidemiological Evidence expected faster fractional dosing generate Government Health high correlation Infection less lower dose much lower Neutralizing antibody response Observational data occur pandemic potential benefit public health reduce researcher severe disease Significance Support switching Testing vaccination Vaccine Vaccines while [DOI] 10.1073/pnas.2116932119 PMC 바로가기 [Article Type] 415
Differential Dynamics of SARS-CoV-2 Binding and Functional Antibodies upon BNT162b2 Vaccine: A 6-Month Follow-UpBNT162B2 백신에 대한 SARS-COV-2 결합 및 기능적 항체의 차등 역학 : 6 개월 추적 관찰Article Published on 2022-02-022022-09-01 Journal: Viruses [Category] COVID19(2023년), Fulltext, MERS, SARS, 진단, [키워드] anti-RBD Anti-RBD IgG anti-Spike IgG antibody association binding BNT162b2 characteristic collected comparable correlates of protection COVID-19 cutoff point decrease Definition demonstrated dose Dynamics functional high correlation Humoral response IgG indications Laboratory laboratory procedures lack less maturation mRNA NAb NAbs Neutralizing antibodies neutralizing antibody of BNT162b2 receiver operating characteristic receiver operating characteristic curve receiving resulting SARS-CoV-2 serum sample serum samples vaccination were measured WHO [DOI] 10.3390/v14020312 PMC 바로가기 [Article Type] Article
A fast and cheap in-house magnetic bead RNA extraction method for COVID-19 diagnosis코로나19 진단을 위한 빠르고 저렴한 자체 자기 비드 RNA 추출 방법Article Published on 2022-02-012022-09-11 Journal: Journal of virological methods [Category] COVID19(2023년), SARS, 치료기술, [키워드] addition affecting automated COVID-19 COVID-19 diagnosis COVID-19 test cycle extraction FIVE genetic material gold gold standard high correlation house magnetic bead Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples nasopharyngeal swabs nucleic acid nucleic acids pandemic platform positive protocol public health purification qPCR quantitative PCR Rapid reagents reduced Reverse transcription quantitative PCR RNA RNA extraction RNA extraction kits RT-qPCR SARS-CoV-2 SARS-CoV-2 detection the mean virus detection [DOI] 10.1016/j.jviromet.2021.114414 PMC 바로가기 [Article Type] Article
Antibody Responses to BNT162b2 Vaccination in Japan: Monitoring Vaccine Efficacy by Measuring IgG Antibodies against the Receptor-Binding Domain of SARS-CoV-2Research Article Published on 2022-01-192022-10-30 Journal: Microbiology Spectrum [Category] COVID-19, COVID19(2023년), SARS, [키워드] acute respiratory syndrome age analyzed antibody antibody isotype antibody production Antibody Response BNT162b2 BNT162b2 vaccine cause clinical setting Cohort coronavirus coronavirus disease correlated correlation COVID-19 detect determine dose Efficacy enzyme enzyme-linked immunosorbent Factors female Gender high correlation hypertension IgA IgG IgG level IgM immunoassay individual individuals information Japan Japanese Laboratory levels of antibodies males mass vaccination MONITOR monitoring mRNA vaccine negative correlation Neutralizing activity of BNT162b2 powerful tool predict provide RBD reported response SARS-CoV-2 SARS-CoV-2 vaccination second dose second vaccination sera Serological assay significantly significantly higher the receptor-binding domain vaccinated individual vaccination Vaccination strategy Vaccine was measured were measured [DOI] 10.1128/spectrum.01181-21 PMC 바로가기 [Article Type] Research Article
Analytical performances of the AMPLIQUICK ® Respiratory Triplex assay for simultaneous detection and differentiation of SARS-CoV-2, influenza A/B and respiratory syncytial viruses in respiratory specimens호흡기 시편에서 SARS-COV-2, 인플루엔자 A/B 및 호흡기 융기 바이러스의 동시 검출 및 분화를위한 Ampliquick ® 호흡기 삼중 탈수 분석의 분석 성능Research Article Published on 2022-01-052022-09-10 Journal: PLoS ONE [Category] 진단, 치료기술, [키워드] 2019-nCoV assay acute respiratory syndrome acute respiratory syndrome coronavirus analyses assays Chain Reaction comparable Concordance coronavirus cycle threshold Diagnosis diagnostics differentiation evaluated France high correlation Influenza influenza A influenza B Manifestations multiplex observation Panel Patient polymerase chain reaction positive positive sample qualitative detection respiratory Respiratory samples respiratory specimen respiratory specimens respiratory syncytial virus respiratory tract samples respiratory viral infection respiratory viral infections RSV SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specimen Therapeutic approach therapeutic approaches triplex Viral virus viruses [DOI] 10.1371/journal.pone.0262258 PMC 바로가기 [Article Type] Research Article
Two novel SARS-CoV-2 surrogate virus neutralization assays are suitable for assessing successful immunization with mRNA-12732개의 새로운 SARS-CoV-2 대리 바이러스 중화 분석은 mRNA-1273을 사용한 성공적인 면역 평가에 적합합니다.Article Published on 2022-01-012022-09-12 Journal: Journal of virological methods [Category] SARS, 진단, [키워드] anti-S IgG biosafety classical COVID-19 effort Genscript Health care worker high correlation humoral immunization inactivated individual Laboratory Laboratory test mRNA-1273 Neutralization assay Neutralizing activity neutralizing SARS-CoV-2 antibody Patient SARS-CoV-2 SARS-CoV-2 vaccines second vaccination sensitivity sera specificity Spike-based vaccine spike-based vaccines Successful vaccination surrogate surrogate virus neutralization assay sVNT Switzerland Test the RBD time-consuming USA vaccination Vaccine Virus neutralization virus neutralization assay whole virus vaccines [DOI] 10.1016/j.jviromet.2021.114297 PMC 바로가기 [Article Type] Article
Automated quantification of COVID-19 pneumonia severity in chest CT using histogram-based multi-level thresholding segmentationResearch Published on 2021-12-092022-10-31 Journal: The Egyptian Journal of Radiology and Nuclear Medicine [Category] COVID-19, [키워드] automated Chest CT Clinical severity Computed tomography computed tomography (CT) consolidation correlated correlation COVID-19 COVID-19 pneumonia patients Critical CT scan enrolled fatal disease Follow-up GGOs ground-glass opacity high correlation Histogram-based Intubated intubation lung Lung CT lung lesion Lungs Metrics Mild moderate Oxygenation Patient percentage performed Pneumonia quantification Quantification method Quantitative analysis quantitative assessment Quantitative imaging Radiologists Result Retrospective study risk stratification semi-quantitative severity severity scoring Spearman’s correlation Support the disease the patient two group volumetric was used [DOI] 10.1186/s43055-021-00602-1 PMC 바로가기 [Article Type] Research