Convalescent plasma – An insight into a novel treatment of covid-19 ICU patientsResearch article Published on 2022-07-012022-10-05 Journal: Transfusion and apheresis science : official journ [Category] COVID19(2023년), SARS, 치료법, [키워드] age antivirals association average Blood Blood Group Clinical outcome clinical outcomes clinically Comorbidities conducted convalescent plasma Cytokine storm disease Efficacy female gender females Gender guidelines ICU ICU patient ICU Patients include monoclonal antibody overall mortality Part Patient patient survival patients plasma positive remained Steroids survival the patient therapy Tocilizumab transfused treatment of COVID-19 [DOI] 10.1016/j.transci.2022.103497 [Article Type] Research article
Incidence and effects of deep vein thrombosis on the outcome of patients with coronavirus disease 2019 infectionObservational Study Published on 2022-07-012022-10-05 Journal: Journal of vascular surgery. Venous and lymphatic [Category] 임상, [키워드] 95% CI 95% confidence interval adjusted age Analysis anticoagulation ARDS Characteristics comparison contributing to coronavirus disease COVID-19 COVID-19 group COVID-19 patient COVID-19 patients Deep vein Deep vein thrombosis determine distress DVT Effect Factor ICU ICU Patients incidence increased mortality Infection intensive care Limited male Mortality multiple organ failure non-COVID-19 patient Observational cohort study occur outcome outcomes Patient patients with COVID-19 patients without COVID-19 performed Primary outcome Prophylactic receiving reported retrospective risk factor Standard Standard-dose surgical syndrome therapy Thromboprophylaxis thrombosis trauma trauma patient treated ventilatory support [DOI] 10.1016/j.jvsv.2021.10.013 PMC 바로가기 [Article Type] Observational Study
Long pentraxin 3 as a marker of COVID-19 severity: evidences and perspectivesCOVID-19 심각성 지표로서의 긴 펜트락신 3: 증거 및 전망Article Published on 2022-06-152022-09-11 Journal: Biochemia Medica [Category] MERS, 바이오마커, [키워드] Accuracy analysed Analysis AUC Biomarkers C-reactive protein Care cell types Comorbidities confirmed COVID-19 case coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 severity CRP cut-off demonstrated disease severity Endpoint enzyme-linked immunosorbent enzyme-linked immunosorbent assay Evidence ferritin Hospital admission ICU ICU patient ICU Patients immune cell types Inflammation inflammation site inflammation sites inflammatory conditions intensive care units investigated Laboratory Laboratory parameters Laboratory test Laboratory tests Lactate lactate dehydrogenase Long marker material multivariate logistic regression non-ICU non-ICU patient non-ICU patients outcome Patient Perspective predict Previous studies previous study Ptx3 receiver recruited released RT-PCR sensitivity serum sample serum samples severe COVID-19 shown specificity the disease transferred was measured [DOI] 10.11613/BM.2022.020901 PMC 바로가기 [Article Type] Article
SCD14-ST and New Generation Inflammatory Biomarkers in the Prediction of COVID-19 OutcomeCovid-19 결과의 예측에서 SCD14-ST 및 신세대 염증 바이오 마커Article Published on 2022-06-132022-08-31 Journal: Biomolecules [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] addition Biomarker Biomarkers canonical clinical feature Clinical features COVID-19 COVID-19 mortality COVID-19 positive patients CRP cytokine Cytokine storm Cytokines cytokines IL-6 died discharged disease Generation ICU ICU Patients IL-10 IL-6 immune immune biomarkers Infection inflammatory biomarkers Inflammatory marker inflammatory markers inflammatory parameters Laboratory Longitudinal evaluation longitudinal study New new infection outcome Patient plasma-EDTA predict prediction prediction of disease. prognostic SARS-CoV-2 SCD14-ST severity significantly higher suPAR the disease to define were measured [DOI] 10.3390/biom12060826 PMC 바로가기 [Article Type] Article
Elevated plasma level of the glycolysis byproduct methylglyoxal on admission is an independent biomarker of mortality in ICU COVID-19 patients입원 시 해당과정 부산물인 메틸글리옥살의 혈장 수준 상승은 ICU COVID-19 환자의 사망률에 대한 독립적인 바이오마커입니다Article Published on 2022-06-092022-09-11 Journal: Scientific Reports [Category] MERS, 바이오마커, 치료기술, 치료법, [키워드] Admission Biomarker Biomarkers byproduct Care correlated COVID-19 patient COVID-19 patients CRP death died elevated enzyme Evidence evidence of explained glutathione Glycolysis high risk ICU ICU patient ICU Patients identify IL-1β independent inflammation markers Logistic regression analysis management methylglyoxal monocyte Monocytes Mortality on admission Patient plasma Plasma levels predict provide regression analysis survived therapeutic These data TNF-α uninfected control Variability [DOI] 10.1038/s41598-022-12751-y PMC 바로가기 [Article Type] Article
Quality of life and persistent symptoms after hospitalization for COVID-19. A prospective observational study comparing ICU with non-ICU patientsObservational Study Published on 2022-06-012022-10-04 Journal: Revista española de anestesiología y reanimació [Category] COVID19(2023년), SARS, 임상, [키워드] Acute respiratorydistress (ARDS) Calidad de vidarelacionada con lasalud cohort study COVID-19 COVID-19 patient critically ill patients decrease defined described develop Dificultad respiratoriaaguda (SDRA) discharged Dyspnea English Estado funcional Functional status Health Health-relatedquality of life hospital Hospital admission Hospitalization ICU ICU admission ICU patient ICU Patients no difference non-ICU patient Pacientes críticos pacientes hospitalizado Patient patients died patients hospitalized Primary outcome proportion Prospective prospective observational study prospectivo Quality Quality of life questionnaire reduced reported required SARS-CoV-2 Spanish Symptom Symptoms worsening [DOI] 10.1016/j.redare.2022.06.002 PMC 바로가기 [Article Type] Observational Study
Investigation of the value of precipitins in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients with a positive marker for Aspergillus speciesAspergillus 종에 대한 양성 마커를 가진 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 환자에서 침전물의 값 조사Article Published on 2022-05-282022-09-11 Journal: Medical mycology [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료기술, 치료제, [키워드] A. fumigatus acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 acute respiratory syndrome coronavirus-2 Antigen antigens Aspergillus Aspergillus fumigatus assays Biomarker Biomarkers Bronchoalveolar lavage Characteristics Clinical data Co-infection collected colonization coronavirus Culture electrosyneresis ELISA galactomannan Hospitalized house hypersensitivity pneumonitis ICU ICU patient ICU Patients Infection intensive care intensive care unit investigation male management marker median microbial Patient patients performed positive precipitins Prevalence pulmonary aspergillosis purified qPCR reported respiratory respiratory sample Respiratory samples SARS CoV SARS CoV-2 SARS-CoV-2 SARS-CoV-2 patient SARS-CoV-2 patients screened serology assays Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus significantly higher similarities similarity somatic antigen study population suggested survival rate t-test tracheal Tracheal aspirates tracheal aspirates. [DOI] 10.1093/mmy/myac031 PMC 바로가기 [Article Type] Article
Study protocol to test the efficacy of self-administration of dexmedetomidine sedative therapy on anxiety, delirium, and ventilator days in critically ill mechanically ventilated patients: an open-label randomized clinical trial중환자 기계 환기 환자의 불안, 섬망 및 인공 호흡기 일에 대한 덱스메데토미딘 진정 요법의 자가 투여 효과를 테스트하기 위한 연구 프로토콜: 공개 라벨 무작위 임상 시험Article Published on 2022-05-162022-09-11 Journal: Trials [Category] 임상, [키워드] addition aggregate alertness alleviate alteration Anxiety approach approaches assigned Care change clinical Clinical practice clinical trial Consistency Course COVID-19 case COVID-19 pandemic Critically ill delirium Depression dexmedetomidine distress Efficacy eligible Eligible participants eligible patient Eligible patients enrolment equipment extubation finding flexible functional Functional status healthcare ICU ICU care ICU patient ICU Patients identify impacted imperative intensive care intensive care unit life management Mechanical mechanical ventilation mechanical ventilatory support mechanically ventilated mechanically ventilated patient mechanically ventilated patients medication Open-label opioid outcome Oxygenation Pain Patient patient symptom Patient symptoms physical Post-traumatic stress disorder Protective protocol Psychological well-being Quality of life randomization Randomized randomized clinical trial Randomly receiving recruitment Secondary objective Secondary objectives Sedation sedative Self-management Side effects significantly study population subset Symptom therapy Trial trial enrolment usual care ventilator ventilator-free day Ventilator-free days ventilatory support [DOI] 10.1186/s13063-022-06391-w PMC 바로가기 [Article Type] Article
Investigation of SARS-CoV-2 Epsilon Variant and Hospitalization Status by Genomic Surveillance in a Single Large Health System During the 2020-2021 Winter Surge in Southern California남부 캘리포니아의 2020-2021년 겨울 서지 동안 단일 대형 의료 시스템에서 게놈 감시에 의한 SARS-CoV-2 엡실론 변이체 및 입원 상태 조사Article Published on 2022-05-042022-09-11 Journal: American journal of clinical pathology [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission B.1.427 B.1.429 California collected coronavirus COVID-19 Epsilon Epsilon variant frequencies Frequency genomic Genomic surveillance health system Hospitalization hospitalized patients ICU ICU admission ICU patient ICU Patients intensive care intensive care unit investigation outpatients patients respiratory sample Respiratory samples SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe disease status Surveillance System unique variant virulent was performed Winter [DOI] 10.1093/ajcp/aqab203 PMC 바로가기 [Article Type] Article
Severe Acute Respiratory Syndrome Coronavirus 2 Viremia Is Associated With Coronavirus Disease 2019 Severity and Predicts Clinical Outcomes중증 급성 호흡기 증후군 코로나바이러스 2 바이러스혈증은 코로나바이러스 질병 2019 심각도와 연관되어 있으며 임상 결과를 예측합니다Observational Study Published on 2022-05-032022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] COVID19(2023년), MERS, SARS, 바이오마커, 임상, 진단, 치료기술, [키워드] 19 outcome 2 RNAemia 2 viremia acute respiratory syndrome acute respiratory syndrome coronavirus Admission Antibody titers bloodstream Care clinical clinical outcomes Cohort coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 CoV COVID COVID-19 COVID-19 patient COVID-19 severity cross-sectional discharge disease severity electron tomography hazard ratio Health Organization Hospitalized Host immune response host immune responses ICU ICU Patients immune responses immunostaining indicate Inflammatory biomarker Inpatients Level Mortality Neutralizing antibody titer neutralizing antibody titers non-ICU outcome outcomes Outpatient outpatients Patient pellet plasma plasma sample plasma samples quantified reflect respiratory SARS SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly significantly higher Viral Viral RNA Viremia virion virions virus particle virus particles Visualization vRNA WHO World Health Organization [DOI] 10.1093/cid/ciab686 PMC 바로가기 [Article Type] Observational Study