Pan-Indian Clinical Registry of Invasive Fungal Infections Among Patients in the Intensive Care Unit: Protocol for a Multicentric Prospective StudyProtocol Published on 2024-02-162024-09-05 Journal: JMIR Research Protocols [Category] update2024, [키워드] Antifungal antifungal resistance clinical registry descriptive method Diagnosis epidemiological epidemiological factor Fungal infection fungal infections ICU patient ICU Patients in-patient In-patients India Invasive fungal infections knowledge gaps long-term stay Mortality mycology Mycoses public health [DOI] 10.2196/54672 PMC 바로가기 [Article Type] Protocol
Angiotensin II induces reactive oxygen species, DNA damage, and T cell apoptosis in severe COVID-19Research article Published on 2022-09-012022-10-05 Journal: The Journal of Allergy and Clinical Immunology [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] ACE2 acute respiratory syndrome Admission age Angiotensin II angiotensin II receptor angiotensin-converting enzyme 2 antioxidant Apoptosis coronavirus coronavirus disease COVID-19 COVID-19 pathogenesis death DNA damage DNA oxidation ELISA flow cytometry form healthy controls high plasma level ICU ICU Patients immunofluorescence induce infected with SARS-CoV-2 Infection intensity intensive care Lymphocyte count Lymphocytes lymphopenia monocyte neighboring cells objective oxidative stress Patient patients patients with COVID-19 PBMC Predictive programmed cell death protease reactive oxygen species reactive oxygen specy receptor released responsible Result ROS ROS production SARS-CoV-2 severe COVID-19 survival T cell T-cell Trigger was measured were measured [DOI] 10.1016/j.jaci.2022.06.020 [Article Type] Research article
The predictive value of epicardial fat volume for clinical severity of COVID-19Research article Published on 2022-09-012022-10-05 Journal: Revista portuguesa de cardiologia [Category] 바이오마커, [키워드] adipose Admission age Analysis analyzed association C-reactive protein characteristic Clinical severity Computed tomography coronavirus disease COVID-19 CRP death disease severity Epicardial fat volume fat ferritin ferritin level hospitalized COVID-19 patients ICU ICU Patients IL-6 IL-6 level independent Inflammatory biomarker Inflammatory cytokine intensive care interleukin-6 male morbidity and mortality multivariate logistic regression objective occurred outcome Patient patients died patients with COVID-19 PCT positive correlation predict predicted Predictive primary composite endpoint procalcitonin Prognosis Result Retrospective study serum CRP severe complications significant level significantly higher tissue tomography Volume was determined were infected were measured with COVID-19 [DOI] 10.1016/j.repc.2021.05.016 [Article Type] Research article
Dynamic Alterations in the Respiratory Tract Microbiota of Patients with COVID-19 and its Association with Microbiota in the GutArticle Published on 2022-09-012022-11-15 Journal: Advanced Science [Category] 바이오마커, [키워드] Actinomyces alteration analyzed Bacteroide Biomarker Candida contributing to coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 progression determine Diagnosis disease Disease progression disease severity dynamic Enterococcus Fecal sample Gut gut microbiota ICU ICU Patients identify immune response Increases intensive care intensive care unit metagenome microbe microbial Microbiome microbiota mononuclear cell non-ICU pathway Patient patients patients with COVID-19 PBMC Peripheral blood positive correlation reduced respiratory respiratory microbiota. respiratory tract sequenced Significant significantly sputum Stage Streptococcus tract Treatment strategies with COVID-19 [DOI] 10.1002/advs.202200956 PMC 바로가기
Analysis of potential risk factors associated with COVID-19 and hospitalizationObservational Study Published on 2022-08-052022-10-05 Journal: Frontiers in Public Health [Category] SARS, 임상, [키워드] addition adjusted administration age Analysis analyzed association Care carried clearance Clinical characteristics comorbid patient Comorbidities Comorbidity Complication complications conducted Coronavirus disease 2019 COVID-19 COVID-19 pandemic cross-sectional database determine Factor Fever Gender group help hospital Hospitalization hypertension ICU admission ICU Patients indicated intensive care majority male medication medications non-ICU obesity Odds ratio outcome Patient patients hospitalized patients older Pneumonia potential risk predictor Prednisolone reduce Remdesivir retrieved retrospective risk factor Risk factors significantly statistically suggested Symptoms syndrome type 2 diabete understanding with COVID-19 [DOI] 10.3389/fpubh.2022.921953 PMC 바로가기 [Article Type] Observational Study
Thiol level and total oxidant/antioxidant status in patients with COVID-19 infectionCOVID-19 감염 환자의 티올 수치 및 총 산화제/항산화 상태Article Published on 2022-08-012022-09-11 Journal: Irish Journal of Medical Science [Category] 바이오마커, [키워드] antioxidant best blood cell C-reactive protein can be used Care contrary correlated COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients decrease determine disease Evidence ferritin ICU ICU admission ICU patient ICU Patients increase in Infection inflammatory markers intensive care intensive care unit level of care marker neutrophil non-ICU non-ICU patients not need oxidative stress Oxidative stress index parameter Pathogenesis Patient patients with COVID-19 positively correlated predictor procalcitonin recruited ROC Curve serum severity of COVID-19 Stress Support thiol two group two groups White blood cell worsening [DOI] 10.1007/s11845-021-02743-8 PMC 바로가기 [Article Type] Article
High levels of Von Willebrand factor markers in COVID-19: a systematic review and meta-analysisCOVID-19의 높은 수준의 Von Willebrand 요인 마커: 체계적인 검토 및 메타 분석Review Published on 2022-08-012022-09-11 Journal: Clinical and experimental medicine [Category] MERS, SARS, 바이오마커, [키워드] ADAMTS ADAMTS-13 Analysis COVID-19 COVID-19 patients death in COVID-19 elevated Factor factor VIII Factor VIII level Factors ICU patient ICU Patients increase in Level literature review marker Meta-analysis New Organ failure pathophysiology patients with COVID-19 performed Prognostic value SARS-CoV-2 virus severity of COVID-19 significantly higher spread to Stata status subgroup analysis subsequent systematic review therapeutic thrombosis VWF:AC VWF:Ag VWF:Co. was performed with COVID-19 [DOI] 10.1007/s10238-021-00769-x PMC 바로가기 [Article Type] Review
Aspergillus detection in airways of ICU COVID-19 patients: To treat or not to treat?ICU COVID-19 환자의 기도에서 아스페르길루스 검출: 치료할 것인가, 말 것인가?Case Reports Published on 2022-08-012022-09-11 Journal: Journal de mycologie médicale [Category] COVID19(2023년), SARS, 바이오마커, 치료기술, [키워드] absence airway Antifungal Antifungal treatment Antigen Aspergillus Aspergillus fumigatus Atypical COVID-19 Culture difficulty galactomannan highlight ICU ICU patient ICU Patients Intubated invasive Invasive pulmonary aspergillosis IPA management mechanically ventilated mechanically ventilated patient mechanically ventilated patients outcome Patient patients PCR Pneumonia pulmonary aspergillosis radiological Respiratory samples respiratory tract sample respiratory tract samples risk SARS CoV SARS CoV-2 SARS-CoV-2 SARS-CoV-2 pneumonia severe COVID-19 Symptomatology treat [DOI] 10.1016/j.mycmed.2022.101290 PMC 바로가기 [Article Type] Case Reports
Neurologic manifestations of COVID-19 in critically ill patients: results of the prospective multicenter registry PANDEMICObservational Study Published on 2022-07-162022-10-05 Journal: Critical Care [Category] COVID19(2023년), SARS, 임상, [키워드] 350 patients 95% CI age Analysis Care category cerebrospinal fluid Cohort Complication coronavirus disease COVID-19 COVID-19 patient COVID-19 patients Critical Critically ill diagnose disorder enrolled Evidence Factor functional hemorrhage hospital discharge ICU ICU Patients identify increasingly Infection intensive care intensive care unit male manifestation Manifestations morbidity Mortality multicenter nervous system neurologic neurologic disorder neurologic manifestations neurological manifestation New outcome Patient patients patients with COVID-19 performed positive Postinfectious predictor Prevalence reported reverse transcriptase PCR risk factor searched statistical analyses stroke study period surviving patient the mean treated were used [DOI] 10.1186/s13054-022-04080-3 PMC 바로가기 [Article Type] Observational Study
Intravenous IgM-enriched immunoglobulins in critical COVID-19: a multicentre propensity-weighted cohort study중요한 COVID-19에서 정맥내 IgM이 풍부한 면역글로불린: 다기관 성향 가중 코호트 연구Multicenter Study Published on 2022-07-072022-09-12 Journal: Critical Care [Category] COVID19(2023년), SARS, 진단, [키워드] 30-Day mortality acute respiratory distress addition applied Characteristics clinical clinically Cohort cohort study Complication concerning confidence interval controls coronavirus disease COVID-19 COVID-19 patients Cox regression models Critical Critically ill Critically ill patient daily dose dose early administration Effect Efficacy high mortality ICU ICU Patients Immunoglobulin immunoglobulin M immunoglobulins Inflammatory intravenous laboratory-confirmed Lung injury mechanical ventilation mechanically ventilated Mortality multicentre overcome Patient Primary outcome randomization randomized clinical trials retrospective SARS-CoV-2 selection bia statistical significance statistically statistically significant difference subgroup analysis subgroups survival treated Treatment treatment regimen two group was performed Weighting with COVID-19 [DOI] 10.1186/s13054-022-04059-0 PMC 바로가기 [Article Type] Multicenter Study