Advancing combination treatment with glycyrrhizin and boswellic acids for hospitalized patients with moderate COVID-19 infection: a randomized clinical trial중등도 COVID-19 감염으로 입원한 환자를 위한 글리시리진 및 보스웰산 병용 치료: 무작위 임상 시험Randomized Controlled Trial Published on 2022-03-012022-09-10 Journal: Inflammopharmacology [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] Advancing Adverse adverse events age Anti-inflammatory Antiviral assigned Boswellic aids clinical clinical status Clinical status score Combination combination treatment COVID-19 death diagnosed double-blind drugs Efficacy eligibility eligible Enrollment evaluated event Evidence FIVE glycyrrhizin hospital hospitalized patient hospitalized patients Identifier immunomodulating Infection institutional protocol IQR matching placebo median median age Mild mild to moderate moderate Moderate COVID-19 moderate infection moderate symptoms Mortality mortality rate outcome Patient PCR test Placebo placebo group placebo-controlled Primary outcome Randomized randomized clinical trial randomized trial Randomly receive receiving recent Recovery time Registered required Safe SARS-CoV-2 secondary secondary outcome significant decrease significant difference significantly shorter single-center small sample size study drug Symptoms the placebo group therapeutic Time to recovery Treatment treatment of COVID-19 Trial university variant variants [DOI] 10.1007/s10787-022-00939-7 PMC 바로가기 [Article Type] Randomized Controlled Trial
The Impact of COVID-19 Confinement on Cognition and Mental Health and Technology Use Among Socially Vulnerable Older People: Retrospective Cohort StudyRandomized Controlled Trial Published on 2022-02-222022-10-04 Journal: Journal of Medical Internet Research [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] All participant assessment association Baseline assessment boredom Care Cognition cognitive Cognitive impairment cohort study comparison conducted COVID-19 COVID-19 outbreak deleterious effect Dementia Depression Evidence Health Health services Health status Identifier Impact implementation information intervals Isolation leisure activities less lockdown Malaga measure mental health mental health problem Mild moderate multiple comparisons Nursing objective Older other variable outbreak outcome outcomes pandemic participant Perceived Perceived stress physical distancing populations Quality of life randomized clinical trials Registration report reported Research Result risk factor secondary outcome significantly social distancing social isolation Social support Spain Stress study population Support technology variables [DOI] 10.2196/30598 PMC 바로가기 [Article Type] Randomized Controlled Trial
Flavonoids for Treating Viral Acute Respiratory Tract Infections: A Systematic Review and Meta-Analysis of 30 Randomized Controlled Trials바이러스성 급성 호흡기 감염 치료를 위한 플라보노이드: 30건의 무작위 대조 시험에 대한 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-02-162022-09-11 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 임상, [키워드] achievement acute bronchitis acute respiratory tract infection adverse event adverse events Adverse reaction Adverse reactions alleviation alleviation of symptoms analyzed bronchial pneumonia bronchitis BSS changes in clearance common cold complementary and alternative medicine control group Controlled Controlled trial controlled trials COVID-19 duration of illness Efficacy analyses Efficacy analysis Efficacy and safety eligible flavonoid flavonoids Hospitalization ICU Identifier incidence infections Influenza intensity limitations mechanical ventilation meta-analyses meta-analysis Meta-analysis Mortality not differ oxygen Patient patients hospitalized performed positive RCT RCTs respiratory respiratory tract infection Respiratory tract infections Result review rhinosinusitis RT-PCR Safe Safety severity sinusitis subject substantial risk suggested Symptom Symptoms systematic review TNF-α tonsillitis tonsillopharyngitis tract treating trials TSS Tumor tumor necrosis tumor necrosis factor tumor necrosis factor-α upper respiratory tract upper respiratory tract infections Viral [DOI] 10.3389/fpubh.2022.814669 PMC 바로가기 [Article Type] Meta-Analysis
The Use of Wearable Pulse Oximeters in the Prompt Detection of Hypoxemia and During Movement: Diagnostic Accuracy Study저산소혈증의 즉각적인 감지 및 운동 중 착용형 맥박산소 측정기의 사용: 진단 정확도 연구Original Paper Published on 2022-02-152022-09-10 Journal: Journal of Medical Internet Research [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] Accuracy adjusted analyzed arterial blood arterial blood oxygen saturation blood oxygen Blood oxygen saturation calculate Care characteristic Clinical deterioration clinical setting comparable continuous monitoring COVID-19 disease detect detection Deterioration Diagnostic accuracy disease estimate evaluated hospital Hypoxemia hypoxia Identifier Isolation ISRCTN registry mHealth motion objective organization oximeter oxygen oxygen saturation Participants Patient patient monitoring patients with COVID-19 performance peripheral peripheral oxygen saturation Philip physiological pulse Pulse oximeter Pulse Oximeters receiver operating characteristic receiver operating characteristic curve receiving Registration reliability report required Result risk root rubbing sensitivity specificity Support Tablet Tapping was used Wavelet wearable pulse oximeter wearable technology [DOI] 10.2196/28890 PMC 바로가기 [Article Type] Original Paper
Risk Factors for COVID-19 in College Students Identified by Physical, Mental, and Social Health Reported During the Fall 2020 Semester: Observational Study Using the Roadmap App and Fitbit Wearable SensorsOriginal Paper Published on 2022-02-102022-10-31 Journal: JMIR Mental Health [Category] COVID-19, [키워드] addition alcohol analyses analysis Anxiety assessment association average Baseline assessment college College student comparison Complete Continuous COVID-19 COVID-19 diagnosis COVID-19 pandemic COVID-19 testing crisis criteria demographics described Diagnosis disorder Effect enrolled exacerbated Factor Factors Fitbit Formal Health highlight Identified Identifier identify index less measure Mental mental health mHealth Mobile health moderate multivariate model objective Observational outcome pandemic participant physical physical activity Physical health Prevalence problem public health measure recorded Registration report reported Result risk risk factor risk of COVID-19 self-report sensor state statistically significant student subsequent Substance use The United States the vaccine time triggered univariable variable was determined was obtained wearable wearable devices Well-being wellbeing with COVID-19 [DOI] 10.2196/34645 PMC 바로가기 [Article Type] Original Paper
Intensive Care Unit–Specific Virtual Reality for Critically Ill Patients With COVID-19: Multicenter Randomized Controlled TrialRandomized Controlled Trial Published on 2022-01-312022-10-04 Journal: Journal of Medical Internet Research [Category] SARS, 임상, [키워드] added control group Controlled controls COVID-19 Critical demonstrated Effect effective intervention facilitate feasible Follow-up Future groups hospital discharge ICU ICU treatment Identifier Ill IMPROVE intensive care Intervention intervention group males median age mental health multicenter Netherland no difference objective Patient patients post-intensive care syndrome Prevalence Prevent Psychological Psychological distress Quality of life Questionnaires Randomized Randomized controlled trial REALITY Registration report Research Result SARS-CoV-2 Satisfaction scored severity survivor Survivors treat Treatment virtual reality widespread [DOI] 10.2196/32368 PMC 바로가기 [Article Type] Randomized Controlled Trial
Challenges of Telemonitoring Programs for Complex Chronic Conditions: Randomized Controlled Trial With an Embedded Qualitative StudyRandomized Controlled Trial Published on 2022-01-262022-10-04 Journal: Journal of Medical Internet Research [Category] SARS, 임상, [키워드] Algorithm Analysis analyzed Anxiety Canada Care challenge chronic chronic conditions chronic disease clinical decision Clinical management collected complex component conceive condition conditions Controlled COVID-19 pandemic Depression diabetes Diabetes Mellitus Diagnosis directive evaluate Evidence expressed fluctuation form groups Guidance hcp Health Health Service Health status heart failure hypertension Identifier implementation improvement Interaction Intervention intervention group less management measure mobile phone multiple chronic conditions objective opinion outcome participant Patient physical positive Pragmatic Prevalence Primary outcome Program Qualitative Quality of life questionnaire Randomized Randomized controlled trial recruit recruited Registration report reported required Research Result secondary Secondary outcomes self-care Self-efficacy Self-management Standard of care statistical significance Support survey Telemedicine Telemonitoring tertiary health care Toronto uncontrolled hypertension [DOI] 10.2196/31754 PMC 바로가기 [Article Type] Randomized Controlled Trial
Immune-Mediated Mechanisms in Patients Testing Positive for SARS-CoV-2: Protocol for a Multianalysis StudyProtocol Published on 2022-01-252022-10-29 Journal: JMIR Research Protocols [Category] COVID-19, [키워드] Activation acute respiratory distress Analysis anamnestic Antigen antigens approved biochemical Blood blood monocyte CD4+ CD8+ T cell CD8+ T cells clinical analysis Clinical data collected Comorbidities Complete COVID-19 Cytokines detect develop Enrollment epidemiological Epidemiology ethics committee experimental analysis factor serum Factors function generate Genetic genetics healthy healthy subject help high mortality rate hyperactivity Hypothesis Identifier identify immune Immune cell immune response immune system Immunity immunological immunological profile immunology immunomodulation immunomodulatory implementation independent Infection Infectious disease initial innate immune response Laboratory lymphocyte mechanism monocyte Monocytes mononuclear cells natural killer cell Natural killer cells Novel coronavirus objective Patient patients patients older Peripheral blood Pfizer phenotype Population proof protection Protective protocol recognize Registration report Result risk SARS-CoV-2 Severe acute respiratory syndrome severe COVID-19 severe SARS-CoV-2 stimulate syndrome Testing therapeutic vaccination Vaccine viral infection virus White blood cell younger people [DOI] 10.2196/29892 PMC 바로가기 [Article Type] Protocol
A Model Predicting Mortality of Hospitalized Covid-19 Patients Four Days After Admission: Development, Internal and Temporal-External Validation입원 4일 후 입원한 Covid-19 환자의 사망률을 예측하는 모델: 개발, 내부 및 시간-외부 검증Cellular and Infection Microbiology Published on 2022-01-242022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 변종, [키워드] Admission age Alpha Alpha variant AUROC B.1.1.7 blood parameter C-reactive protein calibration slope Care characteristic clinical coronavirus COVID-19 creatinine cross Day develop development discharge explained Fever Final FIVE haematological parameter haematological parameters Health Health care Health care system Hospitalized hospitalized COVID-19 patients hospitalized patients hospitals Identifier in-hospital mortality internal Lactate lactate dehydrogenase linear mixed model Logistic regression Model Mortality mutations non-survivor Non-survivors objective Occurrence on admission parameter Patient Platelet Platelet count Prediction model prevalent prognostic model receiver operating characteristic receiver operating characteristic curve reduce Registration Result slope Support supported survival survivor validation variable variable selection variables Variation was done [DOI] 10.3389/fcimb.2021.795026 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Dissemination and Implementation of a Google Apple Exposure Notification System for COVID-19 Risk Mitigation at a National Public University: Protocol for a Pilot Evaluation Study in a Real-World SettingProtocol Published on 2022-01-192022-10-29 Journal: JMIR Research Protocols [Category] COVID-19, [키워드] acceptability acceptance addition adoption agency Apple approach belief cause Clemson University communication Contact tracing COVID-19 COVID-19 mitigation COVID-19 testing COVID-19 transmission Data collection determine develop dissemination element evaluate expected exposure exposure notification system facilitator for inclusion Google group help Identifier identify implementation Implementation science include Isolation Local maintenance mitigate Mitigation mobile phone technology Model National notification objective outbreak outcome pandemic protocol Public public health quarantine recommendation reduce report Result risk SARS-CoV-2 setting South Spread Strategy Support System technology the United State Transmission university university setting Usage virus was used [DOI] 10.2196/32567 PMC 바로가기 [Article Type] Protocol