An intersectional approach to identifying factors associated with anxiety and depression following the COVID-19 pandemic Research Published on 2022-07-012022-10-05 Journal: Scientific Reports [Category] 진단, [키워드] age Anxiety approach Care children COVID-19 pandemic cross-sectional Depression depressive symptom examined Factor Gender Generalized greater increasing age individuals Interaction mental health mental health burden pandemic Participants PHQ-9 Population practitioners psychiatrists representing respond Symptom variable women [DOI] 10.1038/s41598-022-15695-5 [Article Type] Research
Antibody responses and risk factors associated with impaired immunological outcomes following two doses of BNT162b2 COVID-19 vaccination in patients with chronic pulmonary diseases만성 폐질환 환자에서 BNT162b2 COVID-19 백신 2회 접종 후 손상된 면역학적 결과와 관련된 항체 반응 및 위험 인자Article Published on 2022-07-012022-09-12 Journal: BMJ Open Respiratory Research [Category] MERS, 진단, [키워드] 1:1 1.26 95% CI adjusted antibody concentration Antibody Response aRR association Asthma bronchiectasis Charlson Comorbidity Index chronic pulmonary disease cohort study Comorbidity Control controls copd epidemiology COVID-19 COVID-19 vaccination COVID-19 vaccine defined dose Factor fibrosis first vaccination functional geometric healthcare personnel Humoral response identify immunological immunological responses Immunosuppression immunosuppressive Inclusion increasing age Interaction interstitial Interstitial Fibrosis lowest mRNA neutralising neutralising antibody of BNT162b2 outcome Patient Poisson regression Prednisolone Primary outcome Prospective quartile Receptor binding domain reported Responder response responses risk risk factor secondary outcome tested vaccination [DOI] 10.1136/bmjresp-2022-001268 PMC 바로가기 [Article Type] Article
Safety evaluation of the single-dose Ad26.COV2.S vaccine among healthcare workers in the Sisonke study in South Africa: A phase 3b implementation trial남아프리카의 Sisonke 연구에서 의료 종사자를 대상으로 한 단회 용량 Ad26.COV2.S 백신의 안전성 평가: 3b상 시행 시험Clinical Trial Published on 2022-06-212022-09-12 Journal: PLoS Medicine [Category] MERS, 임상, 진단, [키워드] 48 hour Ad26.COV2.S vaccine adverse event AEs African age body ache breakthrough infections categories clinical clinical trials collected COVID-19 COVID-19 infection death demonstrated Effectiveness eligible evaluated expected Fever Final first vaccination Frequency HCW HCWs headache healthcare healthcare worker hospitalisations Immune system disorder implementation Implementation study IMPROVE incidence rate increasing age Infection injection site pain janssen men morbidity MOST National nervous system disorder occurred Open-label Pan participant Participants Phase 3 trials reactogenicity reactogenicity event Registered registry reported SAE SAEs safety evaluation safety profile serious AE single-arm design South South Africa Support Symptoms syndrome System thrombosis Trial triggered vaccination Vaccine [DOI] 10.1371/journal.pmed.1004024 PMC 바로가기 [Article Type] Clinical Trial
Clinical characteristics and risk factors for COVID-19 infection and disease severity: A nationwide observational study in EstoniaObservational Study Published on 2022-06-162022-10-04 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI 95%CI ACE2 expression ACE2 receptor affecting age and gender analysed association Cancer Cerebrovascular disease Characteristics clinical cohort study comorbid condition conditions contribute contributed Control Course COVID-19 COVID-19 diagnosis COVID-19 infection COVID-19 pandemic Critical Critical disease database died disease disease course Diseases Estonia expressed Factor Gender Government Health health system hospitalisation identify increased the risk increasing age Infection infection risk intensive care knowledge Liver disease Male sex modulating Myocardial infarction obesity outcome pathogenesis of SARS-CoV-2 positive predict Randomly renal renin-angiotensin system Research risk risk factor risk of infection risk stratification SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA selected severe COVID-19 severe COVID-19 disease severe disease severe disease course severity of COVID-19 Sex significantly Sociodemographic Study participants Taking tested Therapies tissues women [DOI] 10.1371/journal.pone.0270192 PMC 바로가기 [Article Type] Observational Study
Characteristics of postintubation dysphagia in ICU patients in the context of the COVID-19 outbreak: A report of 920 cases from a Brazilian reference centerObservational Study Published on 2022-06-162022-10-04 Journal: PLoS ONE [Category] 임상, [키워드] Admission affected assigned blocker body mass index Clinical data collected conducted COVID-19 Critical critical COVID-19 patients critical patient demographic disease dysfunction Dysphagia FOIS hospital hospital discharge ICU ICU admission ICU patient identify In-hospital In-hospital death increasing age indicated initial intake intensive care intubation multivariate logistic regression neurologic oral outcome Patient patients patients with COVID-19 presenting prospective observational cohort required Research resolved Result risk factor scale severity swallowing two group was collected with COVID-19 [DOI] 10.1371/journal.pone.0270107 PMC 바로가기 [Article Type] Observational Study
Immune and epithelial determinants of age-related risk and alveolar injury in fatal COVID-19치명적인 COVID-19에서 연령 관련 위험 및 폐포 손상의 면역 및 상피 결정인자Article Published on 2022-06-082022-09-12 Journal: JCI Insight [Category] MERS, 진단, [키워드] acute lung injury age aging alveolar alveolar injury Autopsy CD4+ CD8+ T cell Cell characterized contribute correlated COVID-19 cytotoxicity deficiency determinant Donor donors dysfunction early stage epithelial expressed fatal COVID-19 Gas exchange histopathological Immune cell increasing age individuals Infection lung lung damage Lung injury lymphocyte Macrophage Macrophage infiltration macrophages Older organ pathological stage performed pulmonary Pulmonary surfactants respiratory risk susceptibility T cell activation T cells underlie uninfected widespread [DOI] 10.1172/jci.insight.157608 PMC 바로가기 [Article Type] Article
Digital medical history implementation to triage orthopaedic patients during COVID-19: Findings from a rapid cycle, semi-randomised A/B testing quality improvement projectCOVID-19 동안 심각한 정형 외과 환자에게 디지털 병력 구현 : 빠른주기, 반 랜가이션 A/B 테스트 품질 개선 프로젝트에서 결과Randomized Controlled Trial Published on 2022-06-012022-08-31 Journal: Musculoskeletal care [Category] MERS, 임상, 치료제, [키워드] A/B testing age analysed approach Care clinic clinic visit collected completion rate conducted COVID-19 COVID-19 pandemic crisis Descriptive statistics determine Digital digital medical history finding FIVE Health Health care health care transformation health information helping highest impacted implementation improvement increasing age Injury Intensive Intervention Logistic regression medical history multivariable logistic regression Musculoskeletal musculoskeletal care notable Odds ratio Patient patient groups patients Quality Quality improvement randomised resource the patient unique utilised value-based health care. was used were used [DOI] 10.1002/msc.1605 PMC 바로가기 [Article Type] Randomized Controlled Trial
First-generation BNT162b2 and AZD1222 vaccines protect from COVID-19 pneumonia during the Omicron variant emergence1세대 BNT162b2 및 AZD1222 백신은 오미크론 변이체가 출현하는 동안 COVID-19 폐렴으로부터 보호합니다Article Published on 2022-06-012022-09-11 Journal: Public health [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval administration analyses analyzed Arterial hypertension AZD1222 B.1.1.529 BNT162 vaccine BNT162b2 ChAdOx1 ChAdOx1 nCoV-19 CIs Comorbidity conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pneumonia diabetes Diabetes Mellitus disease elapsed evaluated Factor Gender greater higher risk hypertension identify illness onset Immunosuppression increased risk increasing age individual individuals Kidney disease linear models Manifestations nCoV Obstructive omicron Omicron variant Pneumonia pneumonia case pneumonia cases PROTECT protective effect reduce retrospective cohort study risk risk of COVID-19 risk ratio risk ratios RRs SARS-CoV-2 variants smoking subject type 2 diabete Type 2 diabetes mellitus Vaccine variant [DOI] 10.1016/j.puhe.2022.04.001 PMC 바로가기 [Article Type] Article
Factors associated with anti-SARS-CoV-2 antibody titres 3 months post-vaccination with the second dose of BNT162b2 vaccine: a longitudinal observational cohort study in western GreeceBNT162b2 백신 2차 접종 후 3개월째 항-SARS-CoV-2 항체 역가와 관련된 요인: 서부 그리스의 종단 관찰 코호트 연구Observational Study Published on 2022-05-192022-09-12 Journal: BMJ Open [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] 95% CI age age and gender analyses anti-SARS-CoV-2 antibody Antibody Response Antibody titre antibody titres association baseline body mass index correlation COVID-19 COVID-19 pandemic COVID-19 vaccination criteria diabete diabetes Diseases eligible evaluate Factor Gender general endocrinology Greece healthcare highlighting Humoral immunity hypertension identify increasing age individuals Infectious diseases information Interaction investigated linear Linear regression analysis lower quartile male men Multiple obese Observational cohort study of BNT162b2 parameter Patra Patras positive receiving response to vaccination SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody titre SARS-CoV-2 antibody titres SARS-COV-2 infection second dose smoking state statistically significant subject tested titre Tobacco university vaccination Vaccine vitamin D level vitamin D levels was performed was used were excluded women [DOI] 10.1136/bmjopen-2021-057084 PMC 바로가기 [Article Type] Observational Study
Electroencephalography at the height of a pandemic: EEG findings in patients with COVID-19Research article Published on 2022-05-012022-10-05 Journal: Clinical neurophysiology : official journal of the [Category] 바이오마커, 유전자 메커니즘, [키워드] abnormality Cohort collected Comorbidities COVID-19 COVID-19 pandemic COVID-19 patient Critical died discharge EEG electroencephalogram Electroencephalography epileptiform Factor Hemorrhagic Stroke hospital hospitalized COVID-19 patient hospitalized COVID-19 patients increasing age indication Injury MOST NeuroCOVID New York City nonspecific objective occurred outcome Patient patients patients with COVID-19 performed Result retrospective Risk factors Seizure Seizures severe COVID-19 Significance stroke Treatment [DOI] 10.1016/j.clinph.2022.03.001 [Article Type] Research article