Prior aerosol infection with lineage A SARS-CoV-2 variant protects hamsters from disease, but not reinfection with B.1.351 SARS-CoV-2 variant혈통 A SARS-CoV-2 변이체를 사용한 이전 에어로졸 감염은 햄스터를 질병으로부터 보호하지만 B.1.351 SARS-CoV-2 변이체에 의한 재감염은 보호하지 않습니다.Research Article Published on 2021-06-262022-09-10 Journal: Emerging Microbes & Infections [Category] SARS, 변종, 진단, [키워드] aerosol aerosol exposure anamnestic response B.1.351 caused circulation Contact direct contact disease exposure to fomite hamster hamsters HCoV HCoV-19 Heterologous humoral induce Infection Infection route infection with SARS-CoV-2 Infectious virus initial intranasal Lineage lose weight low dose Lungs majority mild infection naïve neutralization neutralize Neutralizing onward transmission pathology Prevent PROTECT protective immunity provide Pulmonary pathology Reinfection remained Replication SARS-CoV-2 SARS-CoV-2 variant seroconverted Syrian hamster These data titre titres Transmission triggered variants variants of concern virus VoC VOCs WA1 weight weight loss [DOI] 10.1080/22221751.2021.1943539 PMC 바로가기 [Article Type] Research Article
Aerosol transmission, an indispensable route of COVID-19 spread: case study of a department-store clusterResearch Article Published on 2020-12-252022-10-31 Journal: Frontiers of Environmental Science & Engineering [Category] COVID-19, [키워드] activities aerosol transmission analyzed Characteristics China Cluster COVID-19 Department dependent on environmental condition environmental factor Epidemiologic characteristic epidemiological Factor Figuring Hospitalization Incubation indicated Infection route Isolation median occur outbreak outbreak sites Patient released respiratory tract RNA SARS-CoV-2 Spread SRAS-CoV-2 temperature the SARS-CoV-2 Transmission unique Ventilation widespread with COVID-19 [DOI] 10.1007/s11783-021-1386-6 PMC 바로가기 [Article Type] Research Article
A Genome Epidemiological Study of SARS-CoV-2 Introduction into JapanResearch Article Published on 2020-11-112022-10-30 Journal: mSphere [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Asia association China Cluster Clusters collected contribute coronavirus coronavirus disease COVID-19 COVID-19 case demonstrated epidemiological Epidemiology Europe evaluate Genome genome sequence Government Haplotype haplotypes help highlight Immigration Infection Infection route isolate Japan Japanese knowledge Measures mitigate network analysis outbreak patients PCR test performed RNA sample SARS-CoV-2 specimen Spread suggested Support Surveillance Travel was performed whole-genome sequencing [DOI] 10.1128/mSphere.00786-20 PMC 바로가기 [Article Type] Research Article
Machine learning prediction for mortality of patients diagnosed with COVID-19: a nationwide Korean cohort studyArticle Published on 2020-10-302022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, [키워드] age Asthma Cluster Cohort cohort study Comorbidity Contact COVID-19 patients Cox proportional hazard demonstrated develop Diabetes Mellitus diagnosed died Follow-up hypertension increased risk Infection Infection route information Isolation Korean Laboratory linear Lung disease machine machine learning Male sex medical resource Medical resources moderate Mortality operator pandemic Patient predict predictor Prognosis radiologic random receiver operating characteristics regression analysis sensitivity significantly Sociodemographic South Korea specificity spread of COVID-19 Support SVM Symptoms tested treated viral infection [DOI] 10.1038/s41598-020-75767-2 PMC 바로가기 [Article Type] Article
Psychological Status and Influencing Factors of Hospital Medical Staff During the COVID-19 OutbreakPsychology Published on 2020-08-042022-10-31 Journal: Frontiers in Psychology [Category] COVID-19, [키워드] 12-item General Health Questionnaire (GHQ-12) affecting analyzed coronavirus disease COVID-19 COVID-19 outbreak COVID-19 symptoms distress Factor GHQ-12 HCW HCWs Health care worker health care workers implementation infection control Infection route Influencing factors influenza pandemic information less measure medical staff outbreak participant positive preventive measure Prognosis Psychological Psychological distress psychological status psychological support questionnaire ranged reported Result risk factor scored SPSS status Treatment Wuhan [DOI] 10.3389/fpsyg.2020.01841 PMC 바로가기 [Article Type] Psychology
COVID-19: Presumed Infection Routes and Psychological Impact on Staff in Administrative and Logistics Departments in a Designated Hospital in Wuhan, ChinaPsychology Published on 2020-06-122022-10-31 Journal: Frontiers in Psychology [Category] COVID-19, [키워드] administrative and logistics departments analyzed baseline caused change China collected COVID-19 COVID-19 outbreak Department diagnosed Diagnosis disease emotional equipment Health help hospital Impact Infection Infection route Intervention logistics measure MOST Neutral nine no significant difference Nosocomial infection Nurse Protective Psychological Psychological distress psychological Impact Psychological intervention random route SARS-CoV-2 staff Stress the epidemic three group three groups uninfected university were infected with COVID-19 Wuhan Wuhan, China [DOI] 10.3389/fpsyg.2020.01501 PMC 바로가기 [Article Type] Psychology
The COVID-19 Pandemic in JapanReview Article Published on 2020-05-272022-10-29 Journal: Surgery today [Category] COVID-19, MERS, [키워드] caused China Clinical finding country COVID-19 COVID-19 pandemic Critical death effective epidemiological data global effort globe Increases Infection infection control Infection route information initial Japan medical resource New nosocomial outbreak pandemic pathology reached recorded Region reported representing required respond SARS-CoV-2 SARS-COV-2 infection Spread Transmission Vaccine [DOI] 10.1007/s00595-020-02033-3 PMC 바로가기 [Article Type] Review Article
Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirusResearch Article Published on 2017-11-152022-11-01 Journal: Science Advances [Category] Coronavirus, MERS, [키워드] Acidic alternative route basolateral Caco-2 cell caused cells demonstrated effective epidemiological epithelial Evidence Fatality rate histological examination Human human DPP4 human gastrointestinal tract Infection Infection route Inflammation inhibitor inoculated intestinal epithelial cells intestinal organoid intestinal tract less lethal infection Live virus lung tissues MERS-CoV MERS-CoV infection mice Middle East Patient progression respiratory infection respiratory syndrome coronavirus robust shown small intestine small intestines specimen Stool susceptible These data transgenic mice viral replication virological study virus transmission [DOI] 10.1126/sciadv.aao4966 PMC 바로가기 [Article Type] Research Article
Antibody-dependent infection of human macrophages by severe acute respiratory syndrome coronavirusResearch Published on 2014-05-062022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] activated acute respiratory syndrome ADE Analysis Anti-viral antibodies antibody Antibody-dependent enhancement binding Cell cells chimeric competent consequence coronavirus cytoplasmic dependent on downstream elicited ENhance evaluate Fcγ receptor FcγR Fluorescence full-length Health heat-inactivated human coronavirus human macrophage human macrophages human monocyte-derived macrophage IgGs immune Immune cell immune complex Infection Infection route information Lentiviral particle Macrophage Microscopy molecular mechanism naïve observation Occurrence Pathogens performed polymerase chain Pseudotypes Public Quantitative receptor receptors Replication reported response Result risk RT-PCR SARS-CoV SARS-CoV vaccine serum shown Signaling signaling domain signaling pathway spike Support susceptibility transcriptase Trimers vaccination virus [DOI] 10.1186/1743-422X-11-82 PMC 바로가기 [Article Type] Research