Development of an inhibiting antibody against equine interleukin 5 to treat insect bite hypersensitivity of horsesarticle Published on 2023-03-102024-09-05 Journal: Burma Med J [Category] update2024, [키워드] Antibody therapy Applied immunology biologics Biotechnology Inflammatory diseases [DOI] 10.1038/s41598-023-31173-y PMC 바로가기 [Article Type] article
Pathogenic role of cytokines in COVID-19, its association with contributing co-morbidities and possible therapeutic regimensReview Published on 2022-10-012023-07-10 Journal: Inflammopharmacology [Category] COVID19(2023년), [키워드] COVID-19 Cytokines release storm Inflammatory diseases Therapeutic interventions. [DOI] 10.1007/s10787-022-01040-9 PMC 바로가기 [Article Type] Review
Anti-glutathione S-transferase omega 1-1 (GSTO1-1) antibodies are increased during acute and chronic inflammation in humansArticle Published on 2022-09-292022-11-15 Journal: Clinical and experimental immunology [Category] SARS, 바이오마커, 치료기술, [키워드] antibody Auto-antibodies Autoimmune Biomarker cancer progression Cell chronic inflammation COVID-19 Critical cytosolic enzyme glutathione glutathione S-transferase omega-1 Human Inflammation Inflammatory diseases inflammatory pathway involved marker modulation Patient Potential biomarker rheumatoid arthritis SARS-CoV-2 serum the disease tissue trichinellosis variety [DOI] 10.1093/cei/uxac060 PMC 바로가기
A new-type HOCl-activatable fluorescent probe and its applications in water environment and biosystems새로운 유형의 HOCl 활성화 가능한 형광 프로브 및 물 환경 및 생물 시스템에서의 응용Article Published on 2022-09-152022-09-11 Journal: The Science of the total environment [Category] 치료기술, 치료제, [키워드] Accuracy Affect aggregate assistance Biotin biotinylated Cancer cancer cell Cancer cells cancer diagnosis Cell cells chlorine Concentration Consumption contribute convenience Corona COVID-19 Early Cancer expected Fluorescence fluorescent Fluorescent probe Health HOCl human body hypochlorite hypochlorous acid inflammatory disease Inflammatory diseases introduced kill membrane outbreak overexpressed oxygen PBS Precision probe reactive oxygen specy receptor ROS significant increase sodium sodium hypochlorite Spread Virus Disease viruses water Water samples. while [DOI] 10.1016/j.scitotenv.2022.156164 PMC 바로가기 [Article Type] Article
Immunomodulatory Mechanisms of Mesenchymal Stem Cells and Their Potential Clinical ApplicationsArticle Published on 2022-09-022022-11-16 Journal: International Journal of Molecular Sciences [Category] 유전자 메커니즘, [키워드] application Autoimmune disease Cell Characteristics chemokines clinical Clinical applications Contact contribute COVID-19 Cytokines disease Diseases Effect Engineering Factor Growth factors homing immune immune cells immune disorders Immune homeostasis immune response immunomodulation immunomodulatory immunomodulatory effect immunomodulatory property IMPROVE incurable Inflammatory diseases Inflammatory responses maintain mechanism mesenchymal stem cell mesenchymal stem cells (MSCs). MSC MSCs multifunctional Potential regenerative Regulation Secretome shown signaling molecules STEM stem cell systemic lupus erythematosus therapeutic strategy treat [DOI] 10.3390/ijms231710023 PMC 바로가기
The potential role of ischaemia-reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and therapeutic implicationsArticle Published on 2022-08-312022-11-15 Journal: Biochemical Journal [Category] 진단, [키워드] activities amyloid microclots antioxidants biochemical burst Capillaries cell activation conditions COVID disease element Evidence explain hyperinflammation hypoxia implication Inflammatory diseases initiated Injury involved ischaemia–reperfusion injury. Long Long COVID malaise marker mechanism mechanisms metabolite Occurrence oxidative stress pathology produced reactive oxygen specy relapsing reperfusion rheumatoid arthritis Safe therapeutic Therapeutic benefit variety [DOI] 10.1042/BCJ20220154 PMC 바로가기
Self-Reported Periodontal Disease and Its Association with SARS-CoV-2 Infection자가 보고된 치주 질환 및 SARS-CoV-2 감염과의 연관성Article Published on 2022-08-182022-09-11 Journal: International Journal of Environmental Research an [Category] SARS, 진단, 치료기술, [키워드] 1:1 ad hoc age blinded Case-control case-control studies case-control study conducted Control coronavirus COVID-19 COVID-19 pandemic COVID-19 symptom criteria cytokine death diagnostic disease epidemiological epidemiological studies Epidemiological study hyperinflammatory cytokine storm individual inflammatory disease Inflammatory diseases information manifestation median methodology New coronavirus number of symptom oral cavity oral manifestations p value participant periodontal periodontal disease positive question questionnaire recruited reported Result risk factor SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection SARS-CoV-2-positive individual SARS-CoV-2-positive individuals self-report severe complication severe complications Sex significantly Spread statistically statistically significant difference subject Symptom Symptoms the disease university with COVID-19 [DOI] 10.3390/ijerph191610306 PMC 바로가기 [Article Type] Article
Epipharyngeal Abrasive Therapy (EAT) Reduces the mRNA Expression of Major Proinflammatory Cytokine IL-6 in Chronic EpipharyngitisEpipharyngeal Abrasive Therapy(EAT)는 만성 인두염에서 주요 전염증성 사이토카인 IL-6의 mRNA 발현을 감소시킵니다Article Published on 2022-08-162022-09-11 Journal: International Journal of Molecular Sciences [Category] 유전자 메커니즘, [키워드] Abrasive addition aggregation Alpha analyzed anti-inflammatory effect Cell chronic chronic fatigue syndrome chronic inflammation contribute cough COVID cytokine cytokine network Cytokines Diseases effective epipharyngeal abrasive therapy (EAT) epipharyngitis epipharynx expression expression pattern fatigue fatigue syndrome Hypothesis IgA IgA nephropathy IL-6 IL-6 expression IMPROVE In situ hybridization induce Inflammatory cytokine Inflammatory cytokines Inflammatory diseases interleukin interleukin 6 interleukin 6 (IL-6) intractable involved Japan Local Long Long COVID Major mechanisms mRNA myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) nasal Nasal cavity Necrosis nephropathy Patient postnasal drip Proinflammatory cytokine reduced reported responsible Sedation significantly lower subject suggested suppressed suppression Symptom syndrome systemic inflammatory disease systemic inflammatory diseases systemic symptoms therapy TNFα treated Treatment Tumor tumor necrosis tumor necrosis factor tumor necrosis factor alpha tumor necrosis factor alpha (TNFα). upper respiratory tract [DOI] 10.3390/ijms23169205 PMC 바로가기 [Article Type] Article
Effects of non-steroidal anti-inflammatory drugs and other eicosanoid pathway modifiers on antiviral and allergic responses: EAACI task force on eicosanoids consensus report in times of COVID-19비스테로이드성 소염제 및 기타 에이코사노이드 경로 조절제가 항바이러스 및 알레르기 반응에 미치는 영향: COVID-19 시대의 에이코사노이드 합의 보고서에 대한 EAACI 태스크포스Article Published on 2022-08-012022-09-11 Journal: Allergy [Category] COVID19(2023년), SARS, 치료제, [키워드] allergic allergic diseases allergic inflammation allergy analgesic effect antagonist Anti-inflammatory anti-inflammatory drug Antipyretic Antiviral applied Asthma Biologicals biologicals. cannabinoids chronic inflammatory disease Consensus COVID-19 COVID-19 treatment Effect eicosanoid General population Horizon identify Inflammation Inflammatory diseases Interaction knowledge leukotriene leukotriene receptor antagonist leukotriene receptor antagonists LTRA mechanism mechanism of action medication medications NERD non-steroidal anti-inflammatory drug Non-steroidal anti-inflammatory drugs NSAID NSAIDS pandemic of COVID-19 pathway Pathways predict prostaglandin prostaglandin D2 Research Respiratory disease respiratory infections response SARS-CoV-2 selectivity Symptom therapy Treatment unmet need viral infection viral infections [DOI] 10.1111/all.15258 PMC 바로가기 [Article Type] Article
Platelets in the NETworks interweaving inflammation and thrombosis염증과 혈전을 뒤섞는 NETworks의 혈소판Review Published on 2022-08-012022-09-11 Journal: Frontiers in Immunology [Category] 치료기술, 치료제, [키워드] activate Bacterial Capillaries capillary characterized chemokine chemokines chromatin Clinical outcome Coagulation factors contribute contributing to Course COVID-19 COVID-19 pandemic COVID-19 patient Cytokine storm disease DNA engage ENhance Evidence expression Extracellular extracellular space Growth factors hemorrhage Hemostasis histone Histones host innate immunity immune response immunothrombosis IMPROVE increased mortality induce infiltration Inflammation Inflammatory diseases inflammatory signaling Interaction interface kill lesion lung majority mechanism microthrombi molecular mechanism NET NETs neutrophil neutrophil activation Neutrophil extracellular trap Neutrophil extracellular traps neutrophil infiltration Neutrophils other tissue other tissues pathogen Pathogens Pathways Patient Pattern recognition Pattern recognition receptors Platelet Platelets procoagulant Protein Proteins provide provided resulting signaling pathway subsequent surface expression survival target thrombi thrombosis thrombotic TLR2 TLR4 Topic TRAP Treatment vascular beds virus [DOI] 10.3389/fimmu.2022.953129 PMC 바로가기 [Article Type] Review