Assessment of oxidative stress markers in elderly patients with SARS-CoV-2 infection and potential prognostic implications in the medium and long termArticle Published on 2022-10-062022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 바이오마커, 진단, [키워드] Admission age Analysis anti-SARS-CoV-2 IgM assessment correlated correlation difference Elderly patient evaluate evaluated event group help higher risk Hospital admission hospital discharge identify immune response implication individual Inpatient marker median time medium morbidity Mortality Older oxidative stress parameter Patient plasma Plasma level predictor prognostic Protein quantified reactive reduced RT-qPCR SARS-COV-2 infection TBARS were assessed women [DOI] 10.1371/journal.pone.0268871 PMC 바로가기
Case growth analysis to inform local response to COVID-19 epidemic in a diverse U.S communityArticle Published on 2022-10-042022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료기술, [키워드] Analysis Community conducted COVID-19 COVID-19 epidemic COVID-19 pandemic Critical early stage effective growth healthcare hospital Hospitalized hospitals Houston Infection Inpatient Local local response molecular outbreak pandemic positive Rapid robust SARS-CoV-2 SARS-CoV-2 test Seven Spread Support Surveillance sustained tested [DOI] 10.1038/s41598-022-20502-2 PMC 바로가기
Increased symptom severity in adults and adolescents admitting to an inpatient psychiatric hospital during the COVID-19 pandemicResearch article Published on 2022-10-012022-10-05 Journal: Psychiatry research [Category] 진단, [키워드] Admission Adolescent Adult Anxiety children coronavirus disease-2019 COVID COVID-19 COVID-19 pandemic Depression disease dysregulation Effect effort emotional examined GAD-7 help hospital ideation identify Increased Inpatient less Level measure mental health mental illness nightmare Outbreaks pandemic PHQ-9 Psychiatric psychiatry reported significantly higher sleep quality Substance use symptom severity while [DOI] 10.1016/j.psychres.2022.114758 [Article Type] Research article
Using EHR data to identify coronavirus infections in hospitalized patients: Impact of case definitions on disease surveillanceArticle Published on 2022-10-012022-11-15 Journal: International journal of medical informatics [Category] COVID19(2023년), SARS, 치료제, [키워드] age and sex anti-IL6 Antiviral Case definition Characteristics Clinical diagnosis clinically cohort characteristics Complication coronavirus disease Coronavirus infection COVID COVID-19 diagnosed Disease surveillance EHR data Electronic health records. evaluate evaluated Health health system Hospitalized Hydroxychloroquine identify Impact Inpatient lab Laboratory laboratory confirmation Laboratory test laboratory-confirmed Myocardial infarction outcome outcomes overall mortality Patient patients hospitalized positive receive Record required SARS-CoV-2 The United States therapy with COVID-19 [DOI] 10.1016/j.ijmedinf.2022.104842 PMC 바로가기
Inpatient psychiatry response to the SARS-CoV-2 Omicron variant surgeArticle Published on 2022-10-012022-11-16 Journal: Psychiatry research [Category] COVID19(2023년), SARS, 변종, [키워드] Admission Admissions affected COVID-19 COVID-19 negative hospital hospitals implementation Infection infection control Inpatient occurred omicron Omicron variant Patient PCR PCR testing polymerase chain positive Psychiatric Psychiatric hospitals. psychiatry rapid increase required SARS-CoV-2 subsequent the SARS-CoV-2 the SARS-CoV-2 virus Transmissibility variant [DOI] 10.1016/j.psychres.2022.114746 PMC 바로가기
Real-life Evidence of Lower Lung Virulence in COVID-19 Inpatients Infected with SARS-CoV-2 Omicron Variant Compared to Wild-Type and Delta SARS-CoV-2 PneumoniaArticle Published on 2022-10-012022-11-16 Journal: Lung [Category] COVID19(2023년), SARS, 변종, [키워드] adult subject ambient animal model ARDS better respiratory function blood gas analysis Comorbidities consolidation COVID-19 Delta described evidence of explain hospital Hospitalization Immunity in vitro Infection Inpatient Italy less Lineage Lower lower mortality lower risk lung parenchyma observation omicron other variant Pneumonia preliminary finding replication capacity respiratory airway Respiratory failure SARS-CoV-2 severe respiratory failure Turin variants of concern virulence virulence. wild type [DOI] 10.1007/s00408-022-00566-7 PMC 바로가기
The Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19Article Published on 2022-10-012022-11-16 Journal: Annals of internal medicine [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI acute SARS-CoV-2 infection antibody Antigen baseline Biomarker body mass index Characteristics Clinical outcome clinically COVID-19 cross-sectional study delta variant discharge elevated ENhance enrolled Enrollment evaluate evaluated Factor Government greater higher odd hospital Hospital admission hospital discharge Hospitalized hospitalized patient hospitalized patients identify immunocompromising condition Infectious diseases Inpatient Laboratory less Level Logistic regression Male sex median Multiple multivariable N antigen nasal nasal swab Noninvasive ventilation Odds ratio operation outcome outcomes participant pathogenesis of COVID-19 pathogenesis of SARS-CoV-2 Patient patients with COVID-19 plasma Platform trial point-of-care polymerase chain predict quantification regression models Remdesivir renal impairment SARS-CoV-2 SARS-CoV-2 nucleocapsid severity speed Support Symptoms Therapeutics transcriptase viral replication was determined was measured were assessed worsened worsening [DOI] 10.7326/M22-0924 PMC 바로가기
Interpatient variability in the pharmacokinetics of remdesivir and its main metabolite GS-441524 in treated COVID-19 subjectsArticle Published on 2022-09-302022-11-15 Journal: Journal of Antimicrobial Chemotherapy [Category] SARS, 치료제, [키워드] affected age antiviral drug approved association baseline blood sample BMI calculated collected comparison Concentration COVID-19 COVID-19 patients COVID-19 severity Efficacy enrolled evaluated glomerular filtration rate GS-441524 ICU identify independent predictor Inpatient Inpatients inter-individual Liver function Logistic regression metabolite Multiple linear regression Multiple regression analysis parameter Patient pharmacokinetic plasma Remdesivir renal renal function required Research SARS-CoV-2 SARS-CoV-2 infections Sex Standard-dose statistical subject transaminase treated Treatment Variability variables were assessed were measured were used [DOI] 10.1093/jac/dkac234 PMC 바로가기
Kynurenine serves as useful biomarker in acute, Long- and Post-COVID-19 diagnosticsArticle Published on 2022-09-232022-11-15 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 치료기술, [키워드] Admission age Biomarker Blood Concentration concerning controls correlated COVID-19 COVID-19 monitoring CRP CRP value diagnosis and monitoring diagnostics disease Donor elevated group hospital Hospitalized hyperinflammation IL-6 immune system Inflammation inflammation diagnostics Inflammatory Inflammatory marker Inflammatory response innate immune response Innate immunity Inpatient interleukin-6 investigated involved Kynurenine kynurenine reference values. Long Long-COVID biomarkers long-lasting marker material P-value pathophysiology Patient patients with SARS-CoV-2 rehabilitation Saliva SARS-COV-2 infection sera serum significantly significantly higher subset Symptom syndrome the SARS-CoV-2 therapy were measured [DOI] 10.3389/fimmu.2022.1004545 PMC 바로가기
Complement and endothelial cell activation in COVID-19 patients compared to controls with suspected SARS-CoV-2 infection: A prospective cohort studyArticle Published on 2022-09-202022-11-15 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, [키워드] 30-Day mortality Activation Admission Analysis Bacterial Biomarker blood sample C5a cascade clinically suspected comparable complement complement system Concentration Control control group controls COVID-19 COVID-19 patient disease E-selectin elevated endothelial Endothelial cell endothelial cells Endothelium evaluate excluded females galectin-3 galectin-3. ICAM-1 ICU Inflammatory inflammatory condition Inpatient male non-infectious nonspecific occurred outcome Outpatient Patient Pneumonia presenting prospective cohort study recruited respiratory viral infections SARS-CoV-2 SARS-COV-2 infection SC5b-9 significantly significantly higher single-center study VCAM-1 [DOI] 10.3389/fimmu.2022.941742 PMC 바로가기