Increased respiratory dead space could associate with coagulation activation and poor outcomes in COVID-19 ARDSResearch article Published on 2022-10-012022-10-05 Journal: Journal of critical care [Category] 바이오마커, [키워드] Activation APACHE II ARDS Coagulation correlated COVID-19 COVID-19 patients Critically ill D-dimer D-dimer level determine discharge discharged enrolled help identify Increased Invasive mechanical ventilation less likelihood material measurement mechanical ventilation outcome outcomes P/F ratio Patient patients with COVID-19 performed Pneumonia primary endpoint Respiratory dead space Respiratory system Result static compliance subgroup of patient supported volumetric Volumetric capnography [DOI] 10.1016/j.jcrc.2022.154095 [Article Type] Research article
Effectiveness of prone position in acute respiratory distress syndrome and moderating factors of obesity class and treatment durations for COVID-19 patients: A meta-analysisResearch article Published on 2022-10-012022-10-05 Journal: Intensive & critical care nursing [Category] COVID19(2023년), SARS, 치료법, [키워드] 95% CI 95%CI acute respiratory distress acute respiratory distress syndrome Analysis article body mass index calculated CINAHL conducted coronavirus 2 COVID-19 COVID-19 patient effect size Effectiveness eligible experimental design Factor Final Invasive mechanical ventilation mean difference Meta-analysis methodology NCBI non-invasive ventilation obesity objective oxygen saturation PaO2 paO2/fiO2 Patient patients patients with COVID-19 prone Prone position prone positioning ProQuest Respiratory failure Result SARS-CoV-2 secondary outcome significantly SpO2 statistically significant syndrome Treatment Web of Science [DOI] 10.1016/j.iccn.2022.103257 [Article Type] Research article
Functional limitations 12 months after SARS-CoV-2 infection correlate with initial disease severity: An observational study of cardiopulmonary exercise capacity testing in COVID-19 convalescentsResearch article Published on 2022-10-012022-10-05 Journal: Respiratory medicine [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] Cardiopulmonary changes Clinical course Clinical severity convalescent correlated COVID-19 diffusion capacity disease Dyspnea Efficiency exercise Exercise capacity extracorporeal membrane oxygenation Factor Gas exchange impairment independent initial intensive care treatment Invasive mechanical ventilation limitation lung morbidity muscular offered outcome oxygen uptake parameter parenchymal participant Participants Patient PCR positive performed predicted prospective observational study provide Pulmonary function test Quality of life questionnaire reduced reported Result resulting risk factor SARS-COV-2 infection survivor Testing Treatment ventilatory Ventilatory capacity was reduced [DOI] 10.1016/j.rmed.2022.106968 [Article Type] Research article
Risk factors for disease severity and mortality of children with Covid-19: A study at a Vietnamese Children’s hospitalResearch article Published on 2022-10-012022-10-05 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료제, [키워드] age children children with COVID-19 close contact Comorbidities confirmed case COVID-19 COVID-19 case COVID-19 cases COVID-19 patients CRP died disease disease severity Dyspnea elevated Factor ferritin hospital independent Inflammatory marker Invasive mechanical ventilation male Mild moderate Mortality mortality rate neurologic Patient pediatric pediatrics positive positive RT-PCR Respiratory Support Result retrospective cohort study risk factor Risk factors RT-PCR SARS-CoV-2 severity treated Treatment underlying disease underlying diseases was performed [DOI] 10.1016/j.jiac.2022.06.010 [Article Type] Research article
Predictors of carbapenem-resistant Enterobacteriaceae (CRE) strains in patients with COVID-19 in the ICU ward: a retrospective case-control studyArticle Published on 2022-10-012022-11-16 Journal: The Journal of international medical research [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI 95% confidence interval acquisition acute respiratory syndrome Admission carbapenem carbapenem-resistant Enterobacteriaceae Care case-control study coronavirus corticosteroid treatment COVID-19 COVID-19 patient COVID-19 patients death determine enrolled Enterobacteriaceae hazard ratio ICU identify increased the risk independent risk factor Infection Invasive mechanical ventilation isolate Klebsiella Length majority Mortality mortality data Odds ratio Patient patients with COVID-19 patients without COVID-19 retrospective risk risk factor Risk factors Risk factors. significantly higher strain subdistribution Treatment two groups [DOI] 10.1177/03000605221129154 PMC 바로가기
Adding colchicine to tocilizumab in hospitalized patients with severe COVID-19 pneumonia: An open-label randomized controlled trialArticle Published on 2022-09-302022-11-15 Journal: Medicine [Category] SARS, 진단, [키워드] 1:1 added Adding Analysis antagonists Anti-inflammatory anti-inflammatory agent approved cascade center Colchicine Corporation cytokine Cytokine storm Efficacy and safety Ethics evaluate hospitalized patient IL-6 IL-6 blockade include Inflammasome inhibiting institutional review board Invasive mechanical ventilation Local mechanism of action Mortality NLRP3 Open-label Patient peer-reviewed Primary outcome Randomized Randomized controlled trial receptor receptor protein reduce Result risk safety profile severe COVID-19 Severe COVID-19 pneumonia Study protocol submitted Tocilizumab upstream [DOI] 10.1097/MD.0000000000030843 PMC 바로가기
Characteristics and outcomes of SARS-COV 2 critically ill patients after emergence of the variant of concern 20H/501Y.V2: A comparative cohort studyArticle Published on 2022-09-302022-11-16 Journal: Medicine [Category] SARS, 변종, [키워드] 24 hours 95 % CI 95% CI 95% confidence interval absence Admission Analysis change Characteristics cohort of patient cohort study Complete coronavirus 2 Critical care Critically ill patient demographic data dominant expected Fever forest higher risk ICU immunological improvement increased risk Indian Ocean indicated intensive care Invasive mechanical ventilation island less Lineage management Mayotte Mortality outcome outcomes Patient patients performed respiratory Respiratory failure SARS-CoV-2 second wave severe patients severity suggested survival Transmissibility unique VAP variant Ventilator-associated pneumonia Viral genome sequencing VoC [DOI] 10.1097/MD.0000000000030816 PMC 바로가기
TNFRSF1B and TNF Variants Are Associated With Differences in Levels of Soluble Tumor Necrosis Factor Receptors in Patients With Severe COVID-19Article Published on 2022-09-132022-11-16 Journal: The Journal of Infectious Diseases [Category] 변종, [키워드] association coronavirus disease COVID-19 COVID-19 severity determine difference ELISA evaluated exhibited expression Factor genetic study Genetic variant genetic variants genetics Genetics. Genotype genotypes implicated IMV Invasive mechanical ventilation Level no difference paO2/fiO2 Patient patients patients with COVID-19 plasma plasma sample receptor severe COVID-19 severity TNF TNF-α TNFR1 TNFR2 TNFRSF1A TNFRSF1B Tumor tumor necrosis factor-α variant was used were used with COVID-19 [DOI] 10.1093/infdis/jiac101 PMC 바로가기
Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trialArticle Published on 2022-09-072022-10-06 Journal: The Lancet. Respiratory Medicine [Category] COVID19(2023년), SARS, 진단, [키워드] 1:1 95% CI Acute kidney injury acute respiratory distress addition all-cause mortality all-cause mortality rate Analysis antibody assigned Belgium Block randomisation Brazil C5a Critically ill defined determine died dose double-blind eligible excluded France Germany hazard ratio hospital hospital discharge IMPROVE intravenously intubation invasive Invasive mechanical ventilation ITT analysis Kaplan-Meier analysis matching placebo mechanically ventilated patient monoclonal antibody Mortality multicentre Netherlands Older one patient outcome PaO participant Patient patient population phase 2 trial phase 3 trial Placebo placebo-controlled Pneumonia primary analysis Primary outcome random assignment randomised Randomly receive receiving reduced Registered reported Research Russia Safe safety analysis Safety analysis SARS-COV-2 infection Septic shock shown significant decrease significantly South Africa Standard of care survival TEAE the placebo group therapy Treatment treatment-emergent adverse event variant vilobelimab viral infections was performed with COVID-19 [DOI] 10.1016/S2213-2600(22)00297-1 PMC 바로가기 [Article Type] Article
U-shaped association between abnormal serum uric acid levels and COVID-19 severity: reports from the Japan COVID-19 Task ForceResearch article Published on 2022-09-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 바이오마커, 유전자 메커니즘, [키워드] addition Admission association body mass index Clinical characteristics co-morbidities Cohort COVID-19 COVID-19 severity enrolled force High serum uric acid Hyperuricemia Hypouricemia identify IMV increased risk Invasive mechanical ventilation Japan Japanese Laboratory Logistic regression analysis Low serum uric acid objective Odds ratio Older outcomes Patient Respiratory care Result serum severity significantly uric acid with COVID-19 [DOI] 10.1016/j.ijid.2022.07.014 [Article Type] Research article